Aliases for DOK3 Gene
External Ids for DOK3 Gene
Previous GeneCards Identifiers for DOK3 Gene
GeneCards Summary for DOK3 Gene
DOK3 (Docking Protein 3) is a Protein Coding gene. Diseases associated with DOK3 include Myeloproliferative/Lymphoproliferative Neoplasms, Familial. Among its related pathways are B Cell Receptor Signaling Pathway (sino) and Innate Immune System. Gene Ontology (GO) annotations related to this gene include insulin receptor binding. An important paralog of this gene is DOK1.
UniProtKB/Swiss-Prot for DOK3 Gene
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity).