Aliases for DCT Gene
External Ids for DCT Gene
Previous HGNC Symbols for DCT Gene
Previous GeneCards Identifiers for DCT Gene
GeneCards Summary for DCT Gene
DCT (Dopachrome Tautomerase) is a Protein Coding gene. Diseases associated with DCT include Amelanotic Melanoma and Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 1. Among its related pathways are Neural Crest Differentiation and Aldosterone synthesis and secretion. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and dopachrome isomerase activity. An important paralog of this gene is TYRP1.
UniProtKB/Swiss-Prot Summary for DCT Gene
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA) (PubMed:8306979). Involved in regulating eumelanin and phaeomelanin levels.