DMAP1 Gene (Protein Coding)

DNA Methyltransferase 1 Associated Protein 1

GC01P044214
GIFtS:
37
This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, provid... See more...

Aliases for DMAP1 Gene

Aliases for DMAP1 Gene

  • DNA Methyltransferase 1 Associated Protein 1 2 3 5
  • DNMAP1 2 3 4
  • DNA Methyltransferase 1-Associated Protein 1 3 4
  • KIAA1425 2 4
  • DNMTAP1 2 3
  • MEAF2 2 3
  • EAF2 2 3
  • SWC4 2 3
  • DNMT1 Associated Protein 1 3
  • DNMT1-Associated Protein 1 4
  • FLJ11543 2
  • DMAP1 5

External Ids for DMAP1 Gene

Previous GeneCards Identifiers for DMAP1 Gene

  • GC01U990334
  • GC01P043680
  • GC01P044108
  • GC01P044092
  • GC01P044348
  • GC01P044451
  • GC01P044680
  • GC01P042792

Summaries for DMAP1 Gene

Entrez Gene Summary for DMAP1 Gene

  • This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

GeneCards Summary for DMAP1 Gene

DMAP1 (DNA Methyltransferase 1 Associated Protein 1) is a Protein Coding gene. Diseases associated with DMAP1 include Cerebellar Ataxia, Deafness, And Narcolepsy, Autosomal Dominant and Atrophy Of Testis. Among its related pathways are Chromatin organization and Chromatin Regulation / Acetylation. Gene Ontology (GO) annotations related to this gene include chromatin binding and RNA polymerase II repressing transcription factor binding.

UniProtKB/Swiss-Prot Summary for DMAP1 Gene

  • Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases its transcriptional corepressor activity.

Gene Wiki entry for DMAP1 Gene

Additional gene information for DMAP1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DMAP1 Gene

Genomics for DMAP1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for DMAP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH01J044212 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 660.7 +0.0 27 2.3 ZNF221 SP1 HNRNPL GATAD2A TEAD4 PRDM10 ZNF629 SIX5 LEF1 IKZF1 DMAP1 lnc-ERI3-8 SZT2 HYI KDM4A-AS1 ARTN HECTD3 RPS8 ENSG00000237950 MED8
GH01J044214 Promoter 0.3 EPDnew 600.7 +1.4 1393 0.1 DMAP1 lnc-ERI3-8 SNORA110 ERI3
GH01J044774 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 53.3 +563.1 563120 4.5 RNF2 ARHGAP35 SP1 HNRNPL CREB1 GATAD2A ZNF629 REST TFE3 IKZF1 RPS8 ENSG00000225721 SNORD38A SNORD38B SNORD46 SNORD55 lnc-BEST4-3 piR-31531 TOE1 GPBP1L1
GH01J044354 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 33.8 +141.4 141446 2.2 SP1 CREB1 TEAD4 PRDM10 RFX1 SIX5 ZNF692 BACH1 FOS JUND ERI3 DMAP1 MUTYH TOE1 SZT2 lnc-KLF18-11
GH01J043705 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 31.5 -505.9 -505860 3.8 ARHGAP35 SP1 GATAD2A HNRNPL PRDM10 ZNF629 TFE3 KDM1A ZNF692 POLR2A KDM4A-AS1 ST3GAL3 DMAP1 SZT2 HYI ARTN ZNF691 P3H1 KDM4A SZT2-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around DMAP1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for DMAP1

Top Transcription factor binding sites by QIAGEN in the DMAP1 gene promoter:
  • AML1a
  • ATF
  • c-Ets-1
  • CREB
  • deltaCREB
  • N-Myc
  • Pax-5

Genomic Locations for DMAP1 Gene

Genomic Locations for DMAP1 Gene
chr1:44,213,455-44,220,681
(GRCh38/hg38)
Size:
7,227 bases
Orientation:
Plus strand
chr1:44,679,125-44,686,353
(GRCh37/hg19)
Size:
7,229 bases
Orientation:
Plus strand

Genomic View for DMAP1 Gene

Genes around DMAP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DMAP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DMAP1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for DMAP1 Gene

Proteins for DMAP1 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for DMAP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NPF5-DMAP1_HUMAN
    Recommended name:
    DNA methyltransferase 1-associated protein 1
    Protein Accession:
    Q9NPF5
    Secondary Accessions:
    • A8K001
    • D3DPY8
    • Q0JSM4
    • Q5TG41
    • Q7Z3H7
    • Q9H0S8
    • Q9P2C2

    Protein attributes for DMAP1 Gene

    Size:
    467 amino acids
    Molecular mass:
    52993 Da
    Quaternary structure:
    • Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and MEAF6. Component of a NuA4-related complex which contains EP400, TRRAP/PAF400, SRCAP, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, actin, ACTL6A/BAF53A, VPS72 and YEATS4/GAS41. DMAP1 also forms a complex with DNMT1 and HDAC2. Throughout S phase it interacts directly with the N-terminus of DNMT1, which serves to recruit DMAP1 to replication foci. DMAP1 interacts with ING1, a component of the mSin3A transcription repressor complex, although this interaction is not required for recruitment of ING1 to heterochromatin. Interacts directly with the transcriptional corepressor TSG101. Interacts with the pro-apoptotic protein DAXX. Interacts with URI1.
    SequenceCaution:
    • Sequence=BAA92663.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for DMAP1 Gene

neXtProt entry for DMAP1 Gene

Protein Expression for DMAP1 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for DMAP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for DMAP1 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Abcam antibodies for DMAP1
  • Boster Bio Antibodies for DMAP1

No data available for DME Specific Peptides for DMAP1 Gene

Domains & Families for DMAP1 Gene

Gene Families for DMAP1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for DMAP1 Gene

InterPro:
Blocks:
  • Myb DNA-binding domain
ProtoNet:

Suggested Antigen Peptide Sequences for DMAP1 Gene

GenScript: Design optimal peptide antigens:
  • DNA methyltransferase 1-associated protein 1 (DMAP1_HUMAN)
  • DNA methyltransferase 1 associated protein 1 (Q5TG37_HUMAN)
genes like me logo Genes that share domains with DMAP1: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for DMAP1 Gene

Function for DMAP1 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Molecular function for DMAP1 Gene

UniProtKB/Swiss-Prot Function:
Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases its transcriptional corepressor activity.

Phenotypes From GWAS Catalog for DMAP1 Gene

Gene Ontology (GO) - Molecular Function for DMAP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001103 RNA polymerase II repressing transcription factor binding IDA 15367675
GO:0003714 transcription corepressor activity IEA,IBA 21873635
GO:0005515 protein binding IPI 15367675
genes like me logo Genes that share ontologies with DMAP1: view
genes like me logo Genes that share phenotypes with DMAP1: view

Animal Models for DMAP1 Gene

MGI Knock Outs for DMAP1:
  • Dmap1 Dmap1<tm1.2Jrc>
  • Dmap1 Dmap1<tm1.1(KOMP)Vlcg>

Animal Model Products

CRISPR Products

miRNA for DMAP1 Gene

miRTarBase miRNAs that target DMAP1

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DMAP1

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for DMAP1 Gene

Localization for DMAP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DMAP1 Gene

Nucleus. Cytoplasm. Note=Targeted to replication foci throughout S phase by DNMT1.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DMAP1 gene
Compartment Confidence
nucleus 5
cytosol 4
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nucleoplasm (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for DMAP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000812 Swr1 complex IBA 21873635
GO:0005634 nucleus NAS 10888872
GO:0005654 nucleoplasm TAS --
GO:0005657 replication fork IEA --
GO:0005737 cytoplasm IEA,IDA 15367675
genes like me logo Genes that share ontologies with DMAP1: view

Pathways & Interactions for DMAP1 Gene

genes like me logo Genes that share pathways with DMAP1: view

Pathways by source for DMAP1 Gene

2 Cell Signaling Technology pathways for DMAP1 Gene

Gene Ontology (GO) - Biological Process for DMAP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription by RNA polymerase II IBA,IDA 15367675
GO:0006281 DNA repair IEA --
GO:0006306 DNA methylation TAS 10888872
GO:0006325 chromatin organization IEA --
GO:0006338 chromatin remodeling IEA --
genes like me logo Genes that share ontologies with DMAP1: view

No data available for SIGNOR curated interactions for DMAP1 Gene

Drugs & Compounds for DMAP1 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for DMAP1 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for DMAP1 Gene

3 REFSEQ mRNAs :
21 NCBI additional mRNA sequence :
15 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DMAP1

Alternative Splicing Database (ASD) splice patterns (SP) for DMAP1 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^
SP1: - - - - - - - - - - - - -
SP2: - - - - - - - - - - - -
SP3: - - - - - - - - -
SP4: - - - - - - - - - - -
SP5:
SP6: - - - - - - - - - - - - - -
SP7: - - - - - - - - - - -
SP8: - - - - - - - - - - - - -
SP9: - - - - - - - - - - -
SP10: - - - - - - - - - -
SP11: - - - - - - - - - - -
SP12: - - - -
SP13: - - - - - - - -
SP14: - - - - - - -
SP15: - - - - - - - - - - - - -
SP16: - - - - - - -
SP17: - -
SP18: - - - - - - - - -
SP19: - - -
SP20: - - - -
SP21:
SP22: - - - - -
SP23:

ExUns: 10a · 10b · 10c ^ 11a · 11b · 11c · 11d ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:

Relevant External Links for DMAP1 Gene

GeneLoc Exon Structure for
DMAP1

Expression for DMAP1 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for DMAP1 Gene

mRNA expression in normal human tissues for DMAP1 Gene
mRNA expression by GTEx for DMAP1 GenemRNA expression by BioGPS for DMAP1 Gene

Protein differential expression in normal tissues from HIPED for DMAP1 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (21.5) and CD8 Tcells (7.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for DMAP1 Gene



Protein tissue co-expression partners for DMAP1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DMAP1

SOURCE GeneReport for Unigene cluster for DMAP1 Gene:

Hs.8008

Evidence on tissue expression from TISSUES for DMAP1 Gene

  • Nervous system(4.9)
  • Skin(4.5)
  • Intestine(4.4)
  • Liver(4.3)
  • Kidney(2)
genes like me logo Genes that share expression patterns with DMAP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for DMAP1 Gene

Orthologs for DMAP1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for DMAP1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia DMAP1 30 31
  • 99.57 (n)
 OneToOne
Platypus
(Ornithorhynchus anatinus)
 Mammalia DMAP1 31
  • 95 (a)
 OneToOne
Cow
(Bos Taurus)
 Mammalia DMAP1 30 31
  • 92.47 (n)
 OneToMany
-- 31
  • 67 (a)
 OneToMany
Dog
(Canis familiaris)
 Mammalia DMAP1 30 31
  • 91.5 (n)
 OneToOne
Mouse
(Mus musculus)
 Mammalia Dmap1 30 17 31
  • 89.56 (n)
 OneToOne
Rat
(Rattus norvegicus)
 Mammalia Dmap1 30
  • 89.19 (n)
Oppossum
(Monodelphis domestica)
 Mammalia DMAP1 31
  • 89 (a)
 OneToOne
Chicken
(Gallus gallus)
 Aves DMAP1 30 31
  • 76.9 (n)
 OneToOne
Lizard
(Anolis carolinensis)
 Reptilia DMAP1 31
  • 86 (a)
 OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
 Amphibia dmap1 30
  • 73.81 (n)
Str.296 30
African clawed frog
(Xenopus laevis)
 Amphibia Xl.3244 30
Zebrafish
(Danio rerio)
 Actinopterygii dmap1 30 31
  • 71.78 (n)
 OneToOne
zgc55593 30
African malaria mosquito
(Anopheles gambiae)
 Insecta AgaP_AGAP007387 30
  • 56.94 (n)
Fruit Fly
(Drosophila melanogaster)
 Insecta DMAP1 30 31
  • 56.94 (n)
 OneToOne
CG11132 32
  • 48 (a)
Worm
(Caenorhabditis elegans)
 Secernentea ekl-4 30 31
  • 49.37 (n)
 OneToOne
Y105E8A.17 32
  • 40 (a)
Baker's yeast
(Saccharomyces cerevisiae)
 Saccharomycetes SWC4 31 33 33 33
  • 20 (a)
 OneToOne
Thale Cress
(Arabidopsis thaliana)
 eudicotyledons AT2G47210 30
  • 46.15 (n)
Rice
(Oryza sativa)
 Liliopsida Os05g0540800 30
  • 43.9 (n)
Sea Squirt
(Ciona savignyi)
 Ascidiacea -- 31
  • 58 (a)
 OneToOne
Sea Vase
(Ciona intestinalis)
 Ascidiacea Cin.1946 30
Species where no ortholog for DMAP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for DMAP1 Gene

ENSEMBL:
Gene Tree for DMAP1 (if available)
TreeFam:
Gene Tree for DMAP1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for DMAP1: view image

Paralogs for DMAP1 Gene

No data available for Paralogs for DMAP1 Gene

Variants for DMAP1 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for DMAP1 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
806129 Uncertain Significance: not provided 44,219,183(+) G/A MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for DMAP1 Gene

Variation tolerance for DMAP1 Gene

Residual Variation Intolerance Score: 24.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.36; 26.91% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for DMAP1 Gene

Human Gene Mutation Database (HGMD)
DMAP1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
DMAP1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for DMAP1 Gene

Disorders for DMAP1 Gene

MalaCards: The human disease database

(5) MalaCards diseases for DMAP1 Gene - From: DISEASES

- elite association - COSMIC cancer census association via MalaCards
Search DMAP1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for DMAP1

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with DMAP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for DMAP1 Gene

Publications for DMAP1 Gene

  1. DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. (PMID: 10888872) Rountree MR … Baylin SB (Nature genetics 2000) 2 3 4 23
  2. Components of a pathway maintaining histone modification and heterochromatin protein 1 binding at the pericentric heterochromatin in Mammalian cells. (PMID: 14665632) Xin H … Qin J (The Journal of biological chemistry 2004) 3 4 23
  3. Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. (PMID: 12963728) Cai Y … Conaway JW (The Journal of biological chemistry 2003) 3 4 23
  4. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 2 3 4
  5. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PMID: 16964243) Beausoleil SA … Gygi SP (Nature biotechnology 2006) 3 4

ExternalLinks

View latest publications for DMAP1 gene in Mastermind

Products for DMAP1 Gene

  • Addgene plasmids for DMAP1

Sources for DMAP1 Gene