Aliases for DOK6 Gene
External Ids for DOK6 Gene
Previous HGNC Symbols for DOK6 Gene
Previous GeneCards Identifiers for DOK6 Gene
DOK6 is a member of the DOK (see DOK1; MIM 602919) family of intracellular adaptors that play a role in the RET (MIM 164761) signaling cascade (Crowder et al., 2004 [PubMed 15286081]).[supplied by OMIM, Mar 2008]
GeneCards Summary for DOK6 Gene
DOK6 (Docking Protein 6) is a Protein Coding gene. Among its related pathways are GDNF-Family Ligands and Receptor Interactions and RET signaling. Gene Ontology (GO) annotations related to this gene include insulin receptor binding. An important paralog of this gene is DOK5.
UniProtKB/Swiss-Prot Summary for DOK6 Gene
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance.