This gene encodes the heavy chain subunit of axonemal dynein, a large multi-subunit molecular motor. Axonemal dynein attaches to microtubules and hydrolyzes ATP to mediate the movement of cilia and flagella. The gene expresses at least two transcript variants; additional variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul... See more...

Aliases for DNAH9 Gene

Aliases for DNAH9 Gene

  • Dynein Axonemal Heavy Chain 9 2 3 5
  • Dynein, Axonemal, Heavy Polypeptide 9 2 3
  • Axonemal Beta Dynein Heavy Chain 9 3 4
  • Dynein Heavy Chain 9, Axonemal 3 4
  • Ciliary Dynein Heavy Chain 9 3 4
  • KIAA0357 2 4
  • DNAH17L 3 4
  • Dnahc9 2 3
  • DNEL1 3 4
  • HL-20 2 3
  • DYH9 2 3
  • HL20 2 3
  • Dynein, Axonemal, Heavy Polypeptide 17-Like 2
  • DNAH9 Variant Protein 3
  • EC 3.1.26.3 50
  • EC 2.1.3.2 50
  • CILD40 3
  • DNAH9 5
  • DNAL1 2

External Ids for DNAH9 Gene

Previous HGNC Symbols for DNAH9 Gene

  • DNAH17L

Previous GeneCards Identifiers for DNAH9 Gene

  • GC17P011867
  • GC17P012616
  • GC17P011444
  • GC17P011702
  • GC17P011442
  • GC17P011501

Summaries for DNAH9 Gene

Entrez Gene Summary for DNAH9 Gene

  • This gene encodes the heavy chain subunit of axonemal dynein, a large multi-subunit molecular motor. Axonemal dynein attaches to microtubules and hydrolyzes ATP to mediate the movement of cilia and flagella. The gene expresses at least two transcript variants; additional variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

GeneCards Summary for DNAH9 Gene

DNAH9 (Dynein Axonemal Heavy Chain 9) is a Protein Coding gene. Diseases associated with DNAH9 include Ciliary Dyskinesia, Primary, 40 and Dextrocardia With Situs Inversus. Among its related pathways are Pathways of neurodegeneration - multiple diseases. Gene Ontology (GO) annotations related to this gene include ATPase activity and motor activity. An important paralog of this gene is DNAH17.

UniProtKB/Swiss-Prot Summary for DNAH9 Gene

  • Force generating protein required for cilia beating in respiratory epithelia (PubMed:30471717, PubMed:30471718). Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

Gene Wiki entry for DNAH9 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DNAH9 Gene

Genomics for DNAH9 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for DNAH9 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J011598 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE CraniofacialAtlas 250.7 +0.3 331 1.6 SIN3A SAP130 SP1 NFYC RFX1 TFAP4 CSDE1 HDAC1 ARID4B ATF1 DNAH9 HSALNG0114591 MAP2K4
GH17J011590 Enhancer 0.2 FANTOM5 14.4 -7.9 -7942 0.2 piR-58821 DNAH9 HSALNG0114591 SHISA6
GH17J011781 Enhancer 0.2 FANTOM5 3.9 +183.6 183642 0.2 DNAH9 piR-45035-084 HSALNG0114598 MAP2K4
GH17J011971 Enhancer 0.2 FANTOM5 2.6 +373.2 373205 0 piR-48950-070 piR-41245-103 DNAH9 piR-50437-268 ENSG00000266368 MAP2K4 ZNF18
GH17J011608 Enhancer 0.9 Ensembl ENCODE 0.4 +10.1 10130 1.2 ATF3 NFIC YY1 FOXA2 SMAD4 RXRA SAP130 ZBTB33 JUND TAL1 HSALNG0114596 HSALNG0114591 DNAH9 MAP2K4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around DNAH9 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for DNAH9

Top Transcription factor binding sites by QIAGEN in the DNAH9 gene promoter:
  • AML1a
  • AP-2alpha
  • AP-2alphaA
  • AP-2beta
  • AP-2gamma
  • C/EBPalpha
  • E47
  • Hand1
  • Nkx6-1
  • Pax-5

Genomic Locations for DNAH9 Gene

Latest Assembly
chr17:11,598,470-11,970,168
(GRCh38/hg38)
Size:
371,699 bases
Orientation:
Plus strand

Previous Assembly
chr17:11,501,787-11,873,065
(GRCh37/hg19 by Entrez Gene)
Size:
371,279 bases
Orientation:
Plus strand

chr17:11,501,748-11,873,065
(GRCh37/hg19 by Ensembl)
Size:
371,318 bases
Orientation:
Plus strand

Genomic View for DNAH9 Gene

Genes around DNAH9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DNAH9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DNAH9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DNAH9 Gene

Proteins for DNAH9 Gene

  • Protein details for DNAH9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NYC9-DYH9_HUMAN
    Recommended name:
    Dynein heavy chain 9, axonemal
    Protein Accession:
    Q9NYC9
    Secondary Accessions:
    • A2VCQ8
    • O15064
    • O95494
    • Q9NQ28

    Protein attributes for DNAH9 Gene

    Size:
    4486 amino acids
    Molecular mass:
    511877 Da
    Quaternary structure:
    • Consists of at least two heavy chains and a number of intermediate and light chains. Interacts with ODAD1 (PubMed:30471718).

    Alternative splice isoforms for DNAH9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DNAH9 Gene

Selected DME Specific Peptides for DNAH9 Gene

Q9NYC9:
  • SVILEQV
  • RKLGYTF

Post-translational modifications for DNAH9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Domains & Families for DNAH9 Gene

Gene Families for DNAH9 Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for DNAH9 Gene

Suggested Antigen Peptide Sequences for DNAH9 Gene

GenScript: Design optimal peptide antigens:
  • Dynein, axonemal, heavy polypeptide 9, isoform CRA_a (A2VCN3_HUMAN)
  • DNAH9 protein (A8KAY3_HUMAN)
  • cDNA FLJ54811, highly similar to Ciliary dynein heavy chain 9 (B7Z7H0_HUMAN)
  • Ciliary dynein heavy chain 9 (DYH9_HUMAN)
  • Dynein heavy chain (Q92865_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9NYC9

UniProtKB/Swiss-Prot:

DYH9_HUMAN :
  • Dynein heavy chains probably consist of an N-terminal stem (which binds cargo and interacts with other dynein components), and the head or motor domain. The motor contains six tandemly-linked AAA domains in the head, which form a ring. A stalk-like structure (formed by two of the coiled coil domains) protrudes between AAA 4 and AAA 5 and terminates in a microtubule-binding site. A seventh domain may also contribute to this ring; it is not clear whether the N-terminus or the C-terminus forms this extra domain. There are four well-conserved and two non-conserved ATPase sites, one per AAA domain. Probably only one of these (within AAA 1) actually hydrolyzes ATP, the others may serve a regulatory function.
  • Belongs to the dynein heavy chain family.
Domain:
  • Dynein heavy chains probably consist of an N-terminal stem (which binds cargo and interacts with other dynein components), and the head or motor domain. The motor contains six tandemly-linked AAA domains in the head, which form a ring. A stalk-like structure (formed by two of the coiled coil domains) protrudes between AAA 4 and AAA 5 and terminates in a microtubule-binding site. A seventh domain may also contribute to this ring; it is not clear whether the N-terminus or the C-terminus forms this extra domain. There are four well-conserved and two non-conserved ATPase sites, one per AAA domain. Probably only one of these (within AAA 1) actually hydrolyzes ATP, the others may serve a regulatory function.
Family:
  • Belongs to the dynein heavy chain family.
genes like me logo Genes that share domains with DNAH9: view

Function for DNAH9 Gene

Molecular function for DNAH9 Gene

UniProtKB/Swiss-Prot Function:
Force generating protein required for cilia beating in respiratory epithelia (PubMed:30471717, PubMed:30471718). Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

Enzyme Numbers (IUBMB) for DNAH9 Gene

Phenotypes From GWAS Catalog for DNAH9 Gene

Gene Ontology (GO) - Molecular Function for DNAH9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003774 motor activity IEA --
GO:0003777 microtubule motor activity IEA --
GO:0005515 protein binding IPI 30471718
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with DNAH9: view
genes like me logo Genes that share phenotypes with DNAH9: view

Human Phenotype Ontology for DNAH9 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

miRNA for DNAH9 Gene

miRTarBase miRNAs that target DNAH9

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DNAH9

No data available for Animal Models , Transcription Factor Targets and HOMER Transcription for DNAH9 Gene

Localization for DNAH9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DNAH9 Gene

Cytoplasm, cytoskeleton, cilium axoneme. Note=Found in the distal portion of ciliary axoneme. {ECO:0000269 PubMed:30471717, ECO:0000269 PubMed:30471718}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DNAH9 gene
Compartment Confidence
cytoskeleton 5
cytosol 2
plasma membrane 1
extracellular 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for DNAH9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005856 cytoskeleton IEA --
GO:0005874 microtubule IEA --
GO:0005929 cilium IEA --
GO:0005930 axoneme IBA,IDA 11104725
genes like me logo Genes that share ontologies with DNAH9: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for DNAH9 Gene

Pathways & Interactions for DNAH9 Gene

genes like me logo Genes that share pathways with DNAH9: view

Pathways by source for DNAH9 Gene

Gene Ontology (GO) - Biological Process for DNAH9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003341 cilium movement IBA,IMP 30471717
GO:0007018 microtubule-based movement IBA 21873635
GO:0030030 cell projection organization IEA --
genes like me logo Genes that share ontologies with DNAH9: view

No data available for SIGNOR curated interactions for DNAH9 Gene

Drugs & Compounds for DNAH9 Gene

No Compound Related Data Available

Transcripts for DNAH9 Gene

mRNA/cDNA for DNAH9 Gene

2 REFSEQ mRNAs :
14 NCBI additional mRNA sequence :
15 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DNAH9

Alternative Splicing Database (ASD) splice patterns (SP) for DNAH9 Gene

No ASD Table

Relevant External Links for DNAH9 Gene

GeneLoc Exon Structure for
DNAH9

Expression for DNAH9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for DNAH9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for DNAH9 Gene

This gene is overexpressed in Brain - Hypothalamus (x5.7), Brain - Caudate (basal ganglia) (x5.1), Brain - Hippocampus (x4.4), Testis (x4.1), and Brain - Nucleus accumbens (basal ganglia) (x4.0).

Protein differential expression in normal tissues from HIPED for DNAH9 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (61.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for DNAH9 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DNAH9

SOURCE GeneReport for Unigene cluster for DNAH9 Gene:

Hs.567259

mRNA Expression by UniProt/SwissProt for DNAH9 Gene:

Q9NYC9-DYH9_HUMAN
Tissue specificity: Expressed in upper and lower respiratory airway epithelia (at protein level). Not detected in spermatozoa (at protein level) (PubMed:31178125).

Evidence on tissue expression from TISSUES for DNAH9 Gene

  • Lung(4.4)
  • Nervous system(4.3)
genes like me logo Genes that share expression patterns with DNAH9: view

Primer products for research

No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for DNAH9 Gene

Orthologs for DNAH9 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for DNAH9 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia DNAH9 29 30
  • 99.35 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia DNAH9 29 30
  • 86.97 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia DNAH9 29 30
  • 85.92 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Dnah9 29 16 30
  • 85.45 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Dnah9 29
  • 85.23 (n)
Oppossum
(Monodelphis domestica)
Mammalia DNAH9 30
  • 79 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 30
  • 79 (a)
ManyToMany
-- 30
  • 40 (a)
ManyToMany
-- 30
  • 37 (a)
ManyToMany
Chicken
(Gallus gallus)
Aves DNAH9 29 30
  • 75.31 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia DNAH9 30
  • 77 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia dnah9 29
  • 73.04 (n)
African clawed frog
(Xenopus laevis)
Amphibia dnah9-A 29
Zebrafish
(Danio rerio)
Actinopterygii DNAH9 30
  • 78 (a)
OneToOne
dnahc11 29
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.12799 29
Fruit Fly
(Drosophila melanogaster)
Insecta kl-5 31
  • 86 (a)
Dhc93AB 29 31
  • 60.51 (n)
kl-2 31
  • 30 (a)
Dhc64C 31
  • 27 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010435 29
  • 60.04 (n)
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes DYN1 30
  • 20 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 30
  • 64 (a)
ManyToMany
Species where no ortholog for DNAH9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for DNAH9 Gene

ENSEMBL:
Gene Tree for DNAH9 (if available)
TreeFam:
Gene Tree for DNAH9 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for DNAH9: view image
Alliance of Genome Resources:
Additional Orthologs for DNAH9

Paralogs for DNAH9 Gene

(16) SIMAP similar genes for DNAH9 Gene using alignment to 9 proteins:

  • DYH9_HUMAN
  • A2VCN3_HUMAN
  • A8KAY3_HUMAN
  • E7EP17_HUMAN
  • J3QLM9_HUMAN
  • J3QQK8_HUMAN
  • K7EMX3_HUMAN
  • K7EP21_HUMAN
  • L8E799_HUMAN
genes like me logo Genes that share paralogs with DNAH9: view

Variants for DNAH9 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for DNAH9 Gene

SNP ID Clinical significance and condition Chr 17 pos Variation AA Info Type
1029327 Likely Pathogenic: Ciliary dyskinesia, primary, 40 11,961,948(+) C/T
NM_001372.4(DNAH9):c.12925C>T (p.Arg4309Ter)
NONSENSE
977541 Uncertain Significance: Primary ciliary dyskinesia 11,669,406(+) C/T
NM_001372.4(DNAH9):c.2965C>T (p.Arg989Trp)
MISSENSE
977570 Uncertain Significance: Primary ciliary dyskinesia 11,679,930(+) T/C
NM_001372.4(DNAH9):c.3527T>C (p.Leu1176Pro)
MISSENSE
977571 Likely Pathogenic: Primary ciliary dyskinesia 11,822,456(+) CCT/C
NM_001372.4(DNAH9):c.8870_8871del (p.Pro2957fs)
FRAMESHIFT
977572 Uncertain Significance: Primary ciliary dyskinesia 11,617,557(+) T/C
NM_001372.4(DNAH9):c.1051T>C (p.Ser351Pro)
MISSENSE

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for DNAH9 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for DNAH9 Gene

Variant ID Type Subtype PubMed ID
dgv1417n106 CNV deletion 24896259
esv1227452 CNV insertion 17803354
esv1254302 CNV deletion 17803354
esv1274728 CNV deletion 17803354
esv2636140 CNV deletion 19546169
esv2663712 CNV deletion 23128226
esv2676335 CNV deletion 23128226
esv2715650 CNV deletion 23290073
esv2715652 CNV deletion 23290073
esv2715653 CNV deletion 23290073
esv2715654 CNV deletion 23290073
esv2715655 CNV deletion 23290073
esv2715656 CNV deletion 23290073
esv2715657 CNV deletion 23290073
esv2761946 CNV gain 21179565
esv3161 CNV loss 18987735
esv3363433 CNV insertion 20981092
esv3378005 CNV insertion 20981092
esv3554143 CNV deletion 23714750
esv3554149 CNV deletion 23714750
esv3639956 CNV loss 21293372
esv3639960 CNV loss 21293372
nsv1069672 CNV deletion 25765185
nsv1071372 CNV deletion 25765185
nsv1116188 CNV deletion 24896259
nsv1131299 CNV deletion 24896259
nsv1982 CNV insertion 18451855
nsv954536 CNV deletion 24416366
nsv954564 CNV deletion 24416366

Variation tolerance for DNAH9 Gene

Residual Variation Intolerance Score: 98.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 23.18; 99.52% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for DNAH9 Gene

Human Gene Mutation Database (HGMD)
DNAH9
SNPedia medical, phenotypic, and genealogical associations of SNPs for
DNAH9
Leiden Open Variation Database (LOVD)
DNAH9

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DNAH9 Gene

Disorders for DNAH9 Gene

MalaCards: The human disease database

(19) MalaCards diseases for DNAH9 Gene - From: OMI, CVR, GTR, ORP, SWI, COP, and GCD

Disorder Aliases PubMed IDs
ciliary dyskinesia, primary, 40
  • cild40
dextrocardia with situs inversus
  • situs inversus totalis
visceral heterotaxy
  • heterotaxia
primary ciliary dyskinesia
  • ciliary motility disorder
situs inversus
  • complete transposition
- elite association - COSMIC cancer census association via MalaCards
Search DNAH9 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

DYH9_HUMAN
  • Ciliary dyskinesia, primary, 40 (CILD40) [MIM:618300]: A form of primary ciliary dyskinesia, a disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia. Some patients exhibit randomization of left-right body asymmetry and situs inversus. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. CILD40 inheritance is autosomal recessive. {ECO:0000269 PubMed:30471717, ECO:0000269 PubMed:30471718}. Note=The disease is caused by variants affecting the gene represented in this entry.

Additional Disease Information for DNAH9

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with DNAH9: view

No data available for Genatlas for DNAH9 Gene

Publications for DNAH9 Gene

  1. Axonemal beta heavy chain dynein DNAH9: cDNA sequence, genomic structure, and investigation of its role in primary ciliary dyskinesia. (PMID: 11247663) Bartoloni L … Antonarakis SE (Genomics 2001) 2 3 4 22
  2. Recessive DNAH9 Loss-of-Function Mutations Cause Laterality Defects and Subtle Respiratory Ciliary-Beating Defects. (PMID: 30471718) Loges NT … Schmidts M (American journal of human genetics 2018) 3 4 72
  3. Mutations in Outer Dynein Arm Heavy Chain DNAH9 Cause Motile Cilia Defects and Situs Inversus. (PMID: 30471717) Fassad MR … Mitchison HM (American journal of human genetics 2018) 3 4 72
  4. Characterization of an axonemal dynein heavy chain expressed early in airway epithelial ciliogenesis. (PMID: 11104725) Reed W … Collier AM (American journal of respiratory cell and molecular biology 2000) 3 4 22
  5. Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia. (PMID: 31178125) Whitfield M … Legendre M (American journal of human genetics 2019) 3 4

Products for DNAH9 Gene

Sources for DNAH9 Gene