Aliases for DAZAP1 Gene
External Ids for DAZAP1 Gene
Previous GeneCards Identifiers for DAZAP1 Gene
In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for DAZAP1 Gene
DAZAP1 (DAZ Associated Protein 1) is a Protein Coding gene. Diseases associated with DAZAP1 include Azoospermia and Infertility. Among its related pathways are mRNA surveillance pathway. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is RBMX.
UniProtKB/Swiss-Prot Summary for DAZAP1 Gene
RNA-binding protein, which may be required during spermatogenesis.