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Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of t... See more...
Aliases for DEFB106B Gene
Aliases for DEFB106B Gene
External Ids for DEFB106B Gene
- HGNC: 28879
- NCBI Entrez Gene: 503841
- Ensembl: ENSG00000187082
- UniProtKB/Swiss-Prot: Q8N104
Previous GeneCards Identifiers for DEFB106B Gene
- GC08U900536
- GC08M007329
- GC08M007340
Summaries for DEFB106B Gene
-
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106B, represents the more telomeric copy. [provided by RefSeq, Oct 2014]
GeneCards Summary for DEFB106B Gene
DEFB106B (Defensin Beta 106B) is a Protein Coding gene. Among its related pathways are Defensins and Innate Immune System. An important paralog of this gene is DEFB106A.
UniProtKB/Swiss-Prot Summary for DEFB106B Gene
-
Has antibacterial activity (PubMed:12600824). Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:23938203).
Additional gene information for DEFB106B Gene
- Alliance of Genome Resources
- Search for DEFB106B at DataMed
- Search for DEFB106B at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DEFB106B Gene
Genomics for DEFB106B Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for DEFB106B Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH08J007487 | Promoter | 0.3 | EPDnew | 250.7 | -1.3 | -1260 | 0.1 | DEFB105B DEFB106B HSALNG0063207-001 HSALNG0063208 | ||
| GH08J007481 | Promoter | 0.3 | EPDnew | 0.4 | +5.1 | 5076 | 0.1 | lnc-DEFB104B-1 DEFB104B DEFB106B HSALNG0063207-001 | ||
| GH08J007478 | Enhancer | 0.2 | Ensembl | 0.4 | +8.0 | 7999 | 0.4 | lnc-DEFB104B-1 DEFB104B DEFB106B HSALNG0063205 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around DEFB106B on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for DEFB106B
- Top Transcription factor binding sites by QIAGEN in the DEFB106B gene promoter:
-
- AREB6
- Cart-1
- Chx10
- CUTL1
- HSF1 (long)
- HSF1short
- Pbx1a
- POU2F1
- POU2F1a
- S8
Genomic Locations for DEFB106B Gene
Latest Assembly
- chr8:7,482,504-7,486,400
- (GRCh38/hg38)
- Size:
- 3,897 bases
- Orientation:
- Minus strand
Previous Assembly
- chr8:7,340,026-7,343,922
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 3,897 bases
- Orientation:
- Minus strand
Alternative Locations (GRCh38/hg38)
- chr8(ALT_REF_LOCI_1):165,611-169,505 (-)
- chr8(PATCHES):5,422,413-5,426,347 (+)
Genomic View for DEFB106B Gene
Genes around DEFB106B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p23.1 by HGNC
- 8p23.1 by Entrez Gene
- 8p23.1 by Ensembl
DEFB106B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DEFB106B Gene
Proteins for DEFB106B Gene
-
Protein details for DEFB106B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N104-D106A_HUMAN
- Recommended name:
- Beta-defensin 106
- Protein Accession:
- Q8N104
- Q2NKR0
- Q496I8
Protein attributes for DEFB106B Gene
- Size:
- 65 amino acids
- Molecular mass:
- 7369 Da
- Quaternary structure:
-
- Monomer (PubMed:23938203). Interacts with CCR2 (via extracellular N-terminal region); this interaction may preferentially require specific tyrosine sulfation on CCR2 (PubMed:23938203).
Post-translational modifications for DEFB106B Gene
No Post-translational modifications
Other Protein References for DEFB106B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- Novus Biologicals Antibodies for DEFB106B
- antibodies-online: Show 6 available DEFB106B Antibodies ranked by validation data
- Compare Top DEFB106B Antibodies
-
Quality Products:
Protein products for research
-
OriGene Purified Proteins for DEFB106B
- Search Origene for MassSpec and Protein Over-expression Lysates for DEFB106B
- Origene Custom Protein Services for DEFB106B
- Novus Biologicals proteins for DEFB106B
Assay products for research
No data available for DME Specific Peptides for DEFB106B Gene
Domains & Families for DEFB106B Gene
Gene Families for DEFB106B Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted secreted proteins
Protein Domains for DEFB106B Gene
- InterPro:
Suggested Antigen Peptide Sequences for DEFB106B Gene
- GenScript: Design optimal peptide antigens:
-
- Defensin, beta 106 (D106A_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8N104- Family:
-
- Belongs to the beta-defensin family.
Function for DEFB106B Gene
Molecular function for DEFB106B Gene
- UniProtKB/Swiss-Prot Function:
- Has antibacterial activity (PubMed:12600824). Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:23938203).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001530 | lipopolysaccharide binding | IDA | 24189797 |
| GO:0005515 | protein binding | IPI | 23938203 |
| GO:0008201 | heparin binding | IDA | 24189797 |
| GO:0031727 | CCR2 chemokine receptor binding | IDA | 23938203 |
Phenotypes for DEFB106B Gene
- GenomeRNAi human phenotypes for DEFB106B:
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for DEFB106B - Starting at $85 >
- * DEFB106B CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for DEFB106B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DEFB106B
-
Santa Cruz Biotechnology (SCBT) CRISPR for DEFB106B
miRNA for DEFB106B Gene
- miRTarBase miRNAs that target DEFB106B
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DEFB106B
- Browse OriGene Inhibitory RNA Products For DEFB106B
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Clone products for research
- Applied Biological Materials (abm): Clones for DEFB106B - Starting at $45 >
- * DEFB106B as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
-
OriGene ORF clones in human for DEFB106B
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for DEFB106B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DEFB106B
Cell Lines for research
-
Horizon Cell Lines for DEFB106B
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for DEFB106B Gene
Localization for DEFB106B Gene
Subcellular locations from UniProtKB/Swiss-Prot for DEFB106B Gene
- Secreted. Membrane. Note=Associates with tumor cell membrane-derived microvesicles (PubMed:23938203). {ECO:0000269 PubMed:23938203}.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0005634 | nucleus | IDA | 24189797 |
| GO:0016020 | membrane | IEA | -- |
| GO:0019898 | extrinsic component of membrane | IDA | 23938203 |
| GO:1990742 | microvesicle | IDA | 23938203 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for DEFB106B Gene
Pathways & Interactions for DEFB106B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Defensins |
.81
.81
|
|
| 2 | Innate Immune System |
.61
|
|
Pathways by source for DEFB106B Gene
5 Reactome pathways for DEFB106B Gene
Interacting Proteins for DEFB106B Gene
GPS-Prot Interaction Network for DEFB106B
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006952 | defense response | IEA | -- |
| GO:0042742 | defense response to bacterium | IEA | -- |
| GO:0045087 | innate immune response | IDA | 24189797 |
| GO:0050829 | defense response to Gram-negative bacterium | IDA | 24189797 |
| GO:0050830 | defense response to Gram-positive bacterium | IDA | 24189797 |
No data available for SIGNOR curated interactions for DEFB106B Gene
Transcripts for DEFB106B Gene
mRNA/cDNA for DEFB106B Gene
- 1 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000335479 316 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for DEFB106B - Starting at $85 >
- * DEFB106B CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for DEFB106B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DEFB106B
-
Santa Cruz Biotechnology (SCBT) CRISPR for DEFB106B
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DEFB106B
- Browse OriGene Inhibitory RNA Products For DEFB106B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DEFB106B
Clone products for research
- Applied Biological Materials (abm): Clones for DEFB106B - Starting at $45 >
- * DEFB106B as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
-
OriGene ORF clones in human for DEFB106B
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for DEFB106B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DEFB106B
Relevant External Links for DEFB106B Gene
- GeneLoc Exon Structure for
- DEFB106B
Expression for DEFB106B Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DEFB106B
SOURCE GeneReport for Unigene cluster for DEFB106B Gene:
Hs.511958mRNA Expression by UniProt/SwissProt for DEFB106B Gene:
Q8N104-D106A_HUMAN
Tissue specificity:
Expressed specifically in epididymis and lung.
Evidence on tissue expression from TISSUES for DEFB106B Gene
- Lung(4.2)
Primer products for research
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for DEFB106B Gene
Orthologs for DEFB106B Gene
This gene was present in the common ancestor of human and mouse.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | DEFB106A 30 |
|
OneToMany | |
| Mouse (Mus musculus) |
Mammalia | Defb34 30 |
|
ManyToMany |
- Species where no ortholog for DEFB106B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Cow (Bos Taurus)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for DEFB106B Gene
- ENSEMBL:
- Gene Tree for DEFB106B (if available)
- TreeFam:
- Gene Tree for DEFB106B (if available)
- Alliance of Genome Resources:
- Additional Orthologs for DEFB106B
Paralogs for DEFB106B Gene
Variants for DEFB106B Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
64.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.00;
0.03% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for DEFB106B Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for DEFB106B Gene
Disorders for DEFB106B Gene
Additional Disease Information for DEFB106B
No disorders were found for DEFB106B Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DEFB106B Gene
Publications for DEFB106B Gene
- Structural basis for the interaction of human β-defensin 6 and its putative chemokine receptor CCR2 and breast cancer microvesicles. (PMID: 23938203) De Paula VS … Valente AP (Journal of molecular biology 2013) 3 4
- Duplication and selection in the evolution of primate beta-defensin genes. (PMID: 12734011) Semple CA … Dorin JR (Genome biology 2003) 3 4
- Discovery of five conserved beta -defensin gene clusters using a computational search strategy. (PMID: 11854508) Schutte BC … McCray PB (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 4
- Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice. (PMID: 12193721) Yamaguchi Y … Ouchi Y (Journal of immunology (Baltimore, Md. : 1950) 2002) 3 4
- Soluble fusion expression, characterization and localization of human β-defensin 6. (PMID: 24189797) Xin A … Zhang Y (Molecular medicine reports 2014) 3
ExternalLinks
Products for DEFB106B Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for DEFB106B
- Search Origene for MassSpec and Protein Over-expression Lysates for DEFB106B
- Origene Custom Protein Services for DEFB106B
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DEFB106B
- Browse OriGene Inhibitory RNA Products For DEFB106B
- Browse OriGene qPCR primer pairs and template standards
- OriGene CRISPR knockouts for DEFB106B
- OriGene ORF clones in human for DEFB106B
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For DEFB106B
- Sino Biological Human cDNA Clone for DEFB106B
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for DEFB106B
- Novus Biologicals proteins for DEFB106B
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- VectorBuilder Custom and pre-made DNA vectors for DEFB106B (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for DEFB106B (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Virus packaging for DEFB106B CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for DEFB106B
- antibodies-online: Show 6 available DEFB106B Antibodies ranked by validation data
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- Quality Products:
- antibodies-online: Search results for available DEFB106B related products ranked by validation data
- antibodies-online: Search results for available DEFB106B related products ranked by validation data
- Horizon Cell Lines for DEFB106B
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DEFB106B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DEFB106B
- Search GeneCopoeia for miRNA 3'UTR Target clone products for DEFB106B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DEFB106B
Sources for DEFB106B Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources