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Aliases for DDN Gene
External Ids for DDN Gene
- HGNC: 24458
- Entrez Gene: 23109
- Ensembl: ENSG00000181418
- OMIM: 610588
- UniProtKB: O94850
Previous GeneCards Identifiers for DDN Gene
- GC12M049105
- GC12M047675
- GC12M049388
- GC12M046420
Summaries for DDN Gene
GeneCards Summary for DDN Gene
DDN (Dendrin) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include RNA polymerase II proximal promoter sequence-specific DNA binding and transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding.
UniProtKB/Swiss-Prot Summary for DDN Gene
-
Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein (By similarity).
Additional gene information for DDN Gene
- HGNC(24458)
- Entrez Gene(23109)
- Ensembl(ENSG00000181418)
- OMIM(610588)
- UniProtKB(O94850)
- Open Targets Platform(ENSG00000181418)
- Monarch Initiative
- Search for DDN at DataMed
- Search for DDN at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DDN Gene
Genomics for DDN Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for DDN Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around DDN on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for DDN
- Top Transcription factor binding sites by QIAGEN in the DDN gene promoter:
-
- AP-2alpha
- AP-2alphaA
- AP-2beta
- AP-2gamma
- C/EBPbeta
- CUTL1
- Egr-2
- HOXA3
- SREBP-1a
- SREBP-1b
Genomic Locations for DDN Gene
Genomic Locations for DDN Gene
- chr12:48,995,149-49,001,773
- (GRCh38/hg38)
- Size:
- 6,625 bases
- Orientation:
- Minus strand
- chr12:49,388,932-49,393,092
- (GRCh37/hg19)
- Size:
- 4,161 bases
- Orientation:
- Minus strand
Genomic View for DDN Gene
Genes around DDN on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q13.12 by HGNC
- 12q13.12 by Entrez Gene
- 12q13.12 by Ensembl
DDN Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DDN Gene
Proteins for DDN Gene
-
Protein details for DDN Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O94850-DEND_HUMAN
- Recommended name:
- Dendrin
- Protein Accession:
- O94850
Protein attributes for DDN Gene
- Size:
- 711 amino acids
- Molecular mass:
- 75996 Da
- Quaternary structure:
-
- Forms a ternary complex with MAGI2 and SH3KBP1; recruits DDN to the cytoplasm. Interacts with MAGI1. Interacts with ACTN1 and may interact with WWC1. Interacts with the podocyte slit diaphragm proteins CD2AP, NPHS1 and NPHS2; the interaction with CD2AP and NPHS1 is direct (By similarity).
- SequenceCaution:
-
- Sequence=BAA34469.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for DDN Gene
Post-translational modifications for DDN Gene
Other Protein References for DDN Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- antibodies-online: Search results for available Ddn related products ranked by validation data
Protein Products
-
OriGene Purified Proteins for DDN
- Search Origene for MassSpec and Protein Over-expression Lysates for DDN
- Origene Custom Protein Services for DDN
- antibodies-online: Search results for available Ddn related products ranked by validation data
Assay Products
- antibodies-online: Search results for available Ddn related products ranked by validation data
-
Signalway ELISA kits for DDN
No data available for DME Specific Peptides for DDN Gene
Domains & Families for DDN Gene
Gene Families for DDN Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for DDN Gene
- GenScript: Design optimal peptide antigens:
-
- Dendrin (B9EGD7_HUMAN)
- Dendrin (DEND_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for DDN Gene
Function for DDN Gene
Molecular function for DDN Gene
- UniProtKB/Swiss-Prot Function:
- Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein (By similarity).
Phenotypes From GWAS Catalog for DDN Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IBA | 21873635 |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | IBA | 21873635 |
| GO:0005515 | protein binding | IPI | 16464232 |
Phenotypes for DDN Gene
- MGI mutant phenotypes for DDN:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for DDN:
-
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- Increased gamma-H2AX phosphorylation
- Increased NF-kappaB reporter expression
- Increased epidermal growth factor (EGF) endocytosis, decreased endosome-nucleus distance (endosomes clustered in the perinuclear region)
- Actin fiber cells
Animal Models for DDN Gene
- MGI Knock Outs for DDN:
-
- Ddn Ddn<tm1Ktry>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for DDN - Select products 50% OFF >
- * DDN CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for DDN
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DDN
-
Santa Cruz Biotechnology (SCBT) CRISPR for DDN
miRNA for DDN Gene
- miRTarBase miRNAs that target DDN
-
- mmu-miR-541-5p (MIRT008231)
- mmu-miR-223-3p (MIRT009698)
- mmu-miR-340-5p (MIRT010411)
- mmu-let-7b-5p (MIRT012101)
- hsa-miR-335-5p (MIRT018142)
- hsa-miR-16-5p (MIRT051128)
- hsa-miR-7108-5p (MIRT478309)
- hsa-miR-548s (MIRT478310)
- hsa-miR-573 (MIRT478311)
- hsa-miR-3616-5p (MIRT478312)
- hsa-miR-663b (MIRT478313)
- hsa-miR-6799-5p (MIRT478314)
- hsa-miR-3926 (MIRT478315)
- hsa-miR-6851-5p (MIRT478316)
- hsa-miR-3689d (MIRT478317)
- hsa-miR-3934-3p (MIRT478318)
- hsa-miR-7854-3p (MIRT478319)
- hsa-miR-4480 (MIRT478320)
- hsa-miR-3188 (MIRT478321)
- hsa-miR-2467-5p (MIRT478322)
- hsa-miR-3975 (MIRT478323)
- hsa-miR-4795-5p (MIRT478324)
- hsa-miR-4738-3p (MIRT478325)
- hsa-miR-4649-3p (MIRT478326)
- hsa-miR-4518 (MIRT478327)
- hsa-miR-1266-5p (MIRT478328)
- hsa-miR-6754-5p (MIRT478329)
- hsa-miR-4441 (MIRT478330)
- hsa-miR-4270 (MIRT478331)
- hsa-miR-211-3p (MIRT478332)
- hsa-miR-4756-5p (MIRT478333)
- hsa-miR-1321 (MIRT478334)
- hsa-miR-4739 (MIRT478335)
- hsa-miR-4496 (MIRT478336)
- hsa-miR-485-5p (MIRT478337)
- hsa-miR-6884-5p (MIRT478338)
- hsa-miR-24-3p (MIRT478339)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DDN
- Browse OriGene Inhibitory RNA Products For DDN
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DDN
Clone Products
- Applied Biological Materials (abm): Clones for DDN - Select products 50% OFF >
- * DDN as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for DDN
- Addgene plasmids for DDN
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DDN
Cell Line Products
-
Horizon Cell Lines for DDN
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for DDN Gene
Localization for DDN Gene
Subcellular locations from UniProtKB/Swiss-Prot for DDN Gene
- Cell projection, dendritic spine membrane. Peripheral membrane protein. Cytoplasm. Endoplasmic reticulum membrane. Peripheral membrane protein. Cytoplasmic side. Perikaryon. Nucleus. Note=Enriched at the cytoplasmic insertion of the slit diaphragm into the foot process of podocytes and associated with polyribosomes in dendrites. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| plasma membrane | 4 |
| nucleus | 4 |
| endoplasmic reticulum | 3 |
| cytoskeleton | 2 |
| cytosol | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Cytosol (3)
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0005737 | cytoplasm | IBA,IDA | 16464232 |
| GO:0005783 | endoplasmic reticulum | IEA | -- |
| GO:0005789 | endoplasmic reticulum membrane | IEA | -- |
| GO:0005886 | plasma membrane | IEA | -- |
Pathways & Interactions for DDN Gene
Interacting Proteins for DDN Gene
Selected Interacting proteins:
O94850-DEND_HUMAN
ENSP00000390590
for DDN Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for DDN
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0045944 | positive regulation of transcription by RNA polymerase II | IBA | 21873635 |
No data available for Pathways by source and SIGNOR curated interactions for DDN Gene
Transcripts for DDN Gene
mRNA/cDNA for DDN Gene
- 1 REFSEQ mRNAs :
- 4 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000421952 3815 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for DDN - Select products 50% OFF >
- * DDN CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for DDN
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DDN
-
Santa Cruz Biotechnology (SCBT) CRISPR for DDN
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DDN
- Browse OriGene Inhibitory RNA Products For DDN
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DDN
Clone Products
- Applied Biological Materials (abm): Clones for DDN - Select products 50% OFF >
- * DDN as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for DDN
- Addgene plasmids for DDN
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DDN
Relevant External Links for DDN Gene
- GeneLoc Exon Structure for
- DDN
Expression for DDN Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Bone (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for DDN Gene
This gene is overexpressed in Muscle - Skeletal (x8.6), Brain - Amygdala (x6.0), Brain - Nucleus accumbens (basal ganglia) (x5.8), Brain - Anterior cingulate cortex (BA24) (x5.8), Brain - Cortex (x5.6), Brain - Putamen (basal ganglia) (x4.9), Brain - Hippocampus (x4.8), Brain - Frontal Cortex (BA9) (x4.6), and Brain - Caudate (basal ganglia) (x4.5).
This gene is overexpressed in Salivary gland (45.7) and Heart (23.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for DDN Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DDN
SOURCE GeneReport for Unigene cluster for DDN Gene:
Hs.591044mRNA Expression by UniProt/SwissProt for DDN Gene:
O94850-DEND_HUMAN
Tissue specificity:
Specifically expressed in brain and kidney. Expressed in kidney glomerular capillary loops (at protein level).
Evidence on tissue expression from TISSUES for DDN Gene
- Nervous system(4.7)
- Muscle(3.1)
- Kidney(2.2)
Primer Products
-
OriGene qPCR primer pairs for DDN
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for DDN Gene
Orthologs for DDN Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | DDN 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | DDN 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | DDN 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Ddn 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Ddn 30 |
|
||
| Lizard (Anolis carolinensis) |
Reptilia | DDN 31 |
|
OneToOne |
- Species where no ortholog for DDN was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for DDN Gene
- ENSEMBL:
- Gene Tree for DDN (if available)
- TreeFam:
- Gene Tree for DDN (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for DDN: view image
Paralogs for DDN Gene
No data available for Paralogs for DDN Gene
Variants for DDN Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for DDN Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 691427 | Uncertain Significance: Pyloric stenosis; Esophageal atresia | 48,996,865(-) | C/G | MISSENSE_VARIANT | |
| 776701 | Benign: not provided | 48,997,803(-) | G/C | MISSENSE_VARIANT | |
| rs10783299 | - | p.Glu661Gly |
Residual Variation Intolerance Score:
19.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.34;
85.35% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for DDN Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- DDN
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DDN Gene
Disorders for DDN Gene
Additional Disease Information for DDN
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for DDN Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DDN Gene
Publications for DDN Gene
- Dendrin expression in glomerulogenesis and in human minimal change nephrotic syndrome. (PMID: 18356187) Dunér F … Wernerson A (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2008) 3 4 23
- Postsynaptic recruitment of Dendrin depends on both dendritic mRNA transport and synaptic anchoring. (PMID: 16464232) Kremerskothen J … Barnekow A (Journal of neurochemistry 2006) 3 4 23
- Characterization of KIBRA, a novel WW domain-containing protein. (PMID: 12559952) Kremerskothen J … Barnekow A (Biochemical and biophysical research communications 2003) 3 4 23
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41
- CIN85 is localized at synapses and forms a complex with S-SCAM via dendrin. (PMID: 16751601) Kawata A … Hata Y (Journal of biochemistry 2006) 3 4
ExternalLinks
Products for DDN Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for DDN
- Search Origene for MassSpec and Protein Over-expression Lysates for DDN
- Origene Custom Protein Services for DDN
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DDN
- Browse OriGene Inhibitory RNA Products For DDN
- OriGene qPCR primer pairs for DDN
- OriGene CRISPR knockouts for DDN
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For DDN
- Sino Biological Human cDNA Clone for DDN
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- VectorBuilder Custom and pre-made DNA vectors for DDN (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for DDN (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for DDN (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for DDN CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for DDN
- Addgene plasmids for DDN
- antibodies-online: Search results for available Ddn related products ranked by validation data
- antibodies-online: Search results for available Ddn related products ranked by validation data
- antibodies-online: Search results for available Ddn related products ranked by validation data
- Horizon Cell Lines for DDN
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DDN
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DDN
- Search GeneCopoeia for miRNA 3'UTR Target clone products for DDN
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DDN
- Signalway ELISA kits for DDN
Sources for DDN Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB