Aliases for DDX23 Gene
Aliases for DDX23 Gene
External Ids for DDX23 Gene
- HGNC: 17347
- Entrez Gene: 9416
- Ensembl: ENSG00000174243
- OMIM: 612172
- UniProtKB: Q9BUQ8
Previous GeneCards Identifiers for DDX23 Gene
- GC12M048940
- GC12M047509
- GC12M049223
- GC12M046256
Summaries for DDX23 Gene
-
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for DDX23 Gene
DDX23 (DEAD-Box Helicase 23) is a Protein Coding gene. Diseases associated with DDX23 include Distal Hereditary Motor Neuropathy, Type Ii. Among its related pathways are mRNA Splicing - Major Pathway and mRNA Splicing - Minor Pathway. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and ATP-dependent RNA helicase activity.
UniProtKB/Swiss-Prot for DDX23 Gene
-
Involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DDX23 Gene
Genomics for DDX23 Gene
GeneHancer (GH) Regulatory Elements for DDX23 Gene
Promoters and enhancers for DDX23 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around DDX23 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for DDX23 Gene
Genomic Locations for DDX23 Gene
- chr12:48,829,756-48,852,842
- (GRCh38/hg38)
- Size:
- 23,087 bases
- Orientation:
- Minus strand
- chr12:49,223,539-49,246,625
- (GRCh37/hg19)
Genomic View for DDX23 Gene
Genes around DDX23 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q13.12 by Entrez Gene
- 12q13.12 by HGNC
- 12q13.12 by Ensembl
DDX23 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DDX23 Gene
Proteins for DDX23 Gene
-
Protein details for DDX23 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BUQ8-DDX23_HUMAN
- Recommended name:
- Probable ATP-dependent RNA helicase DDX23
- Protein Accession:
- Q9BUQ8
- B2R600
- B4DH15
- O43188
Protein attributes for DDX23 Gene
- Size:
- 820 amino acids
- Molecular mass:
- 95583 Da
- Quaternary structure:
-
- The phosphorylated form (by SRPK2) is a component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, WDR57, SNRNP40, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39. Identified in the spliceosome C complex. Interacts with ERBB4.
Protein Expression for DDX23 Gene
Post-translational modifications for DDX23 Gene
- In vitro phosphorylated by CLK1 and U1 snRNP-associated protein kinase. Phosphorylated by SRPK2 and this phosphorylation is required for its association with the tri-snRNP (U4/U6-U5 tri-small nuclear ribonucleoproteins) and subsequent spliceosomal B complex formation.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for DDX23 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for DDX23
- Novus Biologicals Antibodies for DDX23
- Invitrogen Antibodies for DDX23
- GeneTex DDX23 Antibody for DDX23
-
Boster Bio Antibodies for DDX23
Protein Products
-
OriGene Purified Proteins for DDX23
- Search Origene for MassSpec and Protein Over-expression Lysates for DDX23
- Origene Custom Protein Services for DDX23
- Search GeneTex for Proteins for DDX23
Assay Products
No data available for DME Specific Peptides for DDX23 Gene
Domains & Families for DDX23 Gene
Gene Families for DDX23 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for DDX23 Gene
Suggested Antigen Peptide Sequences for DDX23 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9BUQ8- Family:
-
- Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
Function for DDX23 Gene
Molecular function for DDX23 Gene
- UniProtKB/Swiss-Prot Function:
- Involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation.
- UniProtKB/Swiss-Prot CatalyticActivity:
- ATP + H(2)O = ADP + phosphate.
Enzyme Numbers (IUBMB) for DDX23 Gene
Phenotypes From GWAS Catalog for DDX23 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003723 | RNA binding | HDA | 22681889 |
| GO:0004004 | ATP-dependent RNA helicase activity | TAS | 9409622 |
| GO:0004386 | helicase activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 20858735 |
Phenotypes for DDX23 Gene
- GenomeRNAi human phenotypes for DDX23:
-
- Decreased vesicular stomatitis virus (VSV) infection
- Decreased HIV-1 infection
- Negative genetic interaction between BLM-/- and BLM+/+
- Negative genetic interaction between MUS81-/- and MUS81+/+
- Upregulation of Wnt/beta-catenin pathway after WNT3A stimulation
- Reduced mammosphere formation
- Decreased viability in esophageal squamous lineage
- Decreased shRNA abundance
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Decreased IL-8 secretion
Animal Model Products
-
Taconic Biosciences Mouse Models for DDX23
- Cyagen custom Knockout/knockin (KOKI) mouse models for DDX23
-
CRISPR Products
-
OriGene CRISPR knockouts for DDX23
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DDX23
- genomics-online: gRNA clones - Search results for available DDX23 gene related products
- Applied Biological Materials CRISPR for DDX23
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for DDX23
- GenScript: Design CRISPR guide RNA sequences for DDX23
miRNA for DDX23 Gene
- miRTarBase miRNAs that target DDX23
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DDX23
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DDX23
- genomics-online: shRNA clones - Search results for available DDX23 gene related products
Clone Products
- GenScript: Custom all cDNA clones Services for DDX23
- VectorBuilder custom plasmid, inducible vectors for DDX23
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DDX23
- genomics-online: cdna clones - Search results for available DDX23 gene related products
- orf clones - Search results for available DDX23 gene related products
- Applied Biological Materials Clones for DDX23
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for DDX23 Gene
Localization for DDX23 Gene
Subcellular locations from UniProtKB/Swiss-Prot for DDX23 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| plasma membrane | 2 |
| mitochondrion | 2 |
- Nucleoli (3)
- Nucleus (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA,TAS | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005681 | spliceosomal complex | IEA | -- |
| GO:0005682 | U5 snRNP | IDA | 9539711 |
| GO:0005730 | nucleolus | IDA,IBA | -- |
Pathways & Interactions for DDX23 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | mRNA Splicing - Major Pathway |
.79
|
.50
|
| 2 | Gene Expression |
.48
|
|
| 3 | mRNA Splicing - Minor Pathway | ||
Pathways by source for DDX23 Gene
5 Reactome pathways for DDX23 Gene
1 KEGG pathway for DDX23 Gene
Interacting Proteins for DDX23 Gene
Selected Interacting proteins:
Q9BUQ8-DDX23_HUMAN
ENSP00000310723
for DDX23 Gene via
IID
UniProtKB
MINT
STRING
GPS-Prot Interaction Network for DDX23
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000354 | cis assembly of pre-catalytic spliceosome | IC | 9539711 |
| GO:0000375 | RNA splicing, via transesterification reactions | TAS | 9409622 |
| GO:0000398 | mRNA splicing, via spliceosome | TAS | -- |
| GO:0006397 | mRNA processing | IEA | -- |
| GO:0008380 | RNA splicing | TAS | 9409622 |
No data available for SIGNOR curated interactions for DDX23 Gene
Drugs & Compounds for DDX23 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| ADP |
|
Full agonist, Agonist, Partial agonist, Antagonist, Gating inhibitor | 58-64-0 |
|
Transcripts for DDX23 Gene
mRNA/cDNA for DDX23 Gene
- (4) Selected AceView cDNA sequences:
- (6) Additional mRNA sequences :
- (1) REFSEQ mRNAs :
- (18) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000308025 3248 bps (uc001rsm.4)
- ENST00000547135 1377 bps (uc058njt.1)
- ENST00000547165 958 bps (uc058nju.1)
- ENST00000547290 750 bps (uc058njr.1)
- ENST00000547842 554 bps (uc058njp.1)
Unigene Clusters for DDX23 Gene
CRISPR Products
-
OriGene CRISPR knockouts for DDX23
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DDX23
- genomics-online: gRNA clones - Search results for available DDX23 gene related products
- Applied Biological Materials CRISPR for DDX23
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for DDX23
- GenScript: Design CRISPR guide RNA sequences for DDX23
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DDX23
- Browse OriGene Inhibitory RNA Products For DDX23
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DDX23
- genomics-online: shRNA clones - Search results for available DDX23 gene related products
Clone Products
- GenScript: Custom all cDNA clones Services for DDX23
- VectorBuilder custom plasmid, inducible vectors for DDX23
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DDX23
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DDX23
- genomics-online: cdna clones - Search results for available DDX23 gene related products
- orf clones - Search results for available DDX23 gene related products
- Applied Biological Materials Clones for DDX23
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: |
| ExUns: | 16 | ^ | 17a | · | 17b | ^ | 18a | · | 18b | ^ | 19a | · | 19b | ^ | 20a | · | 20b | ^ | 21a | · | 21b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||
| SP3: | |||||||||||||||||||||
| SP4: | |||||||||||||||||||||
| SP5: | |||||||||||||||||||||
| SP6: | |||||||||||||||||||||
| SP7: | |||||||||||||||||||||
| SP8: | |||||||||||||||||||||
| SP9: | |||||||||||||||||||||
| SP10: | |||||||||||||||||||||
| SP11: | |||||||||||||||||||||
| SP12: | - | ||||||||||||||||||||
| SP13: | - |
Expression for DDX23 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Epiblast (Early Embryonic Tissues)
- Epiblast Cells Epiblast
-
Spleen (Hematopoietic System)
-
Thymus (Hematopoietic System)
This gene is overexpressed in Peripheral blood mononuclear cells (14.1) and CD8 Tcells (8.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for DDX23 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of DDX23 Gene:
DDX23SOURCE GeneReport for Unigene cluster for DDX23 Gene:
Hs.130098Evidence on tissue expression from TISSUES for DDX23 Gene
- Nervous system(4.9)
- Lung(4.6)
Primer Products
-
OriGene qPCR primer pairs and template standards for DDX23
-
OriGene qPCR primer pairs for DDX23
- genomics-online: primer clones - Search results for available DDX23 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for DDX23 Gene
Orthologs for DDX23 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| chimpanzee (Pan troglodytes) |
Mammalia | DDX23 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | DDX23 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | DDX23 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | DDX23 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Ddx23 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ddx23 33 |
|
||
| chicken (Gallus gallus) |
Aves | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| DDX23 33 |
|
||||
| lizard (Anolis carolinensis) |
Reptilia | DDX23 34 |
|
OneToOne | |
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.24773 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ddx23 34 33 |
|
OneToOne | |
| wufi39b12 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | CG10333 34 33 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP007825 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | ddx-23 34 33 |
|
OneToOne | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | PRP28 36 34 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT2G33730 33 |
|
||
| soybean (Glycine max) |
eudicotyledons | Gma.3548 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os03g0708600 33 |
|
||
| Os.3228 33 |
|
||||
| barley (Hordeum vulgare) |
Liliopsida | Hv.2391 33 |
|
||
| wheat (Triticum aestivum) |
Liliopsida | Ta.3307 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne | |
| Cin.11344 33 |
|
||||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU02803 33 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | prp28 33 |
|
||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.11344 33 |
|
- Species where no ortholog for DDX23 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
Evolution for DDX23 Gene
- ENSEMBL:
- Gene Tree for DDX23 (if available)
- TreeFam:
- Gene Tree for DDX23 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for DDX23: view image
Paralogs for DDX23 Gene
(11) SIMAP similar genes for DDX23 Gene using alignment to 6 proteins:
- DDX23_HUMAN
- B4DH15_HUMAN
- F8VVA2_HUMAN
- F8W1J5_HUMAN
- H0YI52_HUMAN
- H0YIL9_HUMAN
Pseudogenes.org Pseudogenes for DDX23 Gene
No data available for Paralogs for DDX23 Gene
Variants for DDX23 Gene
| SNP ID | Clin | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000050240 | -- | 48,847,295(-) | T/C | intron_variant | |
| rs1000079795 | -- | 48,849,451(-) | C/G | intron_variant | |
| rs1000202162 | -- | 48,834,199(-) | G/A | intron_variant | |
| rs1000221416 | -- | 48,847,034(-) | C/T | intron_variant | |
| rs1000447660 | -- | 48,852,935(-) | G/C | upstream_transcript_variant |
Residual Variation Intolerance Score:
2.91% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.57;
12.25% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for DDX23 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- DDX23
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DDX23 Gene
Disorders for DDX23 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| distal hereditary motor neuropathy, type ii |
|
|
Search DDX23 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for DDX23
No data available for UniProtKB/Swiss-Prot and Genatlas for DDX23 Gene
Publications for DDX23 Gene
- The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p. (PMID: 9409622) Teigelkamp S … Lührmann R (RNA (New York, N.Y.) 1997) 2 3 4 22 58
- Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. (PMID: 18425142) Mathew R … Lührmann R (Nature structural & molecular biology 2008) 3 4 22 58
- The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro. (PMID: 9539711) Laggerbauer B … Lührmann R (Proceedings of the National Academy of Sciences of the United States of America 1998) 2 3 22 58
- Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways. (PMID: 20858735) Gilmore-Hebert M … Stern DF (Molecular cancer research : MCR 2010) 3 4 58
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen JV … Mann M (Cell 2006) 3 4 58
Products for DDX23 Gene
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- GenScript Custom Peptide Services for DDX23
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for DDX23
- Novus Biologicals proteins and lysates for DDX23
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Taconic Biosciences Mouse Models for DDX23
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- VectorBuilder custom plasmid, inducible vectors for DDX23
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DDX23
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 58 available DDX23 Antibodies ranked by validation data
- Compare Top DDX23 Antibodies
- antibodies-online: Search results for available DDX23 related products ranked by validation data
- antibodies-online: Search results for available DDX23 related products ranked by validation data
- GeneTex DDX23 Antibody for DDX23
- Search GeneTex for Proteins for DDX23
- genomics-online: cdna clones - Search results for available DDX23 gene related products
- orf clones - Search results for available DDX23 gene related products
- genomics-online: gRNA clones - Search results for available DDX23 gene related products
- genomics-online: primer clones - Search results for available DDX23 gene related products
- genomics-online: shRNA clones - Search results for available DDX23 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DDX23
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DDX23
- GeneCopoeia miRNA 3'UTR Target clone products for DDX23
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DDX23
- Boster Bio Antibodies for DDX23
- Browse Boster Bio ELISA Kits
Sources for DDX23 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio