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Aliases for DEFB117 Gene

Aliases for DEFB117 Gene

  • Defensin Beta 117 (Pseudogene) 2 3 5
  • Defensin, Beta 117 2 3
  • Defensin, Beta 17 2 3
  • Defensin, Beta 117 (Pseudogene) 2
  • DEFB-17 3

External Ids for DEFB117 Gene

Previous GeneCards Identifiers for DEFB117 Gene

  • GC20U990233
  • GC20P029412
  • GC20P029948
  • GC20P029939

Summaries for DEFB117 Gene

GeneCards Summary for DEFB117 Gene

DEFB117 (Defensin Beta 117 (Pseudogene)) is a Pseudogene.

Additional gene information for DEFB117 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DEFB117 Gene

Genomics for DEFB117 Gene

GeneHancer (GH) Regulatory Elements for DEFB117 Gene

Promoters and enhancers for DEFB117 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20J031368 Promoter 0.5 EPDnew 0.4 +7.8 7809 0.1 DEFB118 DEFB117
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around DEFB117 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the DEFB117 gene promoter:
  • Max
  • c-Myc
  • FOXF2
  • TBP
  • POU2F1
  • POU2F1a
  • AML1a
  • STAT5A
  • SRY

Genomic Locations for DEFB117 Gene

Genomic Locations for DEFB117 Gene
156 bases
Plus strand
156 bases
Plus strand

Genomic View for DEFB117 Gene

Genes around DEFB117 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DEFB117 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DEFB117 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DEFB117 Gene

Proteins for DEFB117 Gene

  • Protein details for DEFB117 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein Accession:

    Protein attributes for DEFB117 Gene

    42 amino acids
    Molecular mass:
    4745 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DEFB117 Gene

Post-translational modifications for DEFB117 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DEFB117 Gene

Domains & Families for DEFB117 Gene

Gene Families for DEFB117 Gene

  • Belongs to the beta-defensin family.

Protein Domains for DEFB117 Gene


Suggested Antigen Peptide Sequences for DEFB117 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DEFB117: view

No data available for UniProtKB/Swiss-Prot for DEFB117 Gene

Function for DEFB117 Gene

Molecular function for DEFB117 Gene

UniProtKB/TrEMBL Function:
Has antibacterial activity.
  • Q30KQ3

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DEFB117 Gene

Localization for DEFB117 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DEFB117 gene
Compartment Confidence
extracellular 3
cytosol 2
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for DEFB117 Gene

Pathways & Interactions for DEFB117 Gene

SuperPathways for DEFB117 Gene

No Data Available

Interacting Proteins for DEFB117 Gene

Gene Ontology (GO) - Biological Process for DEFB117 Gene


No data available for Pathways by source and SIGNOR curated interactions for DEFB117 Gene

Drugs & Compounds for DEFB117 Gene

No Compound Related Data Available

Transcripts for DEFB117 Gene

mRNA/cDNA for DEFB117 Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DEFB117 Gene

Defensin, beta 117:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DEFB117 Gene

No ASD Table

Relevant External Links for DEFB117 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DEFB117 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DEFB117 Gene

NURSA nuclear receptor signaling pathways regulating expression of DEFB117 Gene:


SOURCE GeneReport for Unigene cluster for DEFB117 Gene:

genes like me logo Genes that share expression patterns with DEFB117: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DEFB117 Gene

Orthologs for DEFB117 Gene

Evolution for DEFB117 Gene

Gene Tree for DEFB117 (if available)
Gene Tree for DEFB117 (if available)

No data available for Orthologs for DEFB117 Gene

Paralogs for DEFB117 Gene

(3) SIMAP similar genes for DEFB117 Gene using alignment to 1 proteins:

  • Q30KQ3_HUMAN
genes like me logo Genes that share paralogs with DEFB117: view

No data available for Paralogs for DEFB117 Gene

Variants for DEFB117 Gene

Additional Variant Information for DEFB117 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for DEFB117 Gene

Disorders for DEFB117 Gene

Additional Disease Information for DEFB117

No disorders were found for DEFB117 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DEFB117 Gene

Publications for DEFB117 Gene

  1. Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract. (PMID: 16033865) Patil AA … Zhang G (Physiological genomics 2005) 2 3 58
  2. Discovery of five conserved beta -defensin gene clusters using a computational search strategy. (PMID: 11854508) Schutte BC … McCray PB (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58

Products for DEFB117 Gene

Sources for DEFB117 Gene

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