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The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] See more...
Aliases for DNPEP Gene
Aliases for DNPEP Gene
External Ids for DNPEP Gene
- HGNC: 2981
- Entrez Gene: 23549
- Ensembl: ENSG00000123992
- OMIM: 611367
- UniProtKB: Q9ULA0
Previous GeneCards Identifiers for DNPEP Gene
- GC02M218261
- GC02M218959
- GC02M220201
- GC02M220440
- GC02M220063
- GC02M219946
- GC02M220238
- GC02M212091
Summaries for DNPEP Gene
-
The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
GeneCards Summary for DNPEP Gene
DNPEP (Aspartyl Aminopeptidase) is a Protein Coding gene. Diseases associated with DNPEP include Nemaline Myopathy 9 and Tarsal-Carpal Coalition Syndrome. Gene Ontology (GO) annotations related to this gene include metallopeptidase activity and aminopeptidase activity.
UniProtKB/Swiss-Prot Summary for DNPEP Gene
-
Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important role in intracellular protein and peptide metabolism.
Additional gene information for DNPEP Gene
- HGNC(2981)
- Entrez Gene(23549)
- Ensembl(ENSG00000123992)
- OMIM(611367)
- UniProtKB(Q9ULA0)
- Open Targets Platform(ENSG00000123992)
- Search for DNPEP at DataMed
- Search for DNPEP at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DNPEP Gene
Genomics for DNPEP Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for DNPEP Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around DNPEP on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for DNPEP
- Top Transcription factor binding sites by QIAGEN in the DNPEP gene promoter:
-
- ATF-2
- c-Jun
- FOXO1
- FOXO1a
- MyoD
- TBP
Genomic Locations for DNPEP Gene
Genomic Locations for DNPEP Gene
- chr2:219,372,043-219,400,022
- (GRCh38/hg38)
- Size:
- 27,980 bases
- Orientation:
- Minus strand
- chr2:220,238,180-220,264,744
- (GRCh37/hg19)
- Size:
- 26,565 bases
- Orientation:
- Minus strand
Genomic View for DNPEP Gene
Genes around DNPEP on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q35 by HGNC
- 2q35 by Entrez Gene
- 2q35 by Ensembl
DNPEP Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DNPEP Gene
Proteins for DNPEP Gene
-
Protein details for DNPEP Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9ULA0-DNPEP_HUMAN
- Recommended name:
- Aspartyl aminopeptidase
- Protein Accession:
- Q9ULA0
- Q9BW44
- Q9NUV5
- Q9NV55
Protein attributes for DNPEP Gene
- Size:
- 475 amino acids
- Molecular mass:
- 52428 Da
- Cofactor:
- Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Quaternary structure:
-
- Tetrahedron-shaped homododecamer built from six homodimers.
- SequenceCaution:
-
- Sequence=BAA91903.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; Sequence=BAA91903.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=BAA92014.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for DNPEP Gene
Selected DME Specific Peptides for DNPEP Gene
- Q9ULA0:
-
- QEELEKGTPEPGPL
- KHEENHRP
- AMHSIRE
- FHKGPVIKVNSKQRYASNAVSE
- RPILRIPHLAIHLQRN
- SADMAHA
- GAHTDSP
- TAFEEAI
- NENFGPN
- QVGVETYGG
Post-translational modifications for DNPEP Gene
Other Protein References for DNPEP Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-DNPEP monoclonal antibody, clone FQS21412
- Creative Biolabs Recombinant Mouse Anti-Human DNPEP Antibody
-
Custom Antibody ServicesOriGene Antibodies for DNPEP
- Novus Biologicals Antibodies for DNPEP
-
Abcam antibodies for DNPEP
- Invitrogen Antibodies for DNPEP (AFLGC-DNPEP)
-
Santa Cruz Biotechnology (SCBT) Antibodies for DNPEP
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for DNPEP
- Origene Custom Protein Services for DNPEP
-
Abcam proteins for DNPEP
Assay Products
- antibodies-online: Show 5 available Aspartyl Aminopeptidase Elisa Kits ranked by validation data
- Compare Top Aspartyl Aminopeptidase Elisa Kits
-
Quality Products:
Domains & Families for DNPEP Gene
Gene Families for DNPEP Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Enzymes
- Plasma proteins
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for DNPEP Gene
- InterPro:
- Blocks:
-
- Aminopeptidase I zinc metalloprotease (M18) signature
- ProtoNet:
Suggested Antigen Peptide Sequences for DNPEP Gene
- GenScript: Design optimal peptide antigens:
-
- Aspartyl aminopeptidase (DNPEP_HUMAN)
- DNPEP protein (Q9BSS9_HUMAN)
- cDNA FLJ11809 fis, clone HEMBA1006309, highly similar to Homo sapiens aspartyl aminopeptidase mRNA (Q9HAC6_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9ULA0- Family:
-
- Belongs to the peptidase M18 family.
Function for DNPEP Gene
Molecular function for DNPEP Gene
- UniProtKB/Swiss-Prot Function:
- Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important role in intracellular protein and peptide metabolism.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.; EC=3.4.11.21; Evidence={ECO:0000269|PubMed:9632644};.
- UniProtKB/Swiss-Prot EnzymeRegulation:
- One of the zinc ions is readily exchangeable with other divalent cations such as manganese, which strongly stimulates the enzymatic activity.
Enzyme Numbers (IUBMB) for DNPEP Gene
Phenotypes From GWAS Catalog for DNPEP Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004177 | aminopeptidase activity | IEA,TAS | 9632644 |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0008233 | peptidase activity | IEA | -- |
| GO:0008237 | metallopeptidase activity | IEA | -- |
| GO:0008270 | zinc ion binding | IEA | -- |
Phenotypes for DNPEP Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for DNPEP
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for DNPEP - Select products 50% OFF >
- * DNPEP CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for DNPEP
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DNPEP
-
Santa Cruz Biotechnology (SCBT) CRISPR for DNPEP
miRNA for DNPEP Gene
- miRTarBase miRNAs that target DNPEP
-
- hsa-miR-140-5p (MIRT007029)
- hsa-miR-218-5p (MIRT440788)
- hsa-miR-5698 (MIRT649175)
- hsa-miR-143-5p (MIRT649176)
- hsa-miR-4430 (MIRT649177)
- hsa-miR-3652 (MIRT649178)
- hsa-miR-760 (MIRT649179)
- hsa-miR-24-3p (MIRT649180)
- hsa-miR-4284 (MIRT649181)
- hsa-miR-122-5p (MIRT649182)
- hsa-miR-504-3p (MIRT649183)
- hsa-miR-3135b (MIRT649184)
- hsa-miR-7158-5p (MIRT649185)
- hsa-miR-6499-3p (MIRT649186)
- hsa-miR-5693 (MIRT649187)
- hsa-miR-3156-3p (MIRT649188)
- hsa-miR-4474-5p (MIRT649189)
- hsa-miR-4755-3p (MIRT649190)
- hsa-miR-532-3p (MIRT649191)
- hsa-miR-554 (MIRT649192)
- hsa-miR-4301 (MIRT649193)
- hsa-miR-484 (MIRT649194)
- hsa-miR-3155b (MIRT649195)
- hsa-miR-3155a (MIRT649196)
- hsa-miR-483-3p (MIRT649197)
- hsa-miR-8057 (MIRT664618)
- hsa-miR-6822-3p (MIRT664619)
- hsa-miR-6504-5p (MIRT664620)
- hsa-miR-3064-5p (MIRT664621)
- hsa-miR-149-5p (MIRT664622)
- hsa-miR-4794 (MIRT664623)
- hsa-miR-664a-5p (MIRT664624)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DNPEP
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Clone Products
- Applied Biological Materials (abm): Clones for DNPEP - Select products 50% OFF >
- * DNPEP as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- Sino Biological Human cDNA Clone for DNPEP
- Addgene plasmids for DNPEP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DNPEP
Cell Line Products
-
Horizon Cell Lines for DNPEP
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for DNPEP Gene
Localization for DNPEP Gene
Subcellular locations from UniProtKB/Swiss-Prot for DNPEP Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| extracellular | 4 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
- Cytosol (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | HDA | 21630459 |
| GO:0005737 | cytoplasm | TAS | -- |
| GO:0005829 | cytosol | IDA | -- |
| GO:0072562 | blood microparticle | HDA | 22516433 |
Pathways & Interactions for DNPEP Gene
Interacting Proteins for DNPEP Gene
Selected Interacting proteins:
Q9ULA0-DNPEP_HUMAN
ENSP00000273075
for DNPEP Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for DNPEP
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006508 | proteolysis | IEA | -- |
| GO:0006518 | peptide metabolic process | TAS | 9632644 |
No data available for Pathways by source and SIGNOR curated interactions for DNPEP Gene
Drugs & Compounds for DNPEP Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Glutamic acid | Approved | Nutra | Agonist, Full agonist, Target | 304 |
Transcripts for DNPEP Gene
mRNA/cDNA for DNPEP Gene
- 8 REFSEQ mRNAs :
- 20 NCBI additional mRNA sequence :
- 21 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000520694 2408 nts (view in UCSC)
- ENST00000273075 2425 nts (view in UCSC)
- ENST00000373972 1578 nts (view in UCSC)
- ENST00000523282 1662 nts (view in UCSC)
- ENST00000373963 1657 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for DNPEP - Select products 50% OFF >
- * DNPEP CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for DNPEP
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DNPEP
-
Santa Cruz Biotechnology (SCBT) CRISPR for DNPEP
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DNPEP
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DNPEP
Clone Products
- Applied Biological Materials (abm): Clones for DNPEP - Select products 50% OFF >
- * DNPEP as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for DNPEP
- Addgene plasmids for DNPEP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DNPEP
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - |
| ExUns: | 15b | ^ | 16a | · | 16b | · | 16c | ^ | 17a | · | 17b |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||
| SP2: | |||||||||||
| SP3: | |||||||||||
| SP4: | |||||||||||
| SP5: | |||||||||||
| SP6: | |||||||||||
| SP7: | |||||||||||
| SP8: | |||||||||||
| SP9: | |||||||||||
| SP10: | |||||||||||
| SP11: |
Relevant External Links for DNPEP Gene
- GeneLoc Exon Structure for
- DNPEP
Expression for DNPEP Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for DNPEP Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DNPEP
SOURCE GeneReport for Unigene cluster for DNPEP Gene:
Hs.258551mRNA Expression by UniProt/SwissProt for DNPEP Gene:
Q9ULA0-DNPEP_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for DNPEP Gene
- Liver(4.6)
- Eye(4.2)
- Nervous system(3.9)
- Intestine(3.2)
- Kidney(3.1)
- Adrenal gland(2.8)
- Thyroid gland(2.8)
- Gall bladder(2.3)
- Lung(2.3)
- Stomach(2.3)
- Muscle(2.3)
- Heart(2.3)
- Blood(2.1)
Primer Products
-
OriGene qPCR primer pairs for DNPEP
-
OriGene qPCR primer pairs and template standards for DNPEP
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for DNPEP Gene
Orthologs for DNPEP Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | DNPEP 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | DNPEP 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | DNPEP 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Dnpep 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Dnpep 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | DNPEP 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | DNPEP 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | DNPEP 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | dnpep 30 |
|
||
| Str.2142 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.20819 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | dnpep 30 31 |
|
OneToOne | |
| zgc55944 30 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.10876 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | dnpp-1 30 31 |
|
OneToOne | |
| F01F1.9 32 |
|
|
|||
| K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0E21297g 30 |
|
||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | APE4 30 31 33 |
|
OneToOne | |
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT5G60160 30 |
|
||
| Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.1803 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os12g0236500 30 |
|
||
| Os.16710 30 |
|
||||
| Barley (Hordeum vulgare) |
Liliopsida | Hv.1571 30 |
|
||
| Wheat (Triticum aestivum) |
Liliopsida | Ta.7128 30 |
|
||
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU00122 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.10534 31 |
|
OneToOne | |
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | aap1 30 |
|
- Species where no ortholog for DNPEP was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Evolution for DNPEP Gene
- ENSEMBL:
- Gene Tree for DNPEP (if available)
- TreeFam:
- Gene Tree for DNPEP (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for DNPEP: view image
Paralogs for DNPEP Gene
No data available for Paralogs for DNPEP Gene
Variants for DNPEP Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1126577 | CNV | deletion | 24896259 |
| nsv834543 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
35.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.01;
60.24% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for DNPEP Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- DNPEP
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DNPEP Gene
Disorders for DNPEP Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| nemaline myopathy 9 |
|
|
| tarsal-carpal coalition syndrome |
|
|
| nemaline myopathy 8 |
|
|
| nemaline myopathy 11, autosomal recessive |
|
|
| nemaline myopathy 10 |
|
|
Search DNPEP in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for DNPEP
No data available for UniProtKB/Swiss-Prot and Genatlas for DNPEP Gene
Publications for DNPEP Gene
- Purification, characterization, and cloning of a cytosolic aspartyl aminopeptidase. (PMID: 9632644) Wilk S … Magnusson RP (The Journal of biological chemistry 1998) 2 3 4 23
- Structure of human aspartyl aminopeptidase complexed with substrate analogue: insight into catalytic mechanism, substrate specificity and M18 peptidase family. (PMID: 22720794) Chaikuad A … Yue WW (BMC structural biology 2012) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Identification of histidine residues important in the catalysis and structure of aspartyl aminopeptidase. (PMID: 12413488) Wilk S … Magnusson RP (Archives of biochemistry and biophysics 2002) 3 23
ExternalLinks
Products for DNPEP Gene
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- OriGene qPCR primer pairs for DNPEP
- OriGene qPCR primer pairs and template standards for DNPEP
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- Abcam antibodies for DNPEP
- Abcam proteins for DNPEP
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- Taconic Biosciences Mouse Models for DNPEP
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for DNPEP (AFLGC-DNPEP)
- VectorBuilder Custom and pre-made DNA vectors for DNPEP (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for DNPEP (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for DNPEP (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for DNPEP CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for DNPEP
- Addgene plasmids for DNPEP
- antibodies-online: Show 16 available Aspartyl Aminopeptidase Antibodies ranked by validation data
- Compare Top Aspartyl Aminopeptidase Antibodies
- antibodies-online: Show 5 available Aspartyl Aminopeptidase Elisa Kits ranked by validation data
- Compare Top Aspartyl Aminopeptidase Elisa Kits
- Quality Products:
- antibodies-online: Show 7 available Aspartyl Aminopeptidase Proteins ranked by validation data
- Compare Top Aspartyl Aminopeptidase Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for DNPEP
- Search Santa Cruz Biotechnology (SCBT) for DNPEP siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for DNPEP
- Horizon Cell Lines for DNPEP
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DNPEP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DNPEP
- Search GeneCopoeia for miRNA 3'UTR Target clone products for DNPEP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DNPEP
Sources for DNPEP Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB