Aliases for DARS1-AS1 Gene

Data sources for DARS1-AS1 Gene:

Subcategory (RNA class) for DARS1-AS1 Gene

lncRNA

Aliases for DARS1-AS1 Gene

External Ids for DARS1-AS1 Gene

Previous HGNC Symbols for DARS1-AS1 Gene

  • DARS-AS1

Summaries for DARS1-AS1 Gene

GeneCards Summary for DARS1-AS1 Gene

DARS1-AS1 (DARS1 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with DARS1-AS1 include Glioma Susceptibility 1.

Additional gene information for DARS1-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DARS1-AS1 Gene

Genomics for DARS1-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for DARS1-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J135983 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 250.7 -0.1 -86 3.7 ZSCAN16 CHD2 TBP ZBTB10 SP1 MXD4 NR2C1 MNT IKZF1 BRCA1 DARS1 DARS1-AS1 lnc-MCM6-2 UBXN4 MCM6 CXCR4
GH02J136211 Enhancer 1.2 FANTOM5 ENCODE dbSUPER 4 +229.4 229429 5.9 CEBPA CEBPB MAX EP300 EBF1 RAD21 CTBP1 RARA SMARCA5 SMC3 LOC107985947 lnc-CXCR4-5 lnc-UBXN4-13 CXCR4 MCM6 DARS1-AS1 UBXN4 THSD7B
GH02J136253 Enhancer 1.2 FANTOM5 ENCODE dbSUPER 4.1 +269.9 269938 3.2 BCL11A GABPA TRIM22 EBF1 SMC3 SMARCA5 MAX NFE2 SPI1 BHLHE40 HSALNG0019102 CXCR4 R3HDM1 MCM6 DARS1-AS1 HSALNG0019103 lnc-UBXN4-13 THSD7B
GH02J136005 Enhancer 1.2 FANTOM5 ENCODE dbSUPER 0.3 +22.9 22852 4.7 BCL11A GABPA TRIM22 IRF4 MAFF EBF1 ZNF316 CBFB SPI1 NFE2 CXCR4 DARS1 MCM6 UBXN4 HSALNG0019086 DARS1-AS1
GH02J135997 Enhancer 1 Ensembl ENCODE dbSUPER 0.4 +14.7 14650 6.6 CTCF TRIM22 MAFF EBF1 YY1 ZNF316 RAD21 PKNOX1 IKZF1 MAFK DARS1 CXCR4 DARS1-AS1 HSALNG0019086
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around DARS1-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for DARS1-AS1 Gene

Latest Assembly
chr2:135,985,051-136,022,593
(GRCh38/hg38)
Size:
37,543 bases
Orientation:
Plus strand

Previous Assembly
chr2:136,742,746-136,765,112
(GRCh37/hg19 by Entrez Gene)
Size:
22,367 bases
Orientation:
Plus strand

chr2:136,742,746-136,779,888
(GRCh37/hg19 by Ensembl)
Size:
37,143 bases
Orientation:
Plus strand

Genomic View for DARS1-AS1 Gene

Genes around DARS1-AS1 on UCSC Golden Path with GeneCards custom track
DARS1-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
DARS1-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DARS1-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DARS1-AS1 Gene

Proteins for DARS1-AS1 Gene

Post-translational modifications for DARS1-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DARS1-AS1 Gene

Domains & Families for DARS1-AS1 Gene

Gene Families for DARS1-AS1 Gene

genes like me logo Genes that share domains with DARS1-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for DARS1-AS1 Gene

Function for DARS1-AS1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DARS1-AS1 Gene

Localization for DARS1-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DARS1-AS1 gene
Compartment Confidence
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for DARS1-AS1 Gene

Pathways & Interactions for DARS1-AS1 Gene

PathCards logo

SuperPathways for DARS1-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for DARS1-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for DARS1-AS1 Gene

Drugs & Compounds for DARS1-AS1 Gene

No Compound Related Data Available

Transcripts for DARS1-AS1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for DARS1-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00003C5F2D_9606 lncRNA 1426 4

Ensembl: ENST00000594219 (view in UCSC) ,

LncBook: HSALNT0040277,

LNCipedia: DARS-AS1:9,

NONCODE: NONHSAT182720.1,

URS00005DB95A_9606 lncRNA 1394 4

Ensembl: ENST00000597450 (view in UCSC) ,

LncBook: HSALNT0040287,

LNCipedia: DARS-AS1:16,

NONCODE: NONHSAT074619.2,

URS0000811738_9606 lncRNA 962 4

Ensembl: ENST00000399447 (view in UCSC) ,

LncBook: HSALNT0040304,

LNCipedia: DARS-AS1:27,

NONCODE: NONHSAT182725.1,

URS00008120CC_9606 lncRNA 923 4

Ensembl: ENST00000629483 (view in UCSC) ,

LncBook: HSALNT0040308,

LNCipedia: DARS-AS1:30,

NONCODE: NONHSAT182726.1,

URS0000811E69_9606 lncRNA 861 4

Ensembl: ENST00000609237 (view in UCSC) ,

LncBook: HSALNT0040278,

LNCipedia: DARS-AS1:11,

NONCODE: NONHSAT182719.1,

DARS1-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for DARS1-AS1 Gene

5 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for DARS1-AS1 Gene

No ASD Table

Relevant External Links for DARS1-AS1 Gene

GeneLoc Exon Structure for
DARS1-AS1

Expression for DARS1-AS1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DARS1-AS1

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DARS1-AS1 Gene

Orthologs for DARS1-AS1 Gene

Evolution for DARS1-AS1 Gene

ENSEMBL:
Gene Tree for DARS1-AS1 (if available)
TreeFam:
Gene Tree for DARS1-AS1 (if available)

No data available for Orthologs for DARS1-AS1 Gene

Paralogs for DARS1-AS1 Gene

No data available for Paralogs for DARS1-AS1 Gene

Variants for DARS1-AS1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for DARS1-AS1 Gene

SNP ID Clinical significance and condition Chr 02 pos Variation AA Info Type
rs11548872 Benign: not specified 135,985,510(+) G/C
NM_001349.4(DARS1):c.-42C>G
NON_CODING_TRANSCRIPT_VARIANT,FIVE_PRIME_UTR
rs551090724 Uncertain Significance: not provided 135,985,447(+) G/GGCTGGC
NM_001349.4(DARS1):c.10_15GCCAGC[3] (p.4_5AS[3])
NON_CODING_TRANSCRIPT_VARIANT,INFRAME_INSERTION,FIVE_PRIME_UTR

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for DARS1-AS1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Additional Variant Information for DARS1-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DARS1-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for DARS1-AS1 Gene

Disorders for DARS1-AS1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for DARS1-AS1 Gene - From: LNC

Disorder Aliases PubMed IDs
glioma susceptibility 1
  • glm1
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for DARS1-AS1

genes like me logo Genes that share disorders with DARS1-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for DARS1-AS1 Gene

Publications for DARS1-AS1 Gene

  1. Hypoxia-induced long non-coding RNA DARS-AS1 regulates RBM39 stability to promote myeloma malignancy. (PMID: 31289203) Tong J … Yan H (Haematologica 2020) 2 3
  2. Novel lnc RNA regulated by HIF-1 inhibits apoptotic cell death in the renal tubular epithelial cells under hypoxia. (PMID: 28420760) Mimura I … Nangaku M (Physiological reports 2017) 2 3
  3. LncRNA DARS-AS1 regulates microRNA-129 to promote malignant progression of thyroid cancer. (PMID: 31841198) Zheng W … Tian GY (European review for medical and pharmacological sciences 2019) 3
  4. The Use of Three Long Non-Coding RNAs as Potential Prognostic Indicators of Astrocytoma. (PMID: 26252651) Zhi F … Yang Y (PloS one 2015) 74
  5. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R … Stanton LW (Nature biotechnology 2004) 3

Products for DARS1-AS1 Gene

Sources for DARS1-AS1 Gene