Aliases for CYTIP Gene
External Ids for CYTIP Gene
Previous HGNC Symbols for CYTIP Gene
Previous GeneCards Identifiers for CYTIP Gene
The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. The encoded protein modulates the activation of ARF genes by CYTH1. This protein interacts with CYTH1 and SNX27 proteins and may act to sequester CYTH1 protein in the cytoplasm.[provided by RefSeq, Aug 2008]
GeneCards Summary for CYTIP Gene
CYTIP (Cytohesin 1 Interacting Protein) is a Protein Coding gene. Among its related pathways are Amplification and Expansion of Oncogenic Pathways as Metastatic Traits. An important paralog of this gene is GRASP.
UniProtKB/Swiss-Prot for CYTIP Gene
By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.