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The protein encoded by this gene is dCTP pyrophosphatase, which converts dCTP to dCMP and inorganic pyrophosphate. The encoded protein also displays weak activity against dTTP and dATP, but none against dGTP. This protein may be responsible for eliminating excess dCTP after DNA synthesis and may prevent overmethylation of CpG islands. Three transcript variants, one protein-codi... See more...
Aliases for DCTPP1 Gene
Aliases for DCTPP1 Gene
External Ids for DCTPP1 Gene
- HGNC: 28777
- Entrez Gene: 79077
- Ensembl: ENSG00000179958
- OMIM: 615840
- UniProtKB: Q9H773
Previous GeneCards Identifiers for DCTPP1 Gene
- GC16M030343
- GC16M030344
- GC16M030435
- GC16M027997
Summaries for DCTPP1 Gene
-
The protein encoded by this gene is dCTP pyrophosphatase, which converts dCTP to dCMP and inorganic pyrophosphate. The encoded protein also displays weak activity against dTTP and dATP, but none against dGTP. This protein may be responsible for eliminating excess dCTP after DNA synthesis and may prevent overmethylation of CpG islands. Three transcript variants, one protein-coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]
GeneCards Summary for DCTPP1 Gene
DCTPP1 (DCTP Pyrophosphatase 1) is a Protein Coding gene. Diseases associated with DCTPP1 include Aspartylglucosaminuria and Otosclerosis. Among its related pathways are Metabolism and Metabolism of nucleotides. Gene Ontology (GO) annotations related to this gene include identical protein binding and pyrophosphatase activity.
UniProtKB/Swiss-Prot Summary for DCTPP1 Gene
-
Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
Additional gene information for DCTPP1 Gene
- HGNC(28777)
- Entrez Gene(79077)
- Ensembl(ENSG00000179958)
- OMIM(615840)
- UniProtKB(Q9H773)
- Open Targets Platform(ENSG00000179958)
- Search for DCTPP1 at DataMed
- Search for DCTPP1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DCTPP1 Gene
Genomics for DCTPP1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for DCTPP1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around DCTPP1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for DCTPP1
- Top Transcription factor binding sites by QIAGEN in the DCTPP1 gene promoter:
-
- AP-1
- AP-2alpha
- c-Fos
- c-Jun
- CBF(2)
- GATA-1
- IRF-1
- NF-Y
- Pax-4a
- Sp1
Genomic Locations for DCTPP1 Gene
Genomic Locations for DCTPP1 Gene
- chr16:30,423,615-30,430,030
- (GRCh38/hg38)
- Size:
- 6,416 bases
- Orientation:
- Minus strand
- chr16:30,434,940-30,441,396
- (GRCh37/hg19)
- Size:
- 6,457 bases
- Orientation:
- Minus strand
Genomic View for DCTPP1 Gene
Genes around DCTPP1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p11.2 by HGNC
- 16p11.2 by Entrez Gene
- 16p11.2 by Ensembl
DCTPP1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DCTPP1 Gene
Proteins for DCTPP1 Gene
-
Protein details for DCTPP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H773-DCTP1_HUMAN
- Recommended name:
- dCTP pyrophosphatase 1
- Protein Accession:
- Q9H773
Protein attributes for DCTPP1 Gene
- Size:
- 170 amino acids
- Molecular mass:
- 18681 Da
- Cofactor:
- Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
- Quaternary structure:
-
- Homotetramer.
Protein Expression for DCTPP1 Gene
Post-translational modifications for DCTPP1 Gene
Other Protein References for DCTPP1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences DCTPP1 / XTP3TPA Antibody
-
Custom Antibody ServicesOriGene Antibodies for DCTPP1
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- Invitrogen Antibodies for DCTPP1 (AFLGC-DCTPP1)
-
Santa Cruz Biotechnology (SCBT) Antibodies for DCTPP1
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Protein Products
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- ProSpec Recombinant Proteins for DCTPP1
- antibodies-online: Show 9 available DCTPP1 Proteins ranked by validation data
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-
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-
Signalway Proteins for DCTPP1
-
Abcam proteins for DCTPP1
Assay Products
- antibodies-online: Show 7 available DCTPP1 Elisa Kits ranked by validation data
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-
Quality Products:
No data available for DME Specific Peptides for DCTPP1 Gene
Domains & Families for DCTPP1 Gene
Gene Families for DCTPP1 Gene
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for DCTPP1 Gene
- GenScript: Design optimal peptide antigens:
-
- XTP3-transactivated gene A protein (DCTP1_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for DCTPP1 Gene
Function for DCTPP1 Gene
Molecular function for DCTPP1 Gene
- UniProtKB/Swiss-Prot Function:
- Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=dCTP + H2O = dCMP + diphosphate + H(+); Xref=Rhea:RHEA:22636, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, ChEBI:CHEBI:57566, ChEBI:CHEBI:61481; EC=3.6.1.12; Evidence={ECO:0000269|PubMed:24467396};.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated by an increase in cellular dCTP pool.
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=47.6 uM for dCTP (at pH 8.0 and 25 degrees Celsius) {ECO:0000269|PubMed:24467396}; KM=65 uM for dTTP (at pH 8.0 and 25 degrees Celsius) {ECO:0000269|PubMed:24467396}; KM=79.3 uM for dATP (at pH 8.0 and 25 degrees Celsius) {ECO:0000269|PubMed:24467396}; KM=75.9 uM for dUTP (at pH 8.0 and 25 degrees Celsius) {ECO:0000269|PubMed:24467396}; KM=16.8 uM for 5I-dCTP (at pH 8.0 and 25 degrees Celsius) {ECO:0000269|PubMed:24467396}; KM=36.5 uM for 5Br-dCTP (at pH 8.0 and 25 degrees Celsius) {ECO:0000269|PubMed:24467396}; KM=33.3 uM for 5me-dCTP (at pH 8.0 and 25 degrees Celsius) {ECO:0000269|PubMed:24467396}; KM=62.9 uM for 5hme-dCTP (at pH 8.0 and 25 degrees Celsius) {ECO:0000269|PubMed:24467396}; KM=9.2 uM for 5fo-dCTP (at pH 8.0 and 25 degrees Celsius) {ECO:0000269|PubMed:24467396}; KM=142.9 uM for CTP (at pH 8.0 and 25 degrees Celsius) {ECO:0000269|PubMed:24467396};
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Inhibited by the reaction end product PPi. Inhibited by dCDP. Inhibited by triptolide.
Enzyme Numbers (IUBMB) for DCTPP1 Gene
Phenotypes From GWAS Catalog for DCTPP1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0000287 | magnesium ion binding | IEA,ISS | -- |
| GO:0005515 | protein binding | IPI | 16189514 |
| GO:0016462 | pyrophosphatase activity | IEA | -- |
| GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for DCTPP1 Gene
Animal Model Products
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CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for DCTPP1 - Select products 50% OFF >
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miRNA for DCTPP1 Gene
- miRTarBase miRNAs that target DCTPP1
-
- hsa-let-7b-5p (MIRT005221)
- hsa-miR-1-3p (MIRT023878)
- hsa-miR-34a-5p (MIRT025514)
- hsa-miR-26b-5p (MIRT029875)
- hsa-miR-615-3p (MIRT040115)
- hsa-miR-106b-5p (MIRT044359)
- hsa-miR-17-5p (MIRT050878)
- hsa-miR-8081 (MIRT544897)
- hsa-miR-6869-5p (MIRT544898)
- hsa-miR-5696 (MIRT544899)
- hsa-miR-4775 (MIRT544900)
- hsa-miR-616-3p (MIRT544901)
- hsa-miR-4729 (MIRT544902)
- hsa-miR-513b-3p (MIRT544903)
- hsa-miR-573 (MIRT551402)
- hsa-miR-3616-5p (MIRT551403)
- hsa-miR-298 (MIRT551404)
- hsa-miR-4795-5p (MIRT551405)
- hsa-miR-519c-3p (MIRT551406)
- hsa-miR-519b-3p (MIRT551407)
- hsa-miR-519a-3p (MIRT551408)
- hsa-miR-149-5p (MIRT718598)
- hsa-miR-422a (MIRT718599)
- hsa-miR-378i (MIRT718600)
- hsa-miR-378h (MIRT718601)
- hsa-miR-378f (MIRT718602)
- hsa-miR-378e (MIRT718603)
- hsa-miR-378d (MIRT718604)
- hsa-miR-378c (MIRT718605)
- hsa-miR-378b (MIRT718606)
- hsa-miR-378a-3p (MIRT718607)
- hsa-miR-4638-3p (MIRT718608)
- hsa-miR-1324 (MIRT718609)
miRNA Products
Inhibitory RNA Products
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Clone Products
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Cell Line Products
-
Horizon Cell Lines for DCTPP1
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for DCTPP1 Gene
Localization for DCTPP1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for DCTPP1 Gene
- Mitochondrion. Nucleus. Cytoplasm, cytosol.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| nucleus | 5 |
| cytosol | 5 |
| plasma membrane | 1 |
| extracellular | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA,IDA | 24467396 |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005739 | mitochondrion | IEA,IDA | 24467396 |
| GO:0005829 | cytosol | IBA,ISS | -- |
Pathways & Interactions for DCTPP1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism |
.40
|
|
| 2 | Metabolism of nucleotides | ||
| 3 | Synthesis and interconversion of nucleotide di- and triphosphates | ||
Pathways by source for DCTPP1 Gene
3 Reactome pathways for DCTPP1 Gene
2 KEGG pathways for DCTPP1 Gene
Interacting Proteins for DCTPP1 Gene
Selected Interacting proteins:
Q9H773-DCTP1_HUMAN
ENSP00000322524
for DCTPP1 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for DCTPP1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006253 | dCTP catabolic process | IMP | 24467396 |
| GO:0009143 | nucleoside triphosphate catabolic process | ISS | -- |
| GO:0042262 | DNA protection | IBA,IMP | 24467396 |
| GO:0046076 | NOT dTTP catabolic process | IMP | 24467396 |
Drugs & Compounds for DCTPP1 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| pyrophosphate |
|
14000-31-8 |
|
(1) ApexBio Compounds for DCTPP1 Gene
| Compound | Action | Cas Number |
|---|---|---|
| Triptonide | 38647-11-9 |
Transcripts for DCTPP1 Gene
mRNA/cDNA for DCTPP1 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000319285 1181 nts (view in UCSC)
- ENST00000567983 801 nts (view in UCSC)
- ENST00000568434 853 nts (view in UCSC)
- ENST00000568973 878 nts (view in UCSC)
- ENST00000565758 749 nts (view in UCSC)
CRISPR Products
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-
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-
Santa Cruz Biotechnology (SCBT) CRISPR for DCTPP1
miRNA Products
Inhibitory RNA Products
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Clone Products
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| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||
| SP2: | - | - | |||||||||||||||||
| SP3: | - | ||||||||||||||||||
| SP4: |
Relevant External Links for DCTPP1 Gene
- GeneLoc Exon Structure for
- DCTPP1
Expression for DCTPP1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Colon (Gastrointestinal Tract)
This gene is overexpressed in Lung (8.5) and Peripheral blood mononuclear cells (7.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for DCTPP1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DCTPP1
SOURCE GeneReport for Unigene cluster for DCTPP1 Gene:
Hs.632191Evidence on tissue expression from TISSUES for DCTPP1 Gene
- Nervous system(2.4)
Primer Products
-
OriGene qPCR primer pairs for DCTPP1
-
OriGene qPCR primer pairs and template standards for DCTPP1
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for DCTPP1 Gene
Orthologs for DCTPP1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | DCTPP1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | DCTPP1 30 |
|
||
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| Cow (Bos Taurus) |
Mammalia | DCTPP1 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Dctpp1 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Dctpp1 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | DCTPP1 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | DCTPP1 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | DCTPP1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | dctpp1 30 |
|
||
| Str.5848 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | zgc:73273 30 |
|
||
| DCTPP1 31 |
|
OneToOne | |||
| zgc73273 30 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.1175 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os02g0479300 30 |
|
- Species where no ortholog for DCTPP1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for DCTPP1 Gene
- ENSEMBL:
- Gene Tree for DCTPP1 (if available)
- TreeFam:
- Gene Tree for DCTPP1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for DCTPP1: view image
Paralogs for DCTPP1 Gene
No data available for Paralogs for DCTPP1 Gene
Variants for DCTPP1 Gene
Residual Variation Intolerance Score:
75.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.21;
24.34% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for DCTPP1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- DCTPP1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Structural Variations from Database of Genomic Variants (DGV) for DCTPP1 Gene
Disorders for DCTPP1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| aspartylglucosaminuria |
|
|
| otosclerosis |
|
|
Search DCTPP1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for DCTPP1
No data available for UniProtKB/Swiss-Prot and Genatlas for DCTPP1 Gene
Publications for DCTPP1 Gene
- Dimeric dUTPases, HisE, and MazG belong to a new superfamily of all-alpha NTP pyrophosphohydrolases with potential "house-cleaning" functions. (PMID: 15740738) Moroz OV … Galperin MY (Journal of molecular biology 2005) 2 3 23
- The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells. (PMID: 24467396) Requena CE … González-Pacanowska D (The Biochemical journal 2014) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools. (PMID: 31377845) Martínez-Arribas B … González-Pacanowska D (Cellular and molecular life sciences : CMLS 2020) 3
- PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling. (PMID: 31091453) Shami Shah A … Baskin JM (Cell reports 2019) 3
ExternalLinks
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- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DCTPP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DCTPP1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for DCTPP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DCTPP1
- Signalway Proteins for DCTPP1
Sources for DCTPP1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB