Aliases for DEFB118 Gene
External Ids for DEFB118 Gene
Previous HGNC Symbols for DEFB118 Gene
Previous GeneCards Identifiers for DEFB118 Gene
This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity against E. coli. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. [provided by RefSeq, Nov 2014]
GeneCards Summary for DEFB118 Gene
DEFB118 (Defensin Beta 118) is a Protein Coding gene. Diseases associated with DEFB118 include Vulvitis. Among its related pathways are Defensins and Innate Immune System. An important paralog of this gene is DEFB132.
UniProtKB/Swiss-Prot Summary for DEFB118 Gene
Has antibacterial activity.