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Aliases for DGCR5 Gene
Data sources for DGCR5 Gene:
Subcategory (RNA class) for DGCR5 Gene
lncRNA
Aliases for DGCR5 Gene
- DiGeorge Syndrome Critical Region Gene 5 (HGNC, NCBI Entrez Gene, Ensembl)
- DiGeorge Syndrome Critical Region Gene 10 (Non-Protein Coding) (HGNC, NCBI Entrez Gene)
- DiGeorge Syndrome Critical Region Gene 5 (Non-Protein Coding) (HGNC, NCBI Entrez Gene)
- DiGeorge Syndrome Critical Region Gene 9 (Non-Protein Coding) (HGNC, NCBI Entrez Gene)
- Long Intergenic Non-Protein Coding RNA 37 (HGNC, NCBI Entrez Gene)
- NCRNA00037 (HGNC, NCBI Entrez Gene)
- LINC00037 (HGNC, NCBI Entrez Gene)
- POM121L5P (HGNC, NCBI Entrez Gene)
- DGS-A (HGNC, NCBI Entrez Gene)
- DGS-B (HGNC, NCBI Entrez Gene)
- Cadherin EGF LAG Seven-Pass G-Type Receptor 1 Pseudogene (NCBI Entrez Gene)
- DiGeorge Syndrome Critical Region Gene 10 (HGNC)
- DiGeorge Syndrome Critical Region Gene 9 (HGNC)
- Non-Protein Coding RNA 37 (HGNC)
- DiGeorge Syndrome Gene A (NCBI Entrez Gene)
- DiGeorge Syndrome Gene B (NCBI Entrez Gene)
- NONHSAG033246.2 (NONCODE)
- HSALNG0133982 (LncBook)
- HSALNG0133989 (LncBook)
- HSALNG0133987 (LncBook)
- HSALNG0133981 (LncBook)
- Lnc-DGCR6-6 (LNCipedia)
- DGCR10 (NCBI Entrez Gene)
- X91348 (HGNC)
- DGCR9 (NCBI Entrez Gene)
- DGCR5 (Ensembl)
External Ids for DGCR5 Gene
- HGNC: 16757
- NCBI Entrez Gene: 26220
- Ensembl: ENSG00000237517
- OMIM®: 618040
Previous HGNC Symbols for DGCR5 Gene
- DGCR9
- DGCR10
Previous GeneCards Identifiers for DGCR5 Gene
- GC22U990094
- GC22P015899
- GC22P017332
- GC22P017347
- GC22P018958
- GC22P002579
- GC22P019258
- GC22P019274
- GC22P019272
- GC22P019451
- GC22P018971
- GC22P018973
- GC22P018983
- GC22P018995
- GC22P019253
- GC22P019556
Summaries for DGCR5 Gene
GeneCards Summary for DGCR5 Gene
DGCR5 (DiGeorge Syndrome Critical Region Gene 5) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with DGCR5 include Hyperprolinemia, Type I and Hyperprolinemia.
Additional gene information for DGCR5 Gene
- Monarch Initiative
- Search for DGCR5 at DataMed
- Search for DGCR5 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DGCR5 Gene
Genomics for DGCR5 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for DGCR5 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH22J018967 | Enhancer | 0.5 | ENCODE | 250.7 | -1.1 | -1080 | 0.2 | ZIC2 CEBPB MAX USF2 ATF4 RNF2 ZSCAN29 | DGCR5 HSALNG0133980 PRODH FAM246C | |
| GH22J018969 | Enhancer | 0.3 | CraniofacialAtlas | 250.7 | +0.8 | 785 | 0.4 | KLF1 GLIS2 | DGCR5 ENSG00000273032 PRODH DGCR6 FAM246C | |
| GH22J018966 | Enhancer | 0.2 | FANTOM5 | 250.7 | -1.9 | -1937 | 0.3 | DGCR5 HSALNG0133980 PRODH FAM246C | ||
| GH22J019477 | Promoter/Enhancer | 2.2 | EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER | 11.6 | +510.4 | 510397 | 4.2 | CHD2 ZBTB10 SP1 MXD4 FEZF1 SIX5 NR2C1 MNT IKZF1 ETS1 | UFD1 CDC45 DGCR8 TRMT2A RPL7AP70 DGCR11 LINC01311 RANBP1 ENSG00000273300 ENSG00000215493 | |
| GH22J019446 | Promoter/Enhancer | 2.2 | EPDnew Ensembl ENCODE CraniofacialAtlas | 11.6 | +478.8 | 478798 | 3.4 | MXD4 SP1 FEZF1 NR2C1 MNT IKZF1 SMAD5 MBD2 POLR2A ZBTB7B | C22orf39 ENSG00000185065 HIRA LOC105372860 DGCR8 TRMT2A UFD1 LINC01311 RPL8P5 RPL7AP70 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around DGCR5 on the GeneHancer Hub at the UCSC Golden Path
- Top Transcription factor binding sites by QIAGEN in the DGCR5 gene promoter:
-
- AML1a
- CREB
- deltaCREB
- Egr-1
- Egr-4
- HNF-4alpha1
- p53
- Pax-5
Genomic Locations for DGCR5 Gene
Latest Assembly
- chr22:18,968,903-19,031,605
- (GRCh38/hg38)
- Size:
- 62,703 bases
- Orientation:
- Plus strand
Previous Assembly
- chr22:18,958,011-19,018,755
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 60,745 bases
- Orientation:
- Plus strand
- chr22:18,958,027-19,018,755
- (GRCh37/hg19 by Ensembl)
- Size:
- 60,729 bases
- Orientation:
- Plus strand
Genomic View for DGCR5 Gene
Genes around DGCR5 on UCSC Golden Path with GeneCards custom track
DGCR5 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
- Cytogenetic band:
-
- 22q11.21 by HGNC
- 22q11.21 by Entrez Gene
- 22q11.21 by Ensembl
DGCR5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DGCR5 Gene
Proteins for DGCR5 Gene
Post-translational modifications for DGCR5 Gene
No Post-translational modifications
No data available for DME Specific Peptides for DGCR5 Gene
Domains & Families for DGCR5 Gene
Gene Families for DGCR5 Gene
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for DGCR5 Gene
Function for DGCR5 Gene
Phenotypes From GWAS Catalog for DGCR5 Gene
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for DGCR5 - Starting at $85 >
- * DGCR5 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
Inhibitory RNAs for research
- Origene shrna and RNAi products in human, mouse, rat for DGCR5
- Browse OriGene Inhibitory RNA Products For DGCR5
Clone products for research
- Applied Biological Materials (abm): Clones for DGCR5 - Starting at $45 >
- * DGCR5 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
Cell Lines for research
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DGCR5 Gene
Localization for DGCR5 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for DGCR5 Gene
Transcripts for DGCR5 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for DGCR5 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS00009BFB8D_9606 | lncRNA | 1326 | 2 |
RefSeq: NR_110533, NONCODE: NONHSAT191992.1, |
| URS0000BC43E4_9606 | lncRNA | 3323 | 1 |
RefSeq: NR_002733, |
| URS0000BC43F2_9606 | lncRNA | 3179 | 1 |
RefSeq: NR_045121, |
| URS0000759BEC_9606 | lncRNA | 2415 | 1 |
RefSeq: NR_024159, |
| URS000075DFDD_9606 | lncRNA | 927 | 1 |
RefSeq: NR_026651, |
DGCR5 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for DGCR5 Gene
- 12 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000399539 862 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for DGCR5 - Starting at $85 >
- * DGCR5 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
Inhibitory RNAs for research
- Origene shrna and RNAi products in human, mouse, rat for DGCR5
- Browse OriGene Inhibitory RNA Products For DGCR5
Clone products for research
- Applied Biological Materials (abm): Clones for DGCR5 - Starting at $45 >
- * DGCR5 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
Relevant External Links for DGCR5 Gene
- GeneLoc Exon Structure for
- DGCR5
Expression for DGCR5 Gene
mRNA differential expression in normal tissues according to GTEx for DGCR5 Gene
This gene is overexpressed in Brain - Cerebellar Hemisphere (x6.4), Brain - Cerebellum (x6.3), Brain - Cortex (x5.6), Brain - Frontal Cortex (BA9) (x4.7), and Brain - Anterior cingulate cortex (BA24) (x4.5).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DGCR5
SOURCE GeneReport for Unigene cluster for DGCR5 Gene:
Hs.646438Primer products for research
-
OriGene qPCR primer pairs for DGCR5
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DGCR5 Gene
Orthologs for DGCR5 Gene
No data available for Orthologs for DGCR5 Gene
Paralogs for DGCR5 Gene
No data available for Paralogs for DGCR5 Gene
Variants for DGCR5 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Additional Variant Information for DGCR5 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for DGCR5 Gene
Disorders for DGCR5 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hyperprolinemia, type i |
|
|
| hyperprolinemia |
|
|
| digeorge syndrome |
|
|
| velocardiofacial syndrome |
|
|
| lung cancer susceptibility 3 |
|
Search DGCR5 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for DGCR5
- Genetic Association Database
- (GAD)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for DGCR5 Gene
Publications for DGCR5 Gene
- Down-Regulation of LncRNA DGCR5 Correlates with Poor Prognosis in Hepatocellular Carcinoma. (PMID: 27898409) Huang R … Sun B (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016) 2 3 74
- Identification of a novel transcript disrupted by a balanced translocation associated with DiGeorge syndrome. (PMID: 8659529) Sutherland HF … Scambler PJ (American journal of human genetics 1996) 2 3 74
- LncRNA DGCR5 promotes lung adenocarcinoma (LUAD) progression via inhibiting hsa-mir-22-3p. (PMID: 29030962) Dong HX … Pan J (Journal of cellular physiology 2018) 2 3
- Human metabolic individuality in biomedical and pharmaceutical research. (PMID: 21886157) Suhre K … Gieger C (Nature 2011) 3 41
- Regulation of neural macroRNAs by the transcriptional repressor REST. (PMID: 19050060) Johnson R … Lipovich L (RNA (New York, N.Y.) 2009) 3 74
Products for DGCR5 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for DGCR5
- Origene Custom Protein Services for DGCR5
- Origene shrna and RNAi products in human, mouse, rat for DGCR5
- Browse OriGene Inhibitory RNA Products For DGCR5
- OriGene qPCR primer pairs for DGCR5
- Browse CRISPR knockouts for DGCR5
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For DGCR5
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- antibodies-online: Search results for available DGCR5 related products ranked by validation data
- antibodies-online: Search results for available DGCR5 related products ranked by validation data
- antibodies-online: Search results for available DGCR5 related products ranked by validation data
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for DGCR5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for DGCR5
- Search GeneCopoeia for miRNA 3'UTR Target clone products for DGCR5
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for DGCR5
Sources for DGCR5 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB