Aliases for DCUN1D2 Gene
External Ids for DCUN1D2 Gene
Previous HGNC Symbols for DCUN1D2 Gene
Previous GeneCards Identifiers for DCUN1D2 Gene
GeneCards Summary for DCUN1D2 Gene
DCUN1D2 (Defective In Cullin Neddylation 1 Domain Containing 2) is a Protein Coding gene. Diseases associated with DCUN1D2 include Epidermolysis Bullosa Simplex With Nail Dystrophy and Optic Nerve Sheath Meningioma. An important paralog of this gene is DCUN1D1.
UniProtKB/Swiss-Prot Summary for DCUN1D2 Gene
Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.