Aliases for DCST1 Gene
External Ids for DCST1 Gene
Previous GeneCards Identifiers for DCST1 Gene
This gene encodes a protein with a domain similar to one found in dendritic cells (PMID:11169400) which play a key role in antigen processing and display for immune responses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
GeneCards Summary for DCST1 Gene
DCST1 (DC-STAMP Domain Containing 1) is a Protein Coding gene. An important paralog of this gene is DCST2.
UniProtKB/Swiss-Prot for DCST1 Gene
E3 ubiquitin-protein ligase which mediates Lys-48-linked ubiquitination of STAT2 and induces its proteosomal degradation thereby negatively regulating type-I-interferon signaling.