Aliases for DESI1 Gene
External Ids for DESI1 Gene
Previous HGNC Symbols for DESI1 Gene
Previous GeneCards Identifiers for DESI1 Gene
GeneCards Summary for DESI1 Gene
DESI1 (Desumoylating Isopeptidase 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include identical protein binding and peptidase activity. An important paralog of this gene is DESI2.
UniProtKB/Swiss-Prot Summary for DESI1 Gene
Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity (By similarity). Desumoylates ZBTB46 (By similarity). Collaborates with UBQLN4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (PubMed:29666234).