Aliases for DOK6 Gene
External Ids for DOK6 Gene
Previous HGNC Symbols for DOK6 Gene
Previous GeneCards Identifiers for DOK6 Gene
DOK6 is a member of the DOK (see DOK1; MIM 602919) family of intracellular adaptors that play a role in the RET (MIM 164761) signaling cascade (Crowder et al., 2004 [PubMed 15286081]).[supplied by OMIM, Mar 2008]
GeneCards Summary for DOK6 Gene
DOK6 (Docking Protein 6) is a Protein Coding gene. Among its related pathways are RET signaling and Developmental Biology. Gene Ontology (GO) annotations related to this gene include insulin receptor binding. An important paralog of this gene is DOK5.
UniProtKB/Swiss-Prot Summary for DOK6 Gene
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance.