Aliases for DNAH7 Gene
External Ids for DNAH7 Gene
Previous GeneCards Identifiers for DNAH7 Gene
DNAH7 is a component of the inner dynein arm of ciliary axonemes (Zhang et al., 2002 [PubMed 11877439]).[supplied by OMIM, Mar 2008]
GeneCards Summary for DNAH7 Gene
DNAH7 (Dynein Axonemal Heavy Chain 7) is a Protein Coding gene. Diseases associated with DNAH7 include Basal Ganglia Disease and Visual Epilepsy. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. Gene Ontology (GO) annotations related to this gene include calcium ion binding and microtubule motor activity. An important paralog of this gene is DNAH3.
UniProtKB/Swiss-Prot for DNAH7 Gene
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity).