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Aliases for CYTOR Gene

Subcategory (RNA class) for CYTOR Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for CYTOR Gene

  • Cytoskeleton Regulator RNA 2 3 5
  • Long Intergenic Non-Protein Coding RNA 152 2 3
  • Chromosome 2 Open Reading Frame 59 2
  • Non-Protein Coding RNA 152 2
  • NCRNA00152 3
  • LINC00152 3
  • C2orf59 3

External Ids for CYTOR Gene

Previous HGNC Symbols for CYTOR Gene

  • C2orf59
  • NCRNA00152
  • LINC00152

Summaries for CYTOR Gene

Entrez Gene Summary for CYTOR Gene

  • This gene produces a long non-coding RNA that is overexpressed in cancer cells and promotes cell proliferation and epithelial-mesenchymal transition. This RNA may bind enhancer of zeste homolog 2 and participate in the transcriptional silencing of tumor suppressor genes. It may act as a sponge for microRNAs. Alternatively spliced variants have been observed. [provided by RefSeq, Dec 2017]

GeneCards Summary for CYTOR Gene

CYTOR (Cytoskeleton Regulator RNA) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with CYTOR include Clear Cell Renal Cell Carcinoma and Gallbladder Cancer.

Additional gene information for CYTOR Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYTOR Gene

Genomics for CYTOR Gene

GeneHancer (GH) Regulatory Elements for CYTOR Gene

Promoters and enhancers for CYTOR Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J087452 Promoter/Enhancer 1.6 Ensembl ENCODE dbSUPER 650.7 +0.1 66 5.2 HDAC1 ATF1 FOXA2 TAF9B NFRKB ARID4B SIN3A FEZF1 POLR2B ZNF366 CYTOR ENSG00000284879 ENSG00000231259 LINC01943
GH02J087504 Enhancer 1.3 Ensembl ENCODE dbSUPER 15.3 +58.3 58338 17.4 HDAC1 PKNOX1 ATF1 FOXA2 ARNT BMI1 YY1 TCF12 POLR2B ATF7 CYTOR LOC102724642 KRCC1 LOC730268 GC02M087530 LOC101928152 ENSG00000284879
GH02J087482 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 7.9 +30.7 30719 5.8 BCOR HDAC1 PKNOX1 KLF1 ZSCAN4 NFXL1 ZNF121 ZFHX2 GATA3 EGR1 LOC101928152 CYTOR LOC730268 LINC01943 ENSG00000284879
GH02J087533 Enhancer 0.6 Ensembl dbSUPER 11.8 +79.3 79320 2.6 PKNOX1 IKZF1 CYTOR GC02M087530 GC02M087565 ENSG00000284879
GH02J087468 Enhancer 1 Ensembl ENCODE dbSUPER 5.9 +15.3 15320 3.4 SRF L3MBTL2 MNT DPF2 ZIC2 ZNF121 ZFHX2 CTBP1 ZNF692 EGR1 CYTOR LINC01943 ENSG00000284879 LOC101928152
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CYTOR on UCSC Golden Path with GeneCards custom track

Genomic Locations for CYTOR Gene

Genomic Locations for CYTOR Gene
chr2:87,454,781-87,636,740
(GRCh38/hg38)
Size:
181,960 bases
Orientation:
Plus strand
chr2:87,754,887-87,906,324
(GRCh37/hg19)
Size:
151,438 bases
Orientation:
Plus strand

Genomic View for CYTOR Gene

Genes around CYTOR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CYTOR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CYTOR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CYTOR Gene

Proteins for CYTOR Gene

Post-translational modifications for CYTOR Gene

No Post-translational modifications

No data available for DME Specific Peptides for CYTOR Gene

Domains & Families for CYTOR Gene

Gene Families for CYTOR Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CYTOR: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CYTOR Gene

Function for CYTOR Gene

genes like me logo Genes that share phenotypes with CYTOR: view

Animal Model Products

miRNA for CYTOR Gene

miRTarBase miRNAs that target CYTOR

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CYTOR Gene

Localization for CYTOR Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CYTOR Gene

Pathways & Interactions for CYTOR Gene

SuperPathways for CYTOR Gene

No Data Available

Interacting Proteins for CYTOR Gene

Gene Ontology (GO) - Biological Process for CYTOR Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CYTOR Gene

Drugs & Compounds for CYTOR Gene

No Compound Related Data Available

Transcripts for CYTOR Gene

mRNA/cDNA for CYTOR Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CYTOR Gene

No ASD Table

Relevant External Links for CYTOR Gene

GeneLoc Exon Structure for
CYTOR
ECgene alternative splicing isoforms for
CYTOR

Expression for CYTOR Gene

NURSA nuclear receptor signaling pathways regulating expression of CYTOR Gene:

CYTOR
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CYTOR Gene

Orthologs for CYTOR Gene

Evolution for CYTOR Gene

ENSEMBL:
Gene Tree for CYTOR (if available)
TreeFam:
Gene Tree for CYTOR (if available)

No data available for Orthologs for CYTOR Gene

Paralogs for CYTOR Gene

No data available for Paralogs for CYTOR Gene

Variants for CYTOR Gene

Sequence variations from dbSNP and Humsavar for CYTOR Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000038248 -- 87,470,414(+) A/T intron_variant
rs1000070828 -- 87,470,656(+) C/T intron_variant
rs1000075244 -- 87,477,855(+) T/C intron_variant
rs1000123901 -- 87,476,211(+) A/G intron_variant
rs1000291165 -- 87,518,613(+) C/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CYTOR Gene

Variant ID Type Subtype PubMed ID
dgv33n64 CNV gain 17921354
dgv3887n100 CNV gain 25217958
dgv3888n100 CNV gain 25217958
dgv3889n100 CNV loss 25217958
dgv3891n100 CNV gain 25217958
dgv3892n100 CNV gain+loss 25217958
dgv3893n100 CNV gain 25217958
dgv3899n100 CNV loss 25217958
dgv3900n100 CNV gain 25217958
dgv3901n100 CNV gain+loss 25217958
dgv3903n100 CNV gain 25217958
dgv3904n100 CNV gain 25217958
dgv3905n100 CNV loss 25217958
dgv3906n100 CNV gain+loss 25217958
dgv3907n100 CNV gain 25217958
dgv3908n100 CNV gain 25217958
dgv3909n100 CNV loss 25217958
dgv3910n100 CNV gain 25217958
dgv3911n100 CNV gain+loss 25217958
dgv3912n100 CNV loss 25217958
dgv61n16 CNV deletion 17901297
dgv717e214 CNV gain 21293372
esv26476 CNV gain+loss 19812545
esv2759073 CNV gain+loss 17122850
esv2760646 CNV gain+loss 21179565
esv2763649 CNV gain+loss 21179565
esv33317 CNV gain 17666407
esv3591571 CNV loss 21293372
esv3892882 CNV gain 25118596
esv3892893 CNV gain 25118596
nsv1000885 CNV gain 25217958
nsv1001093 CNV gain 25217958
nsv1002910 CNV loss 25217958
nsv1003669 CNV loss 25217958
nsv1004454 CNV loss 25217958
nsv1004578 CNV loss 25217958
nsv10068 CNV gain+loss 18304495
nsv1008658 CNV loss 25217958
nsv1008957 CNV gain 25217958
nsv1011919 CNV loss 25217958
nsv1072005 CNV deletion 25765185
nsv1130752 CNV deletion 24896259
nsv1148611 CNV deletion 26484159
nsv1160815 CNV deletion 26073780
nsv1160816 CNV deletion 26073780
nsv2819 CNV deletion 18451855
nsv2820 CNV deletion 18451855
nsv428398 CNV loss 18775914
nsv442790 CNV loss 18776908
nsv514991 CNV gain 21397061
nsv516958 CNV gain+loss 19592680
nsv519198 CNV loss 19592680
nsv582374 CNV gain 21841781
nsv582375 CNV loss 21841781
nsv582378 CNV loss 21841781
nsv582379 CNV loss 21841781
nsv818068 CNV gain 17921354
nsv821626 CNV gain 15273396
nsv829491 CNV gain 20364138
nsv834284 CNV gain+loss 17160897
nsv834285 CNV gain 17160897
nsv955225 CNV deletion 24416366
nsv961432 CNV duplication 23825009

Additional Variant Information for CYTOR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CYTOR

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CYTOR Gene

Disorders for CYTOR Gene

MalaCards: The human disease database

(15) MalaCards diseases for CYTOR Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
clear cell renal cell carcinoma
  • clear cell carcinoma of kidney
gallbladder cancer
  • gallbladder ca
tongue squamous cell carcinoma
  • carcinoma, squamous cell
malignant glioma
squamous cell carcinoma, head and neck
  • hnscc
- elite association - COSMIC cancer census association via MalaCards
Search CYTOR in MalaCards View complete list of genes associated with diseases

Additional Disease Information for CYTOR

genes like me logo Genes that share disorders with CYTOR: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CYTOR Gene

Publications for CYTOR Gene

  1. Portraying breast cancers with long noncoding RNAs. (PMID: 27617288) Van Grembergen O … Fuks F (Science advances 2016) 2 3 58
  2. Long non-coding RNA Linc00152 is involved in cell cycle arrest, apoptosis, epithelial to mesenchymal transition, cell migration and invasion in gastric cancer. (PMID: 26237576) Zhao J … Huang G (Cell cycle (Georgetown, Tex.) 2015) 2 3 58
  3. Increased expression of long intergenic non-coding RNA LINC00152 in gastric cancer and its clinical significance. (PMID: 24523021) Pang Q … Guo J (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014) 2 3 58
  4. Identification of short-lived long non-coding RNAs as surrogate indicators for chemical stress response. (PMID: 24036268) Tani H … Torimura M (Biochemical and biophysical research communications 2013) 2 3 58
  5. LINC00152/miR-139-5p regulates gastric cancer cell aerobic glycolysis by targeting PRKAA1. (PMID: 29156518) Sun K … Xu F (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018) 3 58

Products for CYTOR Gene

Sources for CYTOR Gene

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