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This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, ... See more...
Aliases for DENR Gene
Aliases for DENR Gene
External Ids for DENR Gene
- HGNC: 2769
- Entrez Gene: 8562
- Ensembl: ENSG00000139726
- OMIM: 604550
- UniProtKB: O43583
Previous GeneCards Identifiers for DENR Gene
- GC12U990118
- GC12M123069
- GC12P123045
- GC12P121675
- GC12P121674
- GC12P121762
- GC12P123237
- GC12P120197
Summaries for DENR Gene
-
This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008]
GeneCards Summary for DENR Gene
DENR (Density Regulated Re-Initiation And Release Factor) is a Protein Coding gene. Diseases associated with DENR include Optic Atrophy 1 and Optic Nerve Disease. Gene Ontology (GO) annotations related to this gene include translation initiation factor activity.
UniProtKB/Swiss-Prot Summary for DENR Gene
-
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
Additional gene information for DENR Gene
- HGNC(2769)
- Entrez Gene(8562)
- Ensembl(ENSG00000139726)
- OMIM(604550)
- UniProtKB(O43583)
- Open Targets Platform(ENSG00000139726)
- Search for DENR at DataMed
- Search for DENR at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DENR Gene
Genomics for DENR Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for DENR Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around DENR on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for DENR
- Top Transcription factor binding sites by QIAGEN in the DENR gene promoter:
-
- AP-1
- Bach2
- c-Fos
- c-Jun
- GATA-1
- IRF-1
- POU2F1
- POU2F1a
- RORalpha2
Genomic Locations for DENR Gene
Genomic Locations for DENR Gene
- chr12:122,752,824-122,771,064
- (GRCh38/hg38)
- Size:
- 18,241 bases
- Orientation:
- Plus strand
- chr12:123,237,321-123,255,953
- (GRCh37/hg19)
- Size:
- 18,633 bases
- Orientation:
- Plus strand
Genomic View for DENR Gene
Genes around DENR on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q24.31 by HGNC
- 12q24.31 by Entrez Gene
- 12q24.31 by Ensembl
DENR Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DENR Gene
Proteins for DENR Gene
-
Protein details for DENR Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O43583-DENR_HUMAN
- Recommended name:
- Density-regulated protein
- Protein Accession:
- O43583
- Q9H3U6
- Q9UKZ0
Protein attributes for DENR Gene
- Size:
- 198 amino acids
- Molecular mass:
- 22092 Da
- Quaternary structure:
-
- Interacts with MCTS1.
- SequenceCaution:
-
- Sequence=AAC02985.2; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
Protein Expression for DENR Gene
Post-translational modifications for DENR Gene
Other Protein References for DENR Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences DENR / Density Regulated Antibody
-
Custom Antibody ServicesOriGene Antibodies for DENR
- Novus Biologicals Antibodies for DENR
-
Abcam antibodies for DENR
- Invitrogen Antibodies for DENR (AFLGC-DENR)
-
Boster Bio Antibodies for DENR
-
Custom Antibody ServicesProSci Antibodies for DENR
-
Santa Cruz Biotechnology (SCBT) Antibodies for DENR
- Sino Biological Antibodies for DENR
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for DENR
- Origene Custom Protein Services for DENR
- ProSpec Recombinant Proteins for DENR
-
Abcam proteins for DENR
Assay Products
No data available for DME Specific Peptides for DENR Gene
Domains & Families for DENR Gene
Gene Families for DENR Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for DENR Gene
- InterPro:
- Blocks:
-
- Translation initiation factor SUI1
- ProtoNet:
Suggested Antigen Peptide Sequences for DENR Gene
- GenScript: Design optimal peptide antigens:
-
- Smooth muscle cell-associated protein 3 (DENR_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O43583- Family:
-
- Belongs to the DENR family.
Function for DENR Gene
Molecular function for DENR Gene
- UniProtKB/Swiss-Prot Function:
- May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated with increasing cell-density by HNRNPD. Up-regulated in ovarian and breast cancer cells by ERBB2 overexpression. Not induced by TGFB1.
- GENATLAS Biochemistry:
- density-regulated protein,expressed in cultured cells at high density but not at low density or during growth arrest
Phenotypes From GWAS Catalog for DENR Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
| GO:0003729 | mRNA binding | IBA | 21873635 |
| GO:0003743 | translation initiation factor activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 16169070 |
Phenotypes for DENR Gene
- MGI mutant phenotypes for DENR:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for DENR:
Animal Models for DENR Gene
- MGI Knock Outs for DENR:
-
- Denr Denr<tm1b(KOMP)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for DENR - Select products 50% OFF >
- * DENR CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for DENR
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DENR
-
Santa Cruz Biotechnology (SCBT) CRISPR for DENR
miRNA for DENR Gene
- miRTarBase miRNAs that target DENR
-
- mmu-miR-15a-5p (MIRT011925)
- hsa-miR-877-3p (MIRT036874)
- hsa-miR-106b-3p (MIRT038550)
- hsa-miR-425-5p (MIRT039320)
- hsa-miR-615-3p (MIRT039906)
- hsa-miR-15b-5p (MIRT046512)
- hsa-miR-221-3p (MIRT046970)
- hsa-miR-148a-3p (MIRT048024)
- hsa-let-7b-5p (MIRT051880)
- hsa-miR-190a-3p (MIRT112682)
- mmu-miR-3470b (MIRT594991)
- mmu-miR-3470a (MIRT600980)
- mmu-miR-878-3p (MIRT600981)
- mmu-miR-452-3p (MIRT600982)
- mmu-miR-717 (MIRT605072)
- mmu-miR-3097-3p (MIRT605073)
- mmu-miR-495-3p (MIRT605074)
- mmu-miR-1192 (MIRT605075)
- hsa-miR-3187-3p (MIRT659078)
- hsa-miR-4435 (MIRT659079)
- hsa-miR-588 (MIRT659080)
- hsa-miR-4701-5p (MIRT659081)
- hsa-miR-548s (MIRT659082)
- hsa-miR-6867-3p (MIRT659083)
- hsa-miR-6744-3p (MIRT659084)
- hsa-miR-4757-5p (MIRT659085)
- hsa-miR-4529-5p (MIRT659086)
- hsa-miR-7110-3p (MIRT659087)
- hsa-miR-6845-3p (MIRT659088)
- hsa-miR-4685-3p (MIRT659089)
- hsa-miR-4287 (MIRT659090)
- hsa-miR-7113-3p (MIRT659091)
- hsa-miR-6769b-3p (MIRT659092)
- hsa-miR-4469 (MIRT659093)
- hsa-miR-4723-3p (MIRT659094)
- hsa-miR-3183 (MIRT659095)
- hsa-miR-6832-3p (MIRT659096)
- hsa-miR-6768-3p (MIRT659097)
- hsa-miR-211-5p (MIRT659098)
- hsa-miR-204-5p (MIRT659099)
- hsa-miR-6125 (MIRT695769)
- hsa-miR-665 (MIRT695770)
- hsa-miR-6778-5p (MIRT695771)
- hsa-miR-1233-5p (MIRT695772)
- hsa-miR-6894-5p (MIRT695773)
- hsa-miR-6134 (MIRT695774)
- hsa-miR-7854-3p (MIRT695775)
- hsa-miR-6884-5p (MIRT695776)
- hsa-miR-485-5p (MIRT695777)
- hsa-miR-3679-5p (MIRT695778)
- hsa-miR-1185-5p (MIRT695779)
- hsa-miR-7162-3p (MIRT695780)
- hsa-miR-4453 (MIRT695781)
- hsa-miR-4538 (MIRT695782)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DENR
- Browse OriGene Inhibitory RNA Products For DENR
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DENR
Clone Products
- Applied Biological Materials (abm): Clones for DENR - Select products 50% OFF >
- * DENR as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for DENR
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DENR
Cell Line Products
-
Horizon Cell Lines for DENR
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for DENR Gene
Localization for DENR Gene
| Compartment | Confidence |
|---|---|
| cytosol | 4 |
| mitochondrion | 3 |
| plasma membrane | 2 |
| extracellular | 2 |
| cytoskeleton | 2 |
| nucleus | 2 |
| endoplasmic reticulum | 2 |
| lysosome | 2 |
| peroxisome | 1 |
| endosome | 1 |
| golgi apparatus | 1 |
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005575 | cellular_component | ND | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for DENR Gene
Pathways & Interactions for DENR Gene
Interacting Proteins for DENR Gene
Selected Interacting proteins:
ENSP00000280557
O43583-DENR_HUMAN
for DENR Gene via
STRING
MINT
UniProtKB
IID
GPS-Prot Interaction Network for DENR
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001731 | formation of translation preinitiation complex | IBA,IDA | 20713520 |
| GO:0002188 | translation reinitiation | IBA | 21873635 |
| GO:0006412 | translation | IEA | -- |
| GO:0006413 | translational initiation | IEA | -- |
| GO:0032790 | ribosome disassembly | IDA | 20713520 |
No data available for Pathways by source and SIGNOR curated interactions for DENR Gene
Transcripts for DENR Gene
mRNA/cDNA for DENR Gene
- 1 REFSEQ mRNAs :
- 13 NCBI additional mRNA sequence :
- 4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000280557 2719 nts (view in UCSC)
- ENST00000455982 1052 nts (view in UCSC)
- ENST00000539463 671 nts (view in UCSC)
- ENST00000537955 699 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for DENR - Select products 50% OFF >
- * DENR CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for DENR
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DENR
-
Santa Cruz Biotechnology (SCBT) CRISPR for DENR
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DENR
- Browse OriGene Inhibitory RNA Products For DENR
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DENR
Clone Products
- Applied Biological Materials (abm): Clones for DENR - Select products 50% OFF >
- * DENR as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for DENR
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DENR
Relevant External Links for DENR Gene
- GeneLoc Exon Structure for
- DENR
Expression for DENR Gene
This gene is overexpressed in Lavage (6.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for DENR Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DENR
SOURCE GeneReport for Unigene cluster for DENR Gene:
Hs.22393mRNA Expression by UniProt/SwissProt for DENR Gene:
O43583-DENR_HUMAN
Tissue specificity:
Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney.
Evidence on tissue expression from TISSUES for DENR Gene
- Heart(4.6)
- Liver(4.5)
- Nervous system(3.9)
- Muscle(3)
- Kidney(2.8)
- Skin(2.7)
- Lung(2.4)
- Blood(2.3)
- Spleen(2.3)
- Intestine(2.2)
- Stomach(2.1)
Primer Products
-
OriGene qPCR primer pairs for DENR
-
OriGene qPCR primer pairs and template standards for DENR
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for DENR Gene
Orthologs for DENR Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | DENR 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | -- 31 |
|
OneToMany | |
| DENR 30 31 |
|
OneToMany | |||
| Dog (Canis familiaris) |
Mammalia | DENR 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Rat (Rattus norvegicus) |
Mammalia | LOC687565 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | DENR 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Denr 30 17 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | DENR 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | DENR 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | denr 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | denr 30 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG9099 30 31 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP006125 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | Y47D3A.21 30 31 |
|
OneToOne | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | TMA22 30 31 33 |
|
OneToOne | |
| K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0F21934g 30 |
|
||
| A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_ACL112C 30 |
|
||
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT5G11900 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os01g0195500 30 |
|
||
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | SPBC16C6.05 30 |
|
||
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU02984 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.7885 31 |
|
OneToOne |
- Species where no ortholog for DENR was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for DENR Gene
- ENSEMBL:
- Gene Tree for DENR (if available)
- TreeFam:
- Gene Tree for DENR (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for DENR: view image
Paralogs for DENR Gene
Pseudogenes.org Pseudogenes for DENR Gene
No data available for Paralogs for DENR Gene
Variants for DENR Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for DENR Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 797357 | Likely Benign: not provided | 122,762,178(+) | C/T | INTRON_VARIANT |
Residual Variation Intolerance Score:
69.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.18;
4.08% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for DENR Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DENR Gene
Disorders for DENR Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| optic atrophy 1 |
|
|
| optic nerve disease |
|
|
| cranial nerve disease |
|
|
| 3-methylglutaconic aciduria, type iii |
|
|
| parkinson disease, late-onset |
|
|
Search DENR in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for DENR
No data available for UniProtKB/Swiss-Prot and Genatlas for DENR Gene
Publications for DENR Gene
- drp, a novel protein expressed at high cell density but not during growth arrest. (PMID: 9628587) Deyo JE … Tainsky MA (DNA and cell biology 1998) 2 3 4 23
- Activities of Ligatin and MCT-1/DENR in eukaryotic translation initiation and ribosomal recycling. (PMID: 20713520) Skabkin MA … Pestova TV (Genes & development 2010) 2 3 4
- MCT-1 protein interacts with the cap complex and modulates messenger RNA translational profiles. (PMID: 16982740) Reinert LS … Gartenhaus RB (Cancer research 2006) 2 3 4
- De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation. (PMID: 27239039) Haas MA … Heng JI (Cell reports 2016) 2 3
- Post-transcriptional control of the MCT-1-associated protein DENR/DRP by RNA-binding protein AUF1. (PMID: 17878526) Mazan-Mamczarz K … Gartenhaus RB (Cancer genomics & proteomics 2007) 3 4
ExternalLinks
Products for DENR Gene
- Custom Antibody ServicesOriGene Antibodies for DENR
- Browse OriGene ELISA Kits
- Custom Assay Services
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- OriGene qPCR primer pairs for DENR
- OriGene qPCR primer pairs and template standards for DENR
- OriGene CRISPR knockouts for DENR
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- Sino Biological Human cDNA Clone for DENR
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for DENR
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for DENR
- Novus Biologicals proteins and lysates for DENR
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for DENR
- Abcam proteins for DENR
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for DENR (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for DENR (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for DENR (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for DENR CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for DENR
- antibodies-online: Show 9 available Density Regulated Protein Antibodies ranked by validation data
- Compare Top Density Regulated Protein Antibodies
- antibodies-online: Show 6 available Density Regulated Protein Elisa Kits ranked by validation data
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- antibodies-online: Show 14 available Density Regulated Protein Proteins ranked by validation data
- Compare Top Density Regulated Protein Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for DENR
- Search Santa Cruz Biotechnology (SCBT) for DENR siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for DENR
- Custom Antibody ServicesProSci Antibodies for DENR
- Search for DENR Proteins at ProSci
- Horizon Cell Lines for DENR
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DENR
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- Boster Bio Antibodies for DENR
- Browse Boster Bio ELISA Kits
Sources for DENR Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
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