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Aliases for DDX11L8 Gene

Aliases for DDX11L8 Gene

  • DEAD/H-Box Helicase 11 Like 8 2 3 5
  • DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 Like 8 2
  • DEAD/H (Asp-Glu-Ala-Asp/His) Box Helicase 11 Like 8 2
  • DEAD/H Box Protein 11-Like 8 4
  • EC 3.6.4.13 4

External Ids for DDX11L8 Gene

Previous GeneCards Identifiers for DDX11L8 Gene

  • GC00U928076
  • GC12P000091
  • GC12M000095

Summaries for DDX11L8 Gene

GeneCards Summary for DDX11L8 Gene

DDX11L8 (DEAD/H-Box Helicase 11 Like 8) is a Pseudogene.

UniProtKB/Swiss-Prot for DDX11L8 Gene

  • Putative DNA helicase.

Additional gene information for DDX11L8 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DDX11L8 Gene

Genomics for DDX11L8 Gene

GeneHancer (GH) Regulatory Elements for DDX11L8 Gene

Promoters and enhancers for DDX11L8 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I000013 Enhancer 0.9 Ensembl ENCODE 550.8 +1.4 1391 1 PKNOX1 NFIB FEZF1 ZIC2 GATA3 GLIS2 ZBTB48 PRDM10 ZNF444 FOS DDX11L8 LOC100288778
GH12I000010 Enhancer 0.5 ENCODE 550.8 -1.9 -1877 0.7 SP1 POLR3A MAX SIRT6 ZBTB33 DDX11L8
GH12I000030 Promoter 1 Ensembl 0.4 +18.7 18691 1.6 HDAC1 HDGF RB1 NFRKB ZBTB40 ZNF335 POLR2A GATAD2A MTA2 NR4A1 LOC100288778 DDX11L8
GH12I000021 Enhancer 0.6 ENCODE 0.4 +9.6 9617 1.2 CTCF BATF IRF4 TGIF2 ZNF512B ZNF366 IKZF1 NFE2 RUNX3 NFE2L2 DDX11L8 LOC100288778
GH12I000023 Enhancer 0.2 Ensembl 0.4 +11.3 11257 0.9 LOC100288778 DDX11L8
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around DDX11L8 on UCSC Golden Path with GeneCards custom track

Genomic Locations for DDX11L8 Gene

Genomic Locations for DDX11L8 Gene
chr12:12,310-14,520
(GRCh38/hg38)
Size:
2,211 bases
Orientation:
Plus strand
chr12:92,146-93,430
(GRCh37/hg19)

Genomic View for DDX11L8 Gene

Genes around DDX11L8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DDX11L8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DDX11L8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DDX11L8 Gene

Proteins for DDX11L8 Gene

  • Protein details for DDX11L8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MPP1-D11L8_HUMAN
    Recommended name:
    Putative ATP-dependent RNA helicase DDX11-like protein 8
    Protein Accession:
    A8MPP1

    Protein attributes for DDX11L8 Gene

    Size:
    907 amino acids
    Molecular mass:
    101811 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DDX11L8 Gene

Post-translational modifications for DDX11L8 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DDX11L8 Gene

Domains & Families for DDX11L8 Gene

Suggested Antigen Peptide Sequences for DDX11L8 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A8MPP1

UniProtKB/Swiss-Prot:

D11L8_HUMAN :
  • Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
Family:
  • Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
genes like me logo Genes that share domains with DDX11L8: view

No data available for Gene Families for DDX11L8 Gene

Function for DDX11L8 Gene

Molecular function for DDX11L8 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
ATP + H(2)O = ADP + phosphate.
UniProtKB/Swiss-Prot Function:
Putative DNA helicase.

Enzyme Numbers (IUBMB) for DDX11L8 Gene

Animal Model Products

Clone Products

No data available for Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DDX11L8 Gene

Localization for DDX11L8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DDX11L8 Gene

Nucleus, nucleolus.

No data available for Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for DDX11L8 Gene

Pathways & Interactions for DDX11L8 Gene

SuperPathways for DDX11L8 Gene

No Data Available

Interacting Proteins for DDX11L8 Gene

Selected Interacting proteins: A8MPP1-D11L8_HUMAN for DDX11L8 Gene via UniProtKB IID

Gene Ontology (GO) - Biological Process for DDX11L8 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DDX11L8 Gene

Drugs & Compounds for DDX11L8 Gene

(3) Drugs for DDX11L8 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
Water Approved Pharma 0
ATP Investigational Nutra Agonist 0

(1) Additional Compounds for DDX11L8 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • Adenosindiphosphorsaeure
  • Adenosine 5'-pyrophosphate
  • Adenosine diphosphate
  • Adenosine pyrophosphate
  • Adenosine-5'-diphosphate
Full agonist, Agonist 58-64-0
genes like me logo Genes that share compounds with DDX11L8: view

Transcripts for DDX11L8 Gene

mRNA/cDNA for DDX11L8 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for DDX11L8 Gene

No ASD Table

Relevant External Links for DDX11L8 Gene

GeneLoc Exon Structure for
DDX11L8
ECgene alternative splicing isoforms for
DDX11L8

Expression for DDX11L8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DDX11L8 Gene

mRNA differential expression in normal tissues according to GTEx for DDX11L8 Gene

This gene is overexpressed in Testis (x21.0), Whole Blood (x16.3), Small Intestine - Terminal Ileum (x5.5), Brain - Cerebellum (x5.2), and Brain - Cerebellar Hemisphere (x4.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for DDX11L8 Gene



NURSA nuclear receptor signaling pathways regulating expression of DDX11L8 Gene:

DDX11L8
genes like me logo Genes that share expression patterns with DDX11L8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DDX11L8 Gene

Orthologs for DDX11L8 Gene

Evolution for DDX11L8 Gene

ENSEMBL:
Gene Tree for DDX11L8 (if available)
TreeFam:
Gene Tree for DDX11L8 (if available)

No data available for Orthologs for DDX11L8 Gene

Paralogs for DDX11L8 Gene

(6) SIMAP similar genes for DDX11L8 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with DDX11L8: view

No data available for Paralogs for DDX11L8 Gene

Variants for DDX11L8 Gene

Additional Variant Information for DDX11L8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DDX11L8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for DDX11L8 Gene

Disorders for DDX11L8 Gene

No disorders were found for DDX11L8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for DDX11L8 Gene

Publications for DDX11L8 Gene

  1. DDX11L: a novel transcript family emerging from human subtelomeric regions. (PMID: 19476624) Costa V … Ciccodicola A (BMC genomics 2009) 2 3 58
  2. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer SE … Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team (Nature 2006) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. A physical interaction network of dengue virus and human proteins. (PMID: 21911577) Khadka S … LaCount DJ (Molecular & cellular proteomics : MCP 2011) 3

Products for DDX11L8 Gene

Sources for DDX11L8 Gene

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