Aliases for DEPDC1 Gene
External Ids for DEPDC1 Gene
Previous GeneCards Identifiers for DEPDC1 Gene
GeneCards Summary for DEPDC1 Gene
DEPDC1 (DEP Domain Containing 1) is a Protein Coding gene. Diseases associated with DEPDC1 include Bladder Cancer. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is DEPDC1B.
UniProtKB/Swiss-Prot Summary for DEPDC1 Gene
May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.