Aliases for DEFB127 Gene
External Ids for DEFB127 Gene
Previous HGNC Symbols for DEFB127 Gene
Previous GeneCards Identifiers for DEFB127 Gene
Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13. [provided by RefSeq, Nov 2014]
GeneCards Summary for DEFB127 Gene
DEFB127 (Defensin Beta 127) is a Protein Coding gene. Diseases associated with DEFB127 include Testicular Infarct and Dermatitis, Atopic, 2. Among its related pathways are Defensins and Innate Immune System. An important paralog of this gene is DEFB128.
UniProtKB/Swiss-Prot Summary for DEFB127 Gene
Has antibacterial activity.