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Aliases for DNAJB3 Gene

Aliases for DNAJB3 Gene

  • DnaJ Heat Shock Protein Family (Hsp40) Member B3 2 3 5
  • DnaJ (Hsp40) Homolog, Subfamily B, Member 3 2 3
  • HCG3 3 4
  • DnaJ Homolog Subfamily B Member 3 3

External Ids for DNAJB3 Gene

Previous GeneCards Identifiers for DNAJB3 Gene

  • GC02U901524
  • GC02M234318
  • GC02M234651
  • GC02M226451

Summaries for DNAJB3 Gene

GeneCards Summary for DNAJB3 Gene

DNAJB3 (DnaJ Heat Shock Protein Family (Hsp40) Member B3) is a Protein Coding gene.

UniProtKB/Swiss-Prot for DNAJB3 Gene

  • May operate as a co-chaperone of the male germ cell- and haploid stage-specific Hsp70 proteins.

Additional gene information for DNAJB3 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNAJB3 Gene

Genomics for DNAJB3 Gene

GeneHancer (GH) Regulatory Elements for DNAJB3 Gene

Promoters and enhancers for DNAJB3 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I233745 Enhancer 0.9 ENCODE 550.8 -1.6 -1570 1 FOXA2 MLX ARID4B DMAP1 ETS1 YY1 TCF12 ATF7 RXRA SP5 DNAJB3 UGT1A2P LOC100286922 UGT1A6 UGT1A3 UGT1A4 UGT1A5 UGT1A7 UGT1A9 UGT1A10
GH02I233763 Enhancer 0.9 FANTOM5 ENCODE 5.3 -20.4 -20431 1.6 FOXA2 TAF1 MAX RAD21 YY1 ZFHX2 HNF4G EGR2 RXRA REST UGT1A4 UGT1A6 LOC100286922 DNAJB3 UGT1A1 MROH2A UGT1A3 UGT1A5 UGT1A7 UGT1A9
GH02I233757 Enhancer 0.4 ENCODE 5.3 -14.5 -14467 1.8 NFYC PPARG MIXL1 UGT1A1 UGT1A6 LOC100286922 USP40 DNAJB3 PIR60361 UGT1A3 UGT1A4 UGT1A5 UGT1A7
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around DNAJB3 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the DNAJB3 gene promoter:

Genomic Locations for DNAJB3 Gene

Genomic Locations for DNAJB3 Gene
1,266 bases
Minus strand

Genomic View for DNAJB3 Gene

Genes around DNAJB3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DNAJB3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DNAJB3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DNAJB3 Gene

Proteins for DNAJB3 Gene

  • Protein details for DNAJB3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    DnaJ homolog subfamily B member 3
    Protein Accession:

    Protein attributes for DNAJB3 Gene

    145 amino acids
    Molecular mass:
    16559 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for DNAJB3 Gene

neXtProt entry for DNAJB3 Gene

Post-translational modifications for DNAJB3 Gene

No Post-translational modifications

Other Protein References for DNAJB3 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for DNAJB3 Gene

Domains & Families for DNAJB3 Gene

Gene Families for DNAJB3 Gene

Protein Domains for DNAJB3 Gene

Suggested Antigen Peptide Sequences for DNAJB3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DNAJB3: view

No data available for UniProtKB/Swiss-Prot for DNAJB3 Gene

Function for DNAJB3 Gene

Molecular function for DNAJB3 Gene

UniProtKB/Swiss-Prot Function:
May operate as a co-chaperone of the male germ cell- and haploid stage-specific Hsp70 proteins.

Phenotypes From GWAS Catalog for DNAJB3 Gene

genes like me logo Genes that share phenotypes with DNAJB3: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DNAJB3 Gene

Localization for DNAJB3 Gene

Gene Ontology (GO) - Cellular Components for DNAJB3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome HDA 23376485
genes like me logo Genes that share ontologies with DNAJB3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for DNAJB3 Gene

Pathways & Interactions for DNAJB3 Gene

SuperPathways for DNAJB3 Gene

No Data Available

Interacting Proteins for DNAJB3 Gene

Selected Interacting proteins: Q8WWF6-DNJB3_HUMAN for DNAJB3 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for DNAJB3 Gene


No data available for Pathways by source and SIGNOR curated interactions for DNAJB3 Gene

Drugs & Compounds for DNAJB3 Gene

No Compound Related Data Available

Transcripts for DNAJB3 Gene

mRNA/cDNA for DNAJB3 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DNAJB3 Gene

DnaJ (Hsp40) homolog, subfamily B, member 3:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for DNAJB3 Gene

No ASD Table

Relevant External Links for DNAJB3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DNAJB3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DNAJB3 Gene

mRNA differential expression in normal tissues according to GTEx for DNAJB3 Gene

This gene is overexpressed in Testis (x47.6).

Protein differential expression in normal tissues from HIPED for DNAJB3 Gene

This gene is overexpressed in Heart (48.7) and Peripheral blood mononuclear cells (20.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for DNAJB3 Gene

Protein tissue co-expression partners for DNAJB3 Gene

NURSA nuclear receptor signaling pathways regulating expression of DNAJB3 Gene:


SOURCE GeneReport for Unigene cluster for DNAJB3 Gene:


mRNA Expression by UniProt/SwissProt for DNAJB3 Gene:

Tissue specificity: Expressed in sperm (at protein level).
genes like me logo Genes that share expression patterns with DNAJB3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DNAJB3 Gene

Orthologs for DNAJB3 Gene

Evolution for DNAJB3 Gene

Gene Tree for DNAJB3 (if available)
Gene Tree for DNAJB3 (if available)

No data available for Orthologs for DNAJB3 Gene

Paralogs for DNAJB3 Gene

(18) SIMAP similar genes for DNAJB3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with DNAJB3: view

No data available for Paralogs for DNAJB3 Gene

Variants for DNAJB3 Gene

Sequence variations from dbSNP and Humsavar for DNAJB3 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1002862654 -- 233,744,129(-) A/C upstream_transcript_variant
rs1002936325 -- 233,744,376(-) C/T upstream_transcript_variant
rs1003194784 -- 233,745,429(-) A/G upstream_transcript_variant
rs1003270220 -- 233,745,788(-) G/T upstream_transcript_variant
rs1003987688 -- 233,744,443(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for DNAJB3 Gene

Variant ID Type Subtype PubMed ID
nsv519815 CNV loss 19592680
nsv514125 CNV loss 21397061
nsv498958 CNV loss 21111241
nsv433211 CNV loss 18776910
nsv3215 CNV deletion 18451855
nsv1013712 CNV loss 25217958
esv3594681 CNV gain 21293372
esv3594680 CNV loss 21293372
esv2760613 CNV loss 21179565
esv25622 CNV loss 19812545
esv2422005 CNV deletion 20811451
dgv769e199 CNV deletion 23128226

Additional Variant Information for DNAJB3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for DNAJB3 Gene

Disorders for DNAJB3 Gene

Additional Disease Information for DNAJB3

No disorders were found for DNAJB3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DNAJB3 Gene

Publications for DNAJB3 Gene

  1. Novel linkage disequilibrium clustering algorithm identifies new lupus genes on meta-analysis of GWAS datasets. (PMID: 28246883) Saeed M (Immunogenetics 2017) 3 58
  2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M … Moll S (Journal of proteomics 2013) 3 58
  3. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PMID: 23824909) Chen Y … Ge F (Molecular & cellular proteomics : MCP 2013) 3 58
  4. Identification of HYPK-interacting proteins reveals involvement of HYPK in regulating cell growth, cell cycle, unfolded protein response and cell death. (PMID: 23272104) Choudhury KR … Bhattacharyya NP (PloS one 2012) 3 58
  5. Structure of msj-1 gene in mice and humans: a possible role in the regulation of male reproduction. (PMID: 18184612) Meccariello R … Fasano S (General and comparative endocrinology 2008) 4 58

Products for DNAJB3 Gene

Sources for DNAJB3 Gene

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