Aliases for DLX6-AS1 Gene

Subcategory (RNA class) for DLX6-AS1 Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for DLX6-AS1 Gene

  • DLX6 Antisense RNA 1 2 3 5
  • DLX6-AS1 2 5 165
  • DLX6 Antisense RNA 1 (Non-Protein Coding) 2 3
  • Evf-2 2 3
  • DLX6 Antisense RNA (Non-Protein Coding) 3
  • Non-Protein Coding RNA 212 2
  • NONHSAG048268.2 91
  • NONHSAG048270.2 91
  • HSALNG0059740 164
  • NCRNA00212 3
  • FLJ34048 2
  • DLX6-AS 3
  • DLX6AS 3

External Ids for DLX6-AS1 Gene

Previous HGNC Symbols for DLX6-AS1 Gene

  • NCRNA00212

Previous GeneCards Identifiers for DLX6-AS1 Gene

  • GC07M096595

Summaries for DLX6-AS1 Gene

GeneCards Summary for DLX6-AS1 Gene

DLX6-AS1 (DLX6 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with DLX6-AS1 include Neuropathy and Split-Hand/Foot Malformation 2.

Rfam classification for DLX6-AS1 Gene

  • Embryonic ventral forebrain RNA 1 conserved region 1
  • Embryonic ventral forebrain-2 long ncRNA
  • Embryonic ventral forebrain RNA 1 conserved region 2

Additional gene information for DLX6-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for DLX6-AS1 Gene

Genomics for DLX6-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for DLX6-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J097004 Promoter/Enhancer 2.6 VISTA UCNEbase EPDnew Ensembl ENCODE CraniofacialAtlas 600.4 +8.3 8268 3.1 RNF2 HNRNPL GATAD2A PRDM10 ZNF629 NFKBIZ PRDM1 RBFOX2 RXRB POLR2A DLX6 lnc-DLX6-1 DLX6-AS1 ENSG00000274709 DLX5
GH07J097012 Promoter 0.8 UCNEbase EPDnew 600.7 +1.9 1917 0.3 EZH2 CBX8 DLX6-AS1 ENSG00000274709 DLX6 DLX5
GH07J097014 Promoter 0.5 EPDnew 600.7 +0.0 8 0.1 EZH2 CBX8 DLX6-AS1 ENSG00000274709 SEM1 DLX6 DLX5
GH07J097013 Enhancer 0.4 FANTOM5 600.7 +1.2 1158 0.2 POLR2A EZH2 ZSCAN29 SP1 DLX6-AS1 ENSG00000274709 DLX5 DLX6
GH07J097016 Promoter/Enhancer 1.4 FANTOM5 ENCODE CraniofacialAtlas 0.7 -2.9 -2945 1.5 HNRNPL GATAD2A CTCF PRDM10 ZNF629 TFE3 RCOR2 ZIC2 ZSCAN4 RBFOX2 HSALNG0059742 DLX6 DLX5 DLX6-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around DLX6-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for DLX6-AS1 Gene

Genomic Locations for DLX6-AS1 Gene
chr7:96,950,685-97,014,088
(GRCh38/hg38)
Size:
63,404 bases
Orientation:
Minus strand
chr7:96,584,453-96,643,377
(GRCh37/hg19)
Size:
58,925 bases
Orientation:
Minus strand

Genomic View for DLX6-AS1 Gene

Genes around DLX6-AS1 on UCSC Golden Path with GeneCards custom track
DLX6-AS1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
DLX6-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DLX6-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DLX6-AS1 Gene

Proteins for DLX6-AS1 Gene

Post-translational modifications for DLX6-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DLX6-AS1 Gene

Domains & Families for DLX6-AS1 Gene

Gene Families for DLX6-AS1 Gene

genes like me logo Genes that share domains with DLX6-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for DLX6-AS1 Gene

Function for DLX6-AS1 Gene

Phenotypes From GWAS Catalog for DLX6-AS1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DLX6-AS1 Gene

Localization for DLX6-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DLX6-AS1 gene
Compartment Confidence
nucleus 2
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for DLX6-AS1 Gene

Pathways & Interactions for DLX6-AS1 Gene

PathCards logo

SuperPathways for DLX6-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for DLX6-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for DLX6-AS1 Gene

Drugs & Compounds for DLX6-AS1 Gene

No Compound Related Data Available

Transcripts for DLX6-AS1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for DLX6-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00005AE633_9606 lncRNA 565 4

Ensembl: ENST00000437541 (view in UCSC) ,

LncBook: HSALNT0125985,

LNCipedia: DLX6-AS1:16, DLX6-AS1:33,

NONCODE: NONHSAT122135.2,

URS0000759F04_9606 lncRNA 1990 3

HGNC: 37151,

RefSeq: NR_015448,

LNCipedia: DLX6-AS1:2,

URS000060412C_9606 lncRNA 15364 2

Ensembl: ENST00000430027 (view in UCSC) ,

LNCipedia: DLX6-AS1:3,

URS00008B7006_9606 lncRNA 611 2

Ensembl: ENST00000430404 (view in UCSC) ,

LNCipedia: DLX6-AS1:17,

URS000197C5AD_9606 lncRNA 5168 1

Ensembl: ENST00000458352 (view in UCSC) ,

DLX6-AS1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for DLX6-AS1 Gene

12 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for DLX6-AS1 Gene

No ASD Table

Relevant External Links for DLX6-AS1 Gene

GeneLoc Exon Structure for
DLX6-AS1

Expression for DLX6-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for DLX6-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for DLX6-AS1 Gene

This gene is overexpressed in Brain - Anterior cingulate cortex (BA24) (x7.1), Brain - Caudate (basal ganglia) (x6.4), Brain - Putamen (basal ganglia) (x5.9), Brain - Nucleus accumbens (basal ganglia) (x5.8), and Brain - Amygdala (x4.8).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DLX6-AS1

SOURCE GeneReport for Unigene cluster for DLX6-AS1 Gene:

Hs.34969
genes like me logo Genes that share expression patterns with DLX6-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DLX6-AS1 Gene

Orthologs for DLX6-AS1 Gene

Evolution for DLX6-AS1 Gene

ENSEMBL:
Gene Tree for DLX6-AS1 (if available)
TreeFam:
Gene Tree for DLX6-AS1 (if available)

No data available for Orthologs for DLX6-AS1 Gene

Paralogs for DLX6-AS1 Gene

No data available for Paralogs for DLX6-AS1 Gene

Variants for DLX6-AS1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for DLX6-AS1 Gene

SNP ID Clinical significance and condition Chr 07 pos Variation AA Info Type
734073 Likely Benign: not provided 97,009,945(-) G/C SYNONYMOUS_VARIANT
774129 Benign: not provided 97,006,108(-) AGCCGCCGCC/A INFRAME_DELETION
785871 Benign: not provided 97,007,735(-) G/A SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for DLX6-AS1 Gene

Structural Variations from Database of Genomic Variants (DGV) for DLX6-AS1 Gene

Variant ID Type Subtype PubMed ID
esv1318286 CNV deletion 17803354
nsv1149699 CNV deletion 26484159
nsv824221 CNV gain 20364138
nsv981549 CNV duplication 23825009

Additional Variant Information for DLX6-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DLX6-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for DLX6-AS1 Gene

Disorders for DLX6-AS1 Gene

MalaCards: The human disease database

(6) MalaCards diseases for DLX6-AS1 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
neuropathy
  • peripheral neuropathy
split-hand/foot malformation 2
  • shfm2
nervous system disease
  • abnormality of the nervous system
lung cancer susceptibility 3
  • lncr3
astrocytoma
  • astrocytic tumor
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with DLX6-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for DLX6-AS1 Gene

Publications for DLX6-AS1 Gene

  1. Long noncoding RNA DLX6-AS1 promotes renal cell carcinoma progression via miR-26a/PTEN axis. (PMID: 28881158) Zeng X … Liu Z (Cell cycle (Georgetown, Tex.) 2017) 2 3
  2. The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. (PMID: 16705037) Feng J … Kohtz JD (Genes & development 2006) 2 3
  3. Long non-coding RNA DLX6-AS1 regulates neuroblastoma progression by targeting YAP1 via miR-497-5p. (PMID: 32289431) Li C … Yang C (Life sciences 2020) 3
  4. Down-regulated lncRNA DLX6-AS1 inhibits tumorigenesis through STAT3 signaling pathway by suppressing CADM1 promoter methylation in liver cancer stem cells. (PMID: 31171015) Wu DM … Lu J (Journal of experimental & clinical cancer research : CR 2019) 3
  5. Long noncoding RNA DLX6-AS1 promotes breast cancer progression via miR-505-3p/RUNX2 axis. (PMID: 31705901) Zhao P … Liu D (European journal of pharmacology 2019) 3

Products for DLX6-AS1 Gene

Sources for DLX6-AS1 Gene