Aliases for DDX18 Gene
External Ids for DDX18 Gene
Previous GeneCards Identifiers for DDX18 Gene
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein. [provided by RefSeq, Jul 2008]
GeneCards Summary for DDX18 Gene
DDX18 (DEAD-Box Helicase 18) is a Protein Coding gene. Diseases associated with DDX18 include Sennetsu Fever. Among its related pathways are Validated targets of C-MYC transcriptional activation. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and ATP-dependent RNA helicase activity. An important paralog of this gene is DDX10.
UniProtKB/Swiss-Prot Summary for DDX18 Gene
Probable RNA-dependent helicase.