Aliases for DLEU2L Gene

Subcategory (RNA class) for DLEU2L Gene

lncRNA

Quality Score for this RNA gene is

14

Aliases for DLEU2L Gene

  • Deleted In Lymphocytic Leukemia 2 Like 2 3 5
  • BCMS Upstream Neighbor-Like 2 3
  • NONHSAG001705 94
  • Lnc-PGM1-1 170
  • BCMSUNL 3

External Ids for DLEU2L Gene

Previous HGNC Symbols for DLEU2L Gene

  • BCMSUNL

Previous GeneCards Identifiers for DLEU2L Gene

  • GC01P063787
  • GC01P064014
  • GC01P062122

Summaries for DLEU2L Gene

GeneCards Summary for DLEU2L Gene

DLEU2L (Deleted In Lymphocytic Leukemia 2 Like) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with DLEU2L include Lymphocytic Leukemia.

Rfam classification for DLEU2L Gene

  • Deleted in lymphocytic leukemia 2 conserved region 6
  • Deleted in lymphocytic leukemia 2 conserved region 5
  • Deleted in lymphocytic leukemia 2 conserved region 4
  • Deleted in lymphocytic leukemia 2 conserved region 3
  • Deleted in lymphocytic leukemia 2 conserved region 2
  • Deleted in lymphocytic leukemia 2 conserved region 1

Additional gene information for DLEU2L Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for DLEU2L Gene

Genomics for DLEU2L Gene

GeneHancer (GH) Regulatory Elements for DLEU2L Gene

Promoters and enhancers for DLEU2L Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around DLEU2L on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the DLEU2L gene promoter:
  • AML1a
  • AREB6
  • ATF-2
  • Bach2
  • FOXJ2
  • FOXJ2 (long isoform)
  • Pax-4a
  • POU6F1 (c2)
  • PPAR-gamma1
  • PPAR-gamma2

Genomic Locations for DLEU2L Gene

Genomic Locations for DLEU2L Gene
chr1:63,547,082-63,550,636
(GRCh38/hg38)
Size:
3,555 bases
Orientation:
Plus strand
chr1:64,014,588-64,016,307
(GRCh37/hg19)
Size:
1,720 bases
Orientation:
Plus strand

Genomic View for DLEU2L Gene

Genes around DLEU2L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DLEU2L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DLEU2L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DLEU2L Gene

Proteins for DLEU2L Gene

Post-translational modifications for DLEU2L Gene

No Post-translational modifications

No data available for DME Specific Peptides for DLEU2L Gene

Domains & Families for DLEU2L Gene

Suggested Antigen Peptide Sequences for DLEU2L Gene

GenScript: Design optimal peptide antigens:
  • Deleted in lymphocytic leukemia 2-like (Q5JX12_HUMAN)

No data available for Gene Families , Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for DLEU2L Gene

Function for DLEU2L Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DLEU2L Gene

Localization for DLEU2L Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for DLEU2L Gene

Pathways & Interactions for DLEU2L Gene

PathCards logo

SuperPathways for DLEU2L Gene

No Data Available

Gene Ontology (GO) - Biological Process for DLEU2L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DLEU2L Gene

Drugs & Compounds for DLEU2L Gene

No Compound Related Data Available

Transcripts for DLEU2L Gene

mRNA/cDNA for DLEU2L Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(2) LNCipedia transcripts :
(1) NONCODE transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for DLEU2L Gene

No ASD Table

Relevant External Links for DLEU2L Gene

GeneLoc Exon Structure for
DLEU2L
ECgene alternative splicing isoforms for
DLEU2L

Expression for DLEU2L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DLEU2L Gene

mRNA differential expression in normal tissues according to GTEx for DLEU2L Gene

This gene is overexpressed in Muscle - Skeletal (x9.5).

NURSA nuclear receptor signaling pathways regulating expression of DLEU2L Gene:

DLEU2L

SOURCE GeneReport for Unigene cluster for DLEU2L Gene:

Hs.659291

Evidence on tissue expression from TISSUES for DLEU2L Gene

  • Nervous system(2.4)
genes like me logo Genes that share expression patterns with DLEU2L: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for DLEU2L Gene

Orthologs for DLEU2L Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for DLEU2L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DLEU2L 33
  • 98 (a)
OneToOne
Species where no ortholog for DLEU2L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for DLEU2L Gene

ENSEMBL:
Gene Tree for DLEU2L (if available)
TreeFam:
Gene Tree for DLEU2L (if available)

Paralogs for DLEU2L Gene

No data available for Paralogs for DLEU2L Gene

Variants for DLEU2L Gene

Sequence variations from dbSNP and Humsavar for DLEU2L Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1002439658 -- 63,550,716(+) A/G downstream_transcript_variant
rs1003709773 -- 63,549,387(+) T/C non_coding_transcript_variant
rs1004395004 -- 63,547,043(+) C/T upstream_transcript_variant
rs1004982530 -- 63,547,533(+) A/G upstream_transcript_variant
rs1007029182 -- 63,549,811(+) A/G non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for DLEU2L Gene

Variant ID Type Subtype PubMed ID
nsv1001451 CNV loss 25217958
nsv546434 CNV loss 21841781

Variation tolerance for DLEU2L Gene

Gene Damage Index Score: 0.01; 0.21% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for DLEU2L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DLEU2L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DLEU2L Gene

Disorders for DLEU2L Gene

MalaCards: The human disease database

(1) MalaCards diseases for DLEU2L Gene - From: GeneCards

Disorder Aliases PubMed IDs
lymphocytic leukemia
  • lymphoblastic leukemia
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for DLEU2L

genes like me logo Genes that share disorders with DLEU2L: view

No data available for UniProtKB/Swiss-Prot and Genatlas for DLEU2L Gene

Publications for DLEU2L Gene

  1. BCMSUN, a candidate gene for B-cell chronic lymphocytic leukemia and mantle-cell lymphoma, has an independently expressed homolog on 1p22-p31, BCMSUN-like. (PMID: 11072235) Mertens D … Lichter P (International journal of cancer 2000) 2 3 56

Products for DLEU2L Gene

Sources for DLEU2L Gene