Aliases for DEFB123 Gene
External Ids for DEFB123 Gene
Previous GeneCards Identifiers for DEFB123 Gene
Defensins are cysteine-rich cationic polypeptides that are important in the host immunologic response to invading microorganisms. This antimicrobial protein is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20q11.1. Two transcript variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq, Nov 2014]
GeneCards Summary for DEFB123 Gene
DEFB123 (Defensin Beta 123) is a Protein Coding gene. Diseases associated with DEFB123 include Intracranial Hypotension. Among its related pathways are Defensins and Innate Immune System. An important paralog of this gene is DEFB121.
UniProtKB/Swiss-Prot Summary for DEFB123 Gene
Has antibacterial activity.