Aliases for DAP Gene
External Ids for DAP Gene
Previous GeneCards Identifiers for DAP Gene
This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
GeneCards Summary for DAP Gene
DAP (Death Associated Protein) is a Protein Coding gene. Diseases associated with DAP include Refractory Hairy Cell Leukemia and Refractory Hematologic Cancer. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include death domain binding.
UniProtKB/Swiss-Prot Summary for DAP Gene
Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death.