Aliases for DEFB108A Gene

Aliases for DEFB108A Gene

  • Defensin Beta 108A 2 3 5
  • Defensin Beta 108 Pseudogene 1 2 3
  • DEFB108P1 3 4
  • DEFB-8 2 3
  • Putative Beta-Defensin 108B Pseudogene 1/2 4
  • Defensin, Beta 108, Pseudogene 1 2
  • Putative Beta-Defensin 108A 4
  • Defensin, Beta 108B 3
  • Defensin, Beta 108A 4
  • Defensin, Beta 108C 4
  • Defensin, Beta 108 2
  • Beta-Defensin 108B 3
  • Beta-Defensin 8 3
  • DEFB108P2 4
  • DEFB108B 3
  • DEFB108A 5
  • DEFB108 3
  • DEFB8 3
  • HBD-8 3
  • BD-8 3

External Ids for DEFB108A Gene

Previous HGNC Symbols for DEFB108A Gene

  • DEFB108
  • DEFB108P1

Summaries for DEFB108A Gene

GeneCards Summary for DEFB108A Gene

DEFB108A (Defensin Beta 108A) is a Pseudogene. Among its related pathways are Defensins and Innate Immune System.

UniProtKB/Swiss-Prot Summary for DEFB108A Gene

Additional gene information for DEFB108A Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DEFB108A Gene

Genomics for DEFB108A Gene

Genomic Locations for DEFB108A Gene

Genomic Locations for DEFB108A Gene
chr8:7,934,264-7,938,770
(GRCh38/hg38)
Size:
4,507 bases
Orientation:
Minus strand
chr8:7,791,934-7,796,292
(GRCh37/hg19)
Size:
4,359 bases
Orientation:
Minus strand

Genomic View for DEFB108A Gene

Genes around DEFB108A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DEFB108A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DEFB108A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DEFB108A Gene

No data available for GeneHancer (GH) Regulatory Elements for DEFB108A Gene

Proteins for DEFB108A Gene

  • Protein details for DEFB108A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MXU0-DB108_HUMAN
    Recommended name:
    Putative beta-defensin 108A
    Protein Accession:
    A8MXU0

    Protein attributes for DEFB108A Gene

    Size:
    73 amino acids
    Molecular mass:
    8390 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DEFB108A Gene

Post-translational modifications for DEFB108A Gene

No Post-translational modifications

No data available for DME Specific Peptides for DEFB108A Gene

Domains & Families for DEFB108A Gene

Gene Families for DEFB108A Gene

Protein Domains for DEFB108A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for DEFB108A Gene

GenScript: Design optimal peptide antigens:
  • Putative beta-defensin 108B pseudogene 1 (D108A_HUMAN)

Graphical View of Domain Structure for InterPro Entry

A8MXU0

UniProtKB/Swiss-Prot:

DB108_HUMAN :
  • Belongs to the beta-defensin family.
Family:
  • Belongs to the beta-defensin family.
genes like me logo Genes that share domains with DEFB108A: view

Function for DEFB108A Gene

Molecular function for DEFB108A Gene

UniProtKB/Swiss-Prot Function:
Has antibacterial activity.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DEFB108A Gene

Localization for DEFB108A Gene

Subcellular locations from UniProtKB/Swiss-Prot for DEFB108A Gene

Secreted.

Gene Ontology (GO) - Cellular Components for DEFB108A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with DEFB108A: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for DEFB108A Gene

Pathways & Interactions for DEFB108A Gene

PathCards logo

SuperPathways for DEFB108A Gene

genes like me logo Genes that share pathways with DEFB108A: view

Pathways by source for DEFB108A Gene

Gene Ontology (GO) - Biological Process for DEFB108A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042742 defense response to bacterium IEA --
GO:0045087 innate immune response IEA --
genes like me logo Genes that share ontologies with DEFB108A: view

No data available for Interacting Proteins and SIGNOR curated interactions for DEFB108A Gene

Drugs & Compounds for DEFB108A Gene

No Compound Related Data Available

Transcripts for DEFB108A Gene

mRNA/cDNA for DEFB108A Gene

1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for DEFB108A Gene

No ASD Table

Relevant External Links for DEFB108A Gene

GeneLoc Exon Structure for
DEFB108A

Expression for DEFB108A Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DEFB108A Gene

Orthologs for DEFB108A Gene

Evolution for DEFB108A Gene

ENSEMBL:
Gene Tree for DEFB108A (if available)
TreeFam:
Gene Tree for DEFB108A (if available)

No data available for Orthologs for DEFB108A Gene

Paralogs for DEFB108A Gene

No data available for Paralogs for DEFB108A Gene

Variants for DEFB108A Gene

Additional Variant Information for DEFB108A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DEFB108A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for DEFB108A Gene

Disorders for DEFB108A Gene

Additional Disease Information for DEFB108A

No disorders were found for DEFB108A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DEFB108A Gene

Publications for DEFB108A Gene

  1. Duplication and selection in the evolution of primate beta-defensin genes. (PMID: 12734011) Semple CA … Dorin JR (Genome biology 2003) 3 4
  2. Discovery of five conserved beta -defensin gene clusters using a computational search strategy. (PMID: 11854508) Schutte BC … McCray PB (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
  3. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 4

Products for DEFB108A Gene

Sources for DEFB108A Gene