Aliases for DEFB103B Gene
External Ids for DEFB103B Gene
Previous GeneCards Identifiers for DEFB103B Gene
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense. [provided by RefSeq, Oct 2014]
GeneCards Summary for DEFB103B Gene
DEFB103B (Defensin Beta 103B) is a Protein Coding gene. Diseases associated with DEFB103B include Anal Fistula and Oral Candidiasis. Among its related pathways are Defensins and Innate Immune System. An important paralog of this gene is DEFB103A.
UniProtKB/Swiss-Prot Summary for DEFB103B Gene
Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.