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Aliases for DNAJC5G Gene

Aliases for DNAJC5G Gene

  • DnaJ Heat Shock Protein Family (Hsp40) Member C5 Gamma 2 3 5
  • DnaJ (Hsp40) Homolog, Subfamily C, Member 5 Gamma 2 3
  • Cysteine String Protein-Gamma 3 4
  • CSP-Gamma 3 4
  • DnaJ Homolog Subfamily C Member 5G 3
  • Gamma-Cysteine String Protein 3
  • Gamma-CSP 3

External Ids for DNAJC5G Gene

Previous GeneCards Identifiers for DNAJC5G Gene

  • GC02P027473
  • GC02P027412
  • GC02P027498

Summaries for DNAJC5G Gene

GeneCards Summary for DNAJC5G Gene

DNAJC5G (DnaJ Heat Shock Protein Family (Hsp40) Member C5 Gamma) is a Protein Coding gene. Among its related pathways are Protein processing in endoplasmic reticulum. An important paralog of this gene is DNAJC5.

Additional gene information for DNAJC5G Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNAJC5G Gene

Genomics for DNAJC5G Gene

GeneHancer (GH) Regulatory Elements for DNAJC5G Gene

Promoters and enhancers for DNAJC5G Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J027275 Promoter 0.5 EPDnew 650.7 0.0 -3 0.1 SLC30A3 DNAJC5G CAD
GH02J027320 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.1 +47.3 47257 4.2 MLX YBX1 DMAP1 YY1 SLC30A9 E2F8 ZNF143 SP3 NFYC SSRP1 MPV17 PIR47141 ATRAID AGBL5 DNAJC5G SLC30A3 SNX17 ZNF513 PPM1G SLC5A6
GH02J027090 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE dbSUPER 10.2 -181.5 -181506 6.6 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF766 ZNF143 KHK AGBL5 ABHD1 CGREF1 ATRAID SLC5A6 CAD PRR30 TCF23 PREB
GH02J027169 Enhancer 1.2 Ensembl ENCODE 10.5 -104.2 -104153 2.9 FOXA2 MLX ARID4B SIN3A DMAP1 YY1 ZNF143 SP5 ZHX2 MXD4 ATRAID GTF3C2 TCF23 PRR30 PREB SLC5A6 ABHD1 CAD SLC30A3 DNAJC5G
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around DNAJC5G on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the DNAJC5G gene promoter:
  • Bach2
  • LCR-F1
  • Nkx2-5
  • Arnt
  • E47
  • CREB
  • deltaCREB
  • NF-1
  • POU3F2
  • POU3F2 (N-Oct-5a)

Genomic Locations for DNAJC5G Gene

Genomic Locations for DNAJC5G Gene
6,079 bases
Plus strand
6,079 bases
Plus strand

Genomic View for DNAJC5G Gene

Genes around DNAJC5G on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DNAJC5G Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DNAJC5G Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DNAJC5G Gene

Proteins for DNAJC5G Gene

  • Protein details for DNAJC5G Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    DnaJ homolog subfamily C member 5G
    Protein Accession:
    Secondary Accessions:
    • B4DY29
    • Q53SY5
    • Q8IYQ4
    • Q96RJ8

    Protein attributes for DNAJC5G Gene

    189 amino acids
    Molecular mass:
    21433 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for DNAJC5G Gene


neXtProt entry for DNAJC5G Gene

Post-translational modifications for DNAJC5G Gene

No data available for DME Specific Peptides for DNAJC5G Gene

Domains & Families for DNAJC5G Gene

Gene Families for DNAJC5G Gene

Protein Domains for DNAJC5G Gene

Suggested Antigen Peptide Sequences for DNAJC5G Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DNAJC5G: view

No data available for UniProtKB/Swiss-Prot for DNAJC5G Gene

Function for DNAJC5G Gene

genes like me logo Genes that share phenotypes with DNAJC5G: view

Animal Models for DNAJC5G Gene

MGI Knock Outs for DNAJC5G:

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for DNAJC5G Gene

Localization for DNAJC5G Gene

Subcellular locations from UniProtKB/Swiss-Prot for DNAJC5G Gene

Membrane; Lipid-anchor.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DNAJC5G gene
Compartment Confidence
cytosol 3
plasma membrane 1
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for DNAJC5G Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with DNAJC5G: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for DNAJC5G Gene

Pathways & Interactions for DNAJC5G Gene

genes like me logo Genes that share pathways with DNAJC5G: view

Pathways by source for DNAJC5G Gene

1 KEGG pathway for DNAJC5G Gene

Interacting Proteins for DNAJC5G Gene

Gene Ontology (GO) - Biological Process for DNAJC5G Gene


No data available for SIGNOR curated interactions for DNAJC5G Gene

Drugs & Compounds for DNAJC5G Gene

No Compound Related Data Available

Transcripts for DNAJC5G Gene

mRNA/cDNA for DNAJC5G Gene

(7) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(15) Selected AceView cDNA sequences:
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DNAJC5G Gene

DnaJ (Hsp40) homolog, subfamily C, member 5 gamma:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC5G Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4

Relevant External Links for DNAJC5G Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DNAJC5G Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DNAJC5G Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for DNAJC5G Gene

This gene is overexpressed in Testis (x26.2) and Brain - Cortex (x4.9).

Protein differential expression in normal tissues from HIPED for DNAJC5G Gene

This gene is overexpressed in Adipocyte (46.2) and Blymphocyte (22.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for DNAJC5G Gene

Protein tissue co-expression partners for DNAJC5G Gene

NURSA nuclear receptor signaling pathways regulating expression of DNAJC5G Gene:


SOURCE GeneReport for Unigene cluster for DNAJC5G Gene:


mRNA Expression by UniProt/SwissProt for DNAJC5G Gene:

Tissue specificity: Testis specific.
genes like me logo Genes that share expression patterns with DNAJC5G: view

No data available for Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DNAJC5G Gene

Orthologs for DNAJC5G Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for DNAJC5G Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia DNAJC5G 34 33
  • 98.06 (n)
(Canis familiaris)
Mammalia DNAJC5G 34 33
  • 86.29 (n)
(Bos Taurus)
Mammalia DNAJC5G 34 33
  • 80.81 (n)
(Rattus norvegicus)
Mammalia Dnajc5g 33
  • 76.71 (n)
(Mus musculus)
Mammalia Dnajc5g 16 34 33
  • 75.76 (n)
(Monodelphis domestica)
Mammalia DNAJC5G 34
  • 56 (a)
(Ornithorhynchus anatinus)
Mammalia DNAJC5G 34
  • 49 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 25 (a)
(Danio rerio)
Actinopterygii dnajc5ga 34
  • 41 (a)
dnajc5gb 34
  • 39 (a)
fruit fly
(Drosophila melanogaster)
Insecta Csp 34
  • 33 (a)
(Caenorhabditis elegans)
Secernentea dnj-14 34
  • 32 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SIS1 34
  • 13 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8441 34
  • 37 (a)
Species where no ortholog for DNAJC5G was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for DNAJC5G Gene

Gene Tree for DNAJC5G (if available)
Gene Tree for DNAJC5G (if available)
Evolutionary constrained regions (ECRs) for DNAJC5G: view image

Paralogs for DNAJC5G Gene

Paralogs for DNAJC5G Gene

(11) SIMAP similar genes for DNAJC5G Gene using alignment to 4 proteins:

  • B4DY29_HUMAN
  • C9J078_HUMAN
genes like me logo Genes that share paralogs with DNAJC5G: view

Variants for DNAJC5G Gene

Sequence variations from dbSNP and Humsavar for DNAJC5G Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000082722 -- 27,273,662(+) C/T upstream_transcript_variant
rs1000115953 -- 27,280,272(+) A/G intron_variant
rs1000617111 -- 27,279,454(+) T/C intron_variant
rs1000866538 -- 27,279,023(+) G/ intron_variant
rs1000981955 -- 27,279,198(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for DNAJC5G Gene

Variant ID Type Subtype PubMed ID
nsv833614 CNV gain 17160897
esv3326859 CNV insertion 20981092

Variation tolerance for DNAJC5G Gene

Residual Variation Intolerance Score: 74.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.50; 55.33% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for DNAJC5G Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DNAJC5G Gene

Disorders for DNAJC5G Gene

Additional Disease Information for DNAJC5G

No disorders were found for DNAJC5G Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DNAJC5G Gene

Publications for DNAJC5G Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for DNAJC5G Gene

Sources for DNAJC5G Gene

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