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Aliases for DARS1-AS1 Gene
Data sources for DARS1-AS1 Gene:
Subcategory (RNA class) for DARS1-AS1 Gene
lncRNA
Aliases for DARS1-AS1 Gene
- DARS1 Antisense RNA 1 (HGNC, NCBI Entrez Gene, Ensembl)
- DARS Antisense RNA 1 (HGNC, NCBI Entrez Gene)
- DARS-AS1 (NCBI Entrez Gene, LNCipedia)
- NONHSAG029377.2 (NONCODE)
- HSALNG0019085 (LncBook)
- DARS1-AS1 (Ensembl)
External Ids for DARS1-AS1 Gene
- HGNC: 40170
- NCBI Entrez Gene: 101928243
- Ensembl: ENSG00000231890
Previous HGNC Symbols for DARS1-AS1 Gene
- DARS-AS1
Summaries for DARS1-AS1 Gene
GeneCards Summary for DARS1-AS1 Gene
DARS1-AS1 (DARS1 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with DARS1-AS1 include Glioma Susceptibility 1.
Additional gene information for DARS1-AS1 Gene
- HGNC (40170)
- NCBI Entrez Gene (101928243)
- Ensembl (ENSG00000231890)
- Open Targets Platform(ENSG00000231890)
- Search for DARS1-AS1 at DataMed
- Search for DARS1-AS1 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DARS1-AS1 Gene
Genomics for DARS1-AS1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for DARS1-AS1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around DARS1-AS1 on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for DARS1-AS1 Gene
Latest Assembly
- chr2:135,985,051-136,022,593
- (GRCh38/hg38)
- Size:
- 37,543 bases
- Orientation:
- Plus strand
Previous Assembly
- chr2:136,742,746-136,765,112
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 22,367 bases
- Orientation:
- Plus strand
- chr2:136,742,746-136,779,888
- (GRCh37/hg19 by Ensembl)
- Size:
- 37,143 bases
- Orientation:
- Plus strand
Genomic View for DARS1-AS1 Gene
Genes around DARS1-AS1 on UCSC Golden Path with GeneCards custom track
DARS1-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
- Cytogenetic band:
-
- 2q21.3 by HGNC
- 2q21.3 by Entrez Gene
- 2q21.3 by Ensembl
DARS1-AS1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DARS1-AS1 Gene
Proteins for DARS1-AS1 Gene
Post-translational modifications for DARS1-AS1 Gene
No Post-translational modifications
No data available for DME Specific Peptides for DARS1-AS1 Gene
Domains & Families for DARS1-AS1 Gene
Gene Families for DARS1-AS1 Gene
- HGNC:
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for DARS1-AS1 Gene
Function for DARS1-AS1 Gene
Phenotypes From GWAS Catalog for DARS1-AS1 Gene
CRISPR products for research
Inhibitory RNAs for research
Clone products for research
Cell Lines for research
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DARS1-AS1 Gene
Localization for DARS1-AS1 Gene
| Compartment | Confidence |
|---|---|
| mitochondrion | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for DARS1-AS1 Gene
Transcripts for DARS1-AS1 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for DARS1-AS1 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS00003C5F2D_9606 | lncRNA | 1426 | 4 |
Ensembl: ENST00000594219 (view in UCSC) , LncBook: HSALNT0040277, LNCipedia: DARS-AS1:9, NONCODE: NONHSAT182720.1, |
| URS00005DB95A_9606 | lncRNA | 1394 | 4 |
Ensembl: ENST00000597450 (view in UCSC) , LncBook: HSALNT0040287, LNCipedia: DARS-AS1:16, NONCODE: NONHSAT074619.2, |
| URS0000811738_9606 | lncRNA | 962 | 4 |
Ensembl: ENST00000399447 (view in UCSC) , LncBook: HSALNT0040304, LNCipedia: DARS-AS1:27, NONCODE: NONHSAT182725.1, |
| URS00008120CC_9606 | lncRNA | 923 | 4 |
Ensembl: ENST00000629483 (view in UCSC) , LncBook: HSALNT0040308, LNCipedia: DARS-AS1:30, NONCODE: NONHSAT182726.1, |
| URS0000811E69_9606 | lncRNA | 861 | 4 |
Ensembl: ENST00000609237 (view in UCSC) , LncBook: HSALNT0040278, LNCipedia: DARS-AS1:11, NONCODE: NONHSAT182719.1, |
DARS1-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for DARS1-AS1 Gene
- 5 NCBI additional mRNA sequence :
CRISPR products for research
Inhibitory RNAs for research
Clone products for research
Relevant External Links for DARS1-AS1 Gene
- GeneLoc Exon Structure for
- DARS1-AS1
Expression for DARS1-AS1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DARS1-AS1
No Expression Related Data Available
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DARS1-AS1 Gene
Orthologs for DARS1-AS1 Gene
No data available for Orthologs for DARS1-AS1 Gene
Paralogs for DARS1-AS1 Gene
No data available for Paralogs for DARS1-AS1 Gene
Variants for DARS1-AS1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for DARS1-AS1 Gene
| SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs11548872 | Benign: not specified | 135,985,510(+) |
G/C NM_001349.4(DARS1):c.-42C>G |
NON_CODING_TRANSCRIPT_VARIANT,FIVE_PRIME_UTR | |
| rs551090724 | Uncertain Significance: not provided | 135,985,447(+) |
G/GGCTGGC NM_001349.4(DARS1):c.10_15GCCAGC[3] (p.4_5AS[3]) |
NON_CODING_TRANSCRIPT_VARIANT,INFRAME_INSERTION,FIVE_PRIME_UTR |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Additional Variant Information for DARS1-AS1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- DARS1-AS1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for DARS1-AS1 Gene
Disorders for DARS1-AS1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| glioma susceptibility 1 |
|
Search DARS1-AS1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for DARS1-AS1
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for DARS1-AS1 Gene
Publications for DARS1-AS1 Gene
- Hypoxia-induced long non-coding RNA DARS-AS1 regulates RBM39 stability to promote myeloma malignancy. (PMID: 31289203) Tong J … Yan H (Haematologica 2020) 2 3
- Novel lnc RNA regulated by HIF-1 inhibits apoptotic cell death in the renal tubular epithelial cells under hypoxia. (PMID: 28420760) Mimura I … Nangaku M (Physiological reports 2017) 2 3
- LncRNA DARS-AS1 regulates microRNA-129 to promote malignant progression of thyroid cancer. (PMID: 31841198) Zheng W … Tian GY (European review for medical and pharmacological sciences 2019) 3
- The Use of Three Long Non-Coding RNAs as Potential Prognostic Indicators of Astrocytoma. (PMID: 26252651) Zhi F … Yang Y (PloS one 2015) 74
- Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R … Stanton LW (Nature biotechnology 2004) 3
Products for DARS1-AS1 Gene
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- Custom Antibody Services
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- Custom Assay Services
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- Origene Custom Protein Services for DARS1-AS1
- Browse OriGene Inhibitory RNA Products For DARS1-AS1
- Browse OriGene qPCR primer pairs and template standards
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For DARS1-AS1
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
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- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for DARS1-AS1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for DARS1-AS1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for DARS1-AS1
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for DARS1-AS1
Sources for DARS1-AS1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB