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This gene encodes a member of the PSCD family of proteins, which have an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for as... See more...
Aliases for CYTH4 Gene
Aliases for CYTH4 Gene
External Ids for CYTH4 Gene
- HGNC: 9505
- Entrez Gene: 27128
- Ensembl: ENSG00000100055
- OMIM: 606514
- UniProtKB: Q9UIA0
Previous HGNC Symbols for CYTH4 Gene
- PSCD4
Previous GeneCards Identifiers for CYTH4 Gene
- GC22P036008
- GC22P037681
- GC22P020643
Summaries for CYTH4 Gene
-
This gene encodes a member of the PSCD family of proteins, which have an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family function as GEPs for ADP-ribosylation factors (ARFs), which are guanine nucleotide-binding proteins involved in vesicular trafficking pathways. This protein exhibits GEP activity in vitro with ARF1 and ARF5, but is inactive with ARF6. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
GeneCards Summary for CYTH4 Gene
CYTH4 (Cytohesin 4) is a Protein Coding gene. Diseases associated with CYTH4 include Septooptic Dysplasia. Among its related pathways are Intra-Golgi traffic and Pathogenic Escherichia coli infection. Gene Ontology (GO) annotations related to this gene include lipid binding and ARF guanyl-nucleotide exchange factor activity. An important paralog of this gene is CYTH3.
UniProtKB/Swiss-Prot Summary for CYTH4 Gene
-
Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.
Additional gene information for CYTH4 Gene
- HGNC(9505)
- Entrez Gene(27128)
- Ensembl(ENSG00000100055)
- OMIM(606514)
- UniProtKB(Q9UIA0)
- Open Targets Platform(ENSG00000100055)
- Monarch Initiative
- Search for CYTH4 at DataMed
- Search for CYTH4 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CYTH4 Gene
Genomics for CYTH4 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for CYTH4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CYTH4 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CYTH4
- Top Transcription factor binding sites by QIAGEN in the CYTH4 gene promoter:
-
- E47
- GR
- GR-alpha
- HEN1
- PPAR-gamma1
- PPAR-gamma2
- STAT3
- YY1
Genomic Locations for CYTH4 Gene
Genomic Locations for CYTH4 Gene
- chr22:37,282,027-37,315,341
- (GRCh38/hg38)
- Size:
- 33,315 bases
- Orientation:
- Plus strand
- chr22:37,678,068-37,711,389
- (GRCh37/hg19)
- Size:
- 33,322 bases
- Orientation:
- Plus strand
Genomic View for CYTH4 Gene
Genes around CYTH4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q13.1 by HGNC
- 22q13.1 by Entrez Gene
- 22q13.1 by Ensembl
CYTH4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CYTH4 Gene
Proteins for CYTH4 Gene
-
Protein details for CYTH4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UIA0-CYH4_HUMAN
- Recommended name:
- Cytohesin-4
- Protein Accession:
- Q9UIA0
- Q5R3F9
- Q9UGT6
Protein attributes for CYTH4 Gene
- Size:
- 394 amino acids
- Molecular mass:
- 45672 Da
- Quaternary structure:
- No Data Available
Protein Expression for CYTH4 Gene
Post-translational modifications for CYTH4 Gene
Other Protein References for CYTH4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-CYTH4 monoclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for CYTH4
- Novus Biologicals Antibodies for CYTH4
- Invitrogen Antibodies for CYTH4 (AFLGC-CYTH4)
-
Boster Bio Antibodies for CYTH4
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for CYTH4
- Origene Custom Protein Services for CYTH4
- antibodies-online: Show 7 available Cytohesin 4 Proteins ranked by validation data
- Compare Top Cytohesin 4 Proteins
-
Quality Products:
-
Abcam proteins for CYTH4
No data available for DME Specific Peptides for CYTH4 Gene
Domains & Families for CYTH4 Gene
Gene Families for CYTH4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for CYTH4 Gene
- InterPro:
- Blocks:
-
- Pleckstrin-like
- SEC7-like domain
- ProtoNet:
Suggested Antigen Peptide Sequences for CYTH4 Gene
- GenScript: Design optimal peptide antigens:
-
- Cytohesin 4 (B1AHH7_HUMAN)
- Cytohesin 4 (B1AHH8_HUMAN)
- Cytohesin 4 (B1AHI0_HUMAN)
- Cytohesin 4 (B1AHI1_HUMAN)
- PH, SEC7 and coiled-coil domain-containing protein 4 (CYH4_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9UIA0UniProtKB/Swiss-Prot:
CYH4_HUMAN :- Binds via its PH domain to the inositol head group of phosphatidylinositol 3,4,5-trisphosphate.
- Domain:
-
- Binds via its PH domain to the inositol head group of phosphatidylinositol 3,4,5-trisphosphate.
- Autoinhibited by its C-terminal basic region.
Function for CYTH4 Gene
Molecular function for CYTH4 Gene
- UniProtKB/Swiss-Prot Function:
- Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.
Phenotypes From GWAS Catalog for CYTH4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity | IEA | -- |
| GO:0005086 | ARF guanyl-nucleotide exchange factor activity | IEA,IDA | 10652308 |
| GO:0005515 | protein binding | IPI | 31515488 |
| GO:0008289 | lipid binding | IEA | -- |
Phenotypes for CYTH4 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CYTH4 - Select products 50% OFF >
- * CYTH4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for CYTH4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CYTH4
-
Santa Cruz Biotechnology (SCBT) CRISPR for CYTH4
miRNA for CYTH4 Gene
- miRTarBase miRNAs that target CYTH4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CYTH4
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Clone Products
- Applied Biological Materials (abm): Clones for CYTH4 - Select products 50% OFF >
- * CYTH4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for CYTH4
- Addgene plasmids for CYTH4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CYTH4
Cell Line Products
-
Horizon Cell Lines for CYTH4
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CYTH4 Gene
Localization for CYTH4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CYTH4 Gene
- Cell membrane. Peripheral membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytosol | 5 |
| golgi apparatus | 4 |
| mitochondrion | 2 |
| nucleus | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005886 | plasma membrane | IEA,IDA | 17398095 |
| GO:0016020 | membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CYTH4 Gene
Pathways & Interactions for CYTH4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Vesicle-mediated transport | ||
| 2 | Endocytosis | ||
| 3 | Pathogenic Escherichia coli infection | ||
| 4 | Phospholipase D signaling pathway | ||
| 5 | Salmonella infection (KEGG) | ||
Pathways by source for CYTH4 Gene
4 Reactome pathways for CYTH4 Gene
5 KEGG pathways for CYTH4 Gene
Interacting Proteins for CYTH4 Gene
Selected Interacting proteins:
Q9UIA0-CYH4_HUMAN
ENSP00000248901
for CYTH4 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for CYTH4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0032012 | regulation of ARF protein signal transduction | IEA | -- |
No data available for SIGNOR curated interactions for CYTH4 Gene
Drugs & Compounds for CYTH4 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Guanosine triphosphate | Experimental | Pharma | 0 |
Transcripts for CYTH4 Gene
mRNA/cDNA for CYTH4 Gene
- 2 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 11 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000457992 652 nts (view in UCSC)
- ENST00000248901 3077 nts (view in UCSC)
- ENST00000402997 633 nts (view in UCSC)
- ENST00000405206 636 nts (view in UCSC)
- ENST00000469886 1128 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CYTH4 - Select products 50% OFF >
- * CYTH4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for CYTH4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CYTH4
-
Santa Cruz Biotechnology (SCBT) CRISPR for CYTH4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CYTH4
- Browse OriGene Inhibitory RNA Products For CYTH4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CYTH4
Clone Products
- Applied Biological Materials (abm): Clones for CYTH4 - Select products 50% OFF >
- * CYTH4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for CYTH4
- Addgene plasmids for CYTH4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CYTH4
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - |
| ExUns: | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c |
|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||
| SP2: | - | ||||||||
| SP3: | |||||||||
| SP4: | |||||||||
| SP5: | |||||||||
| SP6: | |||||||||
| SP7: | |||||||||
| SP8: | |||||||||
| SP9: |
Relevant External Links for CYTH4 Gene
- GeneLoc Exon Structure for
- CYTH4
Expression for CYTH4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Plasmacytoid Dendritic cells Peripheral Blood
- Bone (Muscoskeletal System)
-
Thymus (Hematopoietic System)
mRNA differential expression in normal tissues according to GTEx for CYTH4 Gene
This gene is overexpressed in Whole Blood (x32.9) and Spleen (x4.2).
This gene is overexpressed in CD8 Tcells (17.3), Pancreas (9.9), Blymphocyte (9.2), Peripheral blood mononuclear cells (7.9), Monocytes (6.7), Spleen (6.3), and NK cells (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CYTH4 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CYTH4
SOURCE GeneReport for Unigene cluster for CYTH4 Gene:
Hs.170944mRNA Expression by UniProt/SwissProt for CYTH4 Gene:
Q9UIA0-CYH4_HUMAN
Tissue specificity:
Expressed predominantly in peripheral blood leukocytes.
Evidence on tissue expression from TISSUES for CYTH4 Gene
- Blood(4.6)
- Nervous system(4.4)
- Liver(4.1)
- Adrenal gland(2.6)
- Intestine(2)
Primer Products
-
OriGene qPCR primer pairs for CYTH4
-
OriGene qPCR primer pairs and template standards for CYTH4
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CYTH4 Gene
Orthologs for CYTH4 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | CYTH4 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | CYTH4 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | CYTH4 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Rat (Rattus norvegicus) |
Mammalia | Cyth4 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Cyth4 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | CYTH4 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | CYTH4 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | CYTH4 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | cyth4b 30 31 |
|
OneToMany | |
| cyth4a 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | step 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | grp-1 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SEC7 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.8851 31 |
|
ManyToMany | |
| -- 31 |
|
ManyToMany |
- Species where no ortholog for CYTH4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
Evolution for CYTH4 Gene
- ENSEMBL:
- Gene Tree for CYTH4 (if available)
- TreeFam:
- Gene Tree for CYTH4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CYTH4: view image
Paralogs for CYTH4 Gene
Paralogs for CYTH4 Gene
(8) SIMAP similar genes for CYTH4 Gene using alignment to 7 proteins:
- CYH4_HUMAN
- B1AHH4_HUMAN
- B1AHH5_HUMAN
- B1AHH6_HUMAN
- H0Y724_HUMAN
- L8E9K5_HUMAN
- Q8WWE8_HUMAN
Variants for CYTH4 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CYTH4 Gene
| SNP ID | Clinical significance and condition | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 734144 | Benign: not provided | 37,297,591(+) | C/T | SYNONYMOUS_VARIANT | |
| 734145 | Benign: not provided | 37,297,648(+) | A/C | MISSENSE_VARIANT | |
| 781618 | Benign: not provided | 37,296,051(+) | A/G | MISSENSE_VARIANT | |
| rs16998061 | - | p.Met74Val |
Residual Variation Intolerance Score:
16.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.47;
54.98% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CYTH4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CYTH4
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CYTH4 Gene
Disorders for CYTH4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| septooptic dysplasia |
|
|
Search CYTH4 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CYTH4
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for CYTH4 Gene
Publications for CYTH4 Gene
- The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane. (PMID: 17398095) Hofmann I … Munro S (Current biology : CB 2007) 3 4 23
- Similarities in function and gene structure of cytohesin-4 and cytohesin-1, guanine nucleotide-exchange proteins for ADP-ribosylation factors. (PMID: 10652308) Ogasawara M … Vaughan M (The Journal of biological chemistry 2000) 3 4 23
- The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I … O'Brien KP (Nature 1999) 2 3 4
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for CYTH4 Gene
- Custom Antibody ServicesOriGene Antibodies for CYTH4
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- Custom Assay Services
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- Origene Custom Protein Services for CYTH4
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- Browse OriGene Inhibitory RNA Products For CYTH4
- OriGene qPCR primer pairs for CYTH4
- OriGene qPCR primer pairs and template standards for CYTH4
- OriGene CRISPR knockouts for CYTH4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CYTH4
- Sino Biological Human cDNA Clone for CYTH4
- Browse Sino Biological Recombinant Proteins
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- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for CYTH4
- Novus Biologicals proteins and lysates for CYTH4
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam proteins for CYTH4
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for CYTH4 (AFLGC-CYTH4)
- VectorBuilder Custom and pre-made DNA vectors for CYTH4 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for CYTH4 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for CYTH4 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for CYTH4 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for CYTH4
- Addgene plasmids for CYTH4
- antibodies-online: Show 16 available Cytohesin 4 Antibodies ranked by validation data
- Compare Top Cytohesin 4 Antibodies
- antibodies-online: Search results for available Cytohesin 4 related products ranked by validation data
- antibodies-online: Show 7 available Cytohesin 4 Proteins ranked by validation data
- Compare Top Cytohesin 4 Proteins
- Quality Products:
- Horizon Cell Lines for CYTH4
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CYTH4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CYTH4
- Search GeneCopoeia for miRNA 3'UTR Target clone products for CYTH4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CYTH4
- Boster Bio Antibodies for CYTH4
- Browse Boster Bio ELISA Kits
Sources for CYTH4 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
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