Aliases for DENND2A Gene
External Ids for DENND2A Gene
Previous HGNC Symbols for DENND2A Gene
Previous GeneCards Identifiers for DENND2A Gene
GeneCards Summary for DENND2A Gene
DENND2A (DENN Domain Containing 2A) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and RAB GEFs exchange GTP for GDP on RABs. Gene Ontology (GO) annotations related to this gene include Rab guanyl-nucleotide exchange factor activity. An important paralog of this gene is DENND2B.
UniProtKB/Swiss-Prot Summary for DENND2A Gene
Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May play a role in late endosomes back to trans-Golgi network/TGN transport.