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Aliases for DLG5 Gene

Aliases for DLG5 Gene

  • Discs Large MAGUK Scaffold Protein 5 2 3 5
  • Discs Large Protein P-Dlg 3 4
  • Placenta And Prostate DLG 3 4
  • PDLG 3 4
  • Discs, Large Homolog 5 (Drosophila) 2
  • Discs Large Protein LP-DLG 3
  • Discs, Large Homolog 5 3
  • Disks Large Homolog 5 3
  • Discs Large Homolog 5 2
  • Large Type Of P-DLG 3
  • KIAA0583 4
  • LP-DLG 3
  • P-DLG5 3

External Ids for DLG5 Gene

Previous GeneCards Identifiers for DLG5 Gene

  • GC10M078507
  • GC10M078760
  • GC10M079442
  • GC10M078895
  • GC10M079220
  • GC10M079550
  • GC10M073546

Summaries for DLG5 Gene

Entrez Gene Summary for DLG5 Gene

  • This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]

GeneCards Summary for DLG5 Gene

DLG5 (Discs Large MAGUK Scaffold Protein 5) is a Protein Coding gene. Diseases associated with DLG5 include Inflammatory Bowel Disease 5 and Inflammatory Bowel Disease 2. Gene Ontology (GO) annotations related to this gene include beta-catenin binding and receptor signaling complex scaffold activity. An important paralog of this gene is ENSG00000285130.

UniProtKB/Swiss-Prot for DLG5 Gene

  • Acts as a regulator of the Hippo signaling pathway (PubMed:28087714, PubMed:28169360). Negatively regulates the Hippo signaling pathway by mediating the interaction of MARK3 with STK3/4, bringing them together to promote MARK3-dependent hyperphosphorylation and inactivation of STK3 kinase activity toward LATS1 (PubMed:28087714). Positively regulates the Hippo signaling pathway by mediating the interaction of SCRIB with STK4/MST1 and LATS1 which is important for the activation of the Hippo signaling pathway. Involved in regulating cell proliferation, maintenance of epithelial polarity, epithelial-mesenchymal transition (EMT), cell migration and invasion (PubMed:28169360). Plays an important role in dendritic spine formation and synaptogenesis in cortical neurons; regulates synaptogenesis by enhancing the cell surface localization of N-cadherin. Acts as a positive regulator of hedgehog (Hh) signaling pathway. Plays a critical role in the early point of the SMO activity cycle by interacting with SMO at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation (By similarity).

Gene Wiki entry for DLG5 Gene

Additional gene information for DLG5 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DLG5 Gene

Genomics for DLG5 Gene

GeneHancer (GH) Regulatory Elements for DLG5 Gene

Promoters and enhancers for DLG5 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J077925 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 674.5 +0.0 19 3 SIN3A ZNF2 YY1 ZNF121 GLIS2 ZNF143 SP3 ZNF592 MBD2 GMEB1 DLG5 DLG5-AS1 RN7SL284P
GH10J077939 Promoter/Enhancer 1.2 EPDnew ENCODE 659.6 -13.7 -13708 2 BCOR HDGF USF1 GTF2E2 BACH1 ZMYM3 CEBPG ZIC2 ZNF644 ZNF121 DLG5 RN7SL284P ENSG00000204049 POLR3A RPS24 IMPDH1P5 LOC399783 H2AFZP5 DLG5-AS1
GH10J077835 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 63.7 +89.3 89305 4.5 HDGF PKNOX1 SMAD1 ATF1 ARNT IRF4 TCF12 POLR2B GLIS2 E2F8 DLG5 ENSG00000204049 RN7SL284P DLG5-AS1 PIR49876
GH10J077885 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 56.4 +37.6 37621 6.7 PKNOX1 ATF1 FOXA2 ZFP64 ARID4B NEUROD1 SIN3A GLI4 ZNF48 YY1 LOC101929347 DLG5 DLG5-AS1 ENSG00000228748 RN7SL284P ENSG00000204049 LOC399783 POLR3A RPS24
GH10J077842 Enhancer 1.4 Ensembl ENCODE dbSUPER 58.7 +80.1 80087 7.8 HDGF FOXA2 MLX ZFP64 ARID4B DMAP1 YY1 E2F8 ZNF143 FOS DLG5 ENSG00000204049 RN7SL284P DLG5-AS1 PIR49876
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around DLG5 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the DLG5 gene promoter:
  • Tal-1
  • E47
  • Egr-4
  • Sox9
  • Ik-1
  • Meis-1
  • Meis-1a
  • Meis-1b
  • Hlf
  • NF-AT4

Genomic Locations for DLG5 Gene

Genomic Locations for DLG5 Gene
chr10:77,790,787-77,926,590
(GRCh38/hg38)
Size:
135,804 bases
Orientation:
Minus strand
chr10:79,550,549-79,686,378
(GRCh37/hg19)
Size:
135,830 bases
Orientation:
Minus strand

Genomic View for DLG5 Gene

Genes around DLG5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DLG5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DLG5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DLG5 Gene

Proteins for DLG5 Gene

  • Protein details for DLG5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TDM6-DLG5_HUMAN
    Recommended name:
    Disks large homolog 5
    Protein Accession:
    Q8TDM6
    Secondary Accessions:
    • A6H8Y3
    • Q149N1
    • Q5T1H7
    • Q5T1H8
    • Q6DKG3
    • Q86WC0
    • Q8TDM7
    • Q9UE73
    • Q9Y4E3

    Protein attributes for DLG5 Gene

    Size:
    1919 amino acids
    Molecular mass:
    213868 Da
    Quaternary structure:
    • Interacts with MPP1 (PubMed:9738934). Interacts with CTNNB1 and with the third SH3 domain of SORBS3 to form a ternary complex (PubMed:12657639). Interacts (via coiled-coil domain) with MARK3. Interacts (via PDZ domain 3) with STK3/MST2 and STK4/MST1 (PubMed:28087714). Interacts with SCRIB (PubMed:28169360). Interacts with CTNB1, SMO and (via PDZ4 or guanylate kinase-like domain) with KIF7 (By similarity).
    SequenceCaution:
    • Sequence=AAI17696.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA25509.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for DLG5 Gene

    Alternative splice isoforms for DLG5 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DLG5 Gene

Post-translational modifications for DLG5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for DLG5 Gene

Domains & Families for DLG5 Gene

Gene Families for DLG5 Gene

Suggested Antigen Peptide Sequences for DLG5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TDM6

UniProtKB/Swiss-Prot:

DLG5_HUMAN :
  • The guanylate kinase-like domain interacts with the SH3 domain.
  • Belongs to the MAGUK family.
Domain:
  • The guanylate kinase-like domain interacts with the SH3 domain.
Family:
  • Belongs to the MAGUK family.
genes like me logo Genes that share domains with DLG5: view

Function for DLG5 Gene

Molecular function for DLG5 Gene

UniProtKB/Swiss-Prot Function:
Acts as a regulator of the Hippo signaling pathway (PubMed:28087714, PubMed:28169360). Negatively regulates the Hippo signaling pathway by mediating the interaction of MARK3 with STK3/4, bringing them together to promote MARK3-dependent hyperphosphorylation and inactivation of STK3 kinase activity toward LATS1 (PubMed:28087714). Positively regulates the Hippo signaling pathway by mediating the interaction of SCRIB with STK4/MST1 and LATS1 which is important for the activation of the Hippo signaling pathway. Involved in regulating cell proliferation, maintenance of epithelial polarity, epithelial-mesenchymal transition (EMT), cell migration and invasion (PubMed:28169360). Plays an important role in dendritic spine formation and synaptogenesis in cortical neurons; regulates synaptogenesis by enhancing the cell surface localization of N-cadherin. Acts as a positive regulator of hedgehog (Hh) signaling pathway. Plays a critical role in the early point of the SMO activity cycle by interacting with SMO at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation (By similarity).
GENATLAS Biochemistry:
Drosophila tumor suppressor gene,discs large 5,giant larvae homolog,expressed in placenta and in epithelial glands (prostate),interacting with p55 palmitoylated membrane protein and putatively involved in the maintenance of the structure of epithelial cell

Phenotypes From GWAS Catalog for DLG5 Gene

Gene Ontology (GO) - Molecular Function for DLG5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 23624079
GO:0008013 beta-catenin binding IDA 12657639
GO:0008092 cytoskeletal protein binding IDA 12657639
GO:0030159 receptor signaling complex scaffold activity NAS 12353226
genes like me logo Genes that share ontologies with DLG5: view
genes like me logo Genes that share phenotypes with DLG5: view

Animal Models for DLG5 Gene

MGI Knock Outs for DLG5:
  • Dlg5 Dlg5<tm1Vv>
  • Dlg5 Dlg5<tm1b(EUCOMM)Wtsi>

Animal Model Products

miRNA for DLG5 Gene

miRTarBase miRNAs that target DLG5

Clone Products

  • Addgene plasmids for DLG5

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for DLG5 Gene

Localization for DLG5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DLG5 Gene

Cell junction. Cell membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cytoplasm, cytoskeleton, cilium basal body. Note=Localized at sites of cell-cell contact.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DLG5 gene
Compartment Confidence
cytoskeleton 5
plasma membrane 4
nucleus 3
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cell Junctions (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for DLG5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm TAS,IEA --
GO:0005856 cytoskeleton IEA --
GO:0005886 plasma membrane TAS 9738934
GO:0005913 cell-cell adherens junction IEA --
GO:0014069 postsynaptic density ISS --
genes like me logo Genes that share ontologies with DLG5: view

Pathways & Interactions for DLG5 Gene

No Data Available

Gene Ontology (GO) - Biological Process for DLG5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001837 epithelial to mesenchymal transition IMP 28169360
GO:0007165 signal transduction TAS 9738934
GO:0008285 negative regulation of cell proliferation TAS 9738934
GO:0030011 maintenance of cell polarity IMP 28169360
GO:0030336 negative regulation of cell migration IMP 28169360
genes like me logo Genes that share ontologies with DLG5: view

No data available for Pathways by source and SIGNOR curated interactions for DLG5 Gene

Drugs & Compounds for DLG5 Gene

(2) Drugs for DLG5 Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Capecitabine Approved, Investigational Pharma RNA processing inhibitor and thymidylate synthase inhibitor, F-pyrimidines 1402
Fluorouracil Approved Pharma RNA processing inhibitor and thymidylate synthase inhibitor 1970
genes like me logo Genes that share compounds with DLG5: view

Transcripts for DLG5 Gene

Unigene Clusters for DLG5 Gene

Discs, large homolog 5 (Drosophila):
Representative Sequences:

Clone Products

  • Addgene plasmids for DLG5

Alternative Splicing Database (ASD) splice patterns (SP) for DLG5 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17a · 17b · 17c ^
SP1: - - - -
SP2: - - -
SP3: - - - - - -
SP4:
SP5:
SP6:
SP7: -
SP8:
SP9: - -
SP10: -
SP11:
SP12:
SP13:

ExUns: 18a · 18b ^ 19a · 19b · 19c ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27a · 27b · 27c ^ 28a · 28b ^ 29a · 29b ^ 30 ^ 31 ^ 32 ^ 33a · 33b ^ 34a · 34b ·
SP1: - - - - - -
SP2: - - - -
SP3: - - - - - -
SP4: - - - - - -
SP5: - - - - -
SP6: - - -
SP7:
SP8:
SP9:
SP10:
SP11: -
SP12: -
SP13:

Relevant External Links for DLG5 Gene

GeneLoc Exon Structure for
DLG5
ECgene alternative splicing isoforms for
DLG5

Expression for DLG5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DLG5 Gene

Protein differential expression in normal tissues from HIPED for DLG5 Gene

This gene is overexpressed in Cervix (32.4), Plasma (13.3), Placenta (9.0), and Fetal Brain (8.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for DLG5 Gene



NURSA nuclear receptor signaling pathways regulating expression of DLG5 Gene:

DLG5

SOURCE GeneReport for Unigene cluster for DLG5 Gene:

Hs.652690

mRNA Expression by UniProt/SwissProt for DLG5 Gene:

Q8TDM6-DLG5_HUMAN
Tissue specificity: Highly expressed in normal breast tissues and low-grade breast cancer tissues (at protein level) (PubMed:28169360). Highly expressed in the placenta and prostate. Expressed at a lower level in the thyroid, spinal cord, trachea, adrenal gland, skeletal muscle, pancreas, heart, brain, liver and kidney. A short splice product shows more limited expression, being absent from at least the brain.

Evidence on tissue expression from TISSUES for DLG5 Gene

  • Nervous system(4.8)
  • Lung(3.1)
  • Intestine(2.3)
genes like me logo Genes that share expression patterns with DLG5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for DLG5 Gene

Orthologs for DLG5 Gene

This gene was present in the common ancestor of animals.

Orthologs for DLG5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DLG5 34 33
  • 99.13 (n)
OneToOne
dog
(Canis familiaris)
Mammalia DLG5 34 33
  • 90.5 (n)
OneToOne
cow
(Bos Taurus)
Mammalia DLG5 34 33
  • 90.35 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Dlg5 16 34 33
  • 87.85 (n)
rat
(Rattus norvegicus)
Mammalia Dlg5 33
  • 87.03 (n)
oppossum
(Monodelphis domestica)
Mammalia DLG5 34
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia DLG5 34
  • 56 (a)
OneToOne
chicken
(Gallus gallus)
Aves DLG5 34 33
  • 66.95 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia DLG5 34
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia dlg5 33
  • 63.66 (n)
Str.5310 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.12821 33
zebrafish
(Danio rerio)
Actinopterygii dlg5a 34 33
  • 64.64 (n)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG6509 34 35
  • 25 (a)
OneToOne
Species where no ortholog for DLG5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for DLG5 Gene

ENSEMBL:
Gene Tree for DLG5 (if available)
TreeFam:
Gene Tree for DLG5 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for DLG5: view image

Paralogs for DLG5 Gene

(2) SIMAP similar genes for DLG5 Gene using alignment to 3 proteins:

  • DLG5_HUMAN
  • L8EAB8_HUMAN
  • R4GMQ2_HUMAN
genes like me logo Genes that share paralogs with DLG5: view

Variants for DLG5 Gene

Sequence variations from dbSNP and Humsavar for DLG5 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs386352298 uncertain-significance, not provided 77,794,909(-) T/G coding_sequence_variant, genic_downstream_transcript_variant, missense_variant
rs201354863 uncertain-significance, not specified 77,821,284(-) C/A/T coding_sequence_variant, intron_variant, missense_variant, non_coding_transcript_variant
rs1000035458 -- 77,791,204(-) T/C 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000060953 -- 77,798,723(-) C/T genic_downstream_transcript_variant, intron_variant
rs1000061729 -- 77,803,950(-) C/T genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for DLG5 Gene

Variant ID Type Subtype PubMed ID
nsv551557 CNV loss 21841781
nsv551555 CNV loss 21841781
nsv480415 CNV novel sequence insertion 20440878
nsv478446 CNV novel sequence insertion 20440878
nsv477237 CNV novel sequence insertion 20440878
nsv472395 CNV novel sequence insertion 20440878
nsv1126261 CNV deletion 24896259
esv3623883 CNV loss 21293372
esv3623882 CNV gain 21293372
esv3623881 CNV gain 21293372
esv34251 CNV gain 17911159
esv34173 CNV loss 18971310
esv34062 CNV loss 18971310
esv27942 CNV loss 19812545
esv2759769 CNV gain+loss 17122850
esv2738529 CNV deletion 23290073
dgv929n100 CNV gain 25217958
dgv1272n54 CNV gain 21841781
dgv1271n54 CNV gain 21841781

Variation tolerance for DLG5 Gene

Residual Variation Intolerance Score: 6.11% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.51; 71.86% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for DLG5 Gene

Human Gene Mutation Database (HGMD)
DLG5
SNPedia medical, phenotypic, and genealogical associations of SNPs for
DLG5

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DLG5 Gene

Disorders for DLG5 Gene

MalaCards: The human disease database

(5) MalaCards diseases for DLG5 Gene - From: HGMD, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
inflammatory bowel disease 5
  • ibd5
inflammatory bowel disease 2
  • ibd2
ileocolitis
  • iieocolitis
crohn's disease
  • ileitis
inflammatory bowel disease
  • inflammatory bowel diseases
- elite association - COSMIC cancer census association via MalaCards
Search DLG5 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for DLG5

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with DLG5: view

No data available for UniProtKB/Swiss-Prot and Genatlas for DLG5 Gene

Publications for DLG5 Gene

  1. Identification of a novel human homolog of the Drosophila dlg, P-dlg, specifically expressed in the gland tissues and interacting with p55. (PMID: 9738934) Nakamura H … Saya H (FEBS letters 1998) 2 3 4 22 58
  2. Single nucleotide polymorphisms of OCTN1, OCTN2, and DLG5 genes in Greek patients with Crohn's disease. (PMID: 16437728) Gazouli M … Anagnou NP (World journal of gastroenterology 2005) 3 22 44 58
  3. Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD. (PMID: 16344053) Vermeire S … Rutgeerts P (Gastroenterology 2005) 3 22 44 58
  4. Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway. (PMID: 28169360) Liu J … Liu P (Scientific reports 2017) 3 4 58
  5. DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2. (PMID: 28087714) Kwan J … Vasioukhin V (Genes & development 2016) 3 4 58

Products for DLG5 Gene

  • Addgene plasmids for DLG5

Sources for DLG5 Gene

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