Aliases for CYTH4 Gene
Aliases for CYTH4 Gene
External Ids for CYTH4 Gene
- HGNC: 9505
- Entrez Gene: 27128
- Ensembl: ENSG00000100055
- OMIM: 606514
- UniProtKB: Q9UIA0
Previous HGNC Symbols for CYTH4 Gene
- PSCD4
Previous GeneCards Identifiers for CYTH4 Gene
- GC22P036008
- GC22P037681
- GC22P020643
Summaries for CYTH4 Gene
-
This gene encodes a member of the PSCD family of proteins, which have an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family function as GEPs for ADP-ribosylation factors (ARFs), which are guanine nucleotide-binding proteins involved in vesicular trafficking pathways. This protein exhibits GEP activity in vitro with ARF1 and ARF5, but is inactive with ARF6. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
GeneCards Summary for CYTH4 Gene
CYTH4 (Cytohesin 4) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and Phospholipase D signaling pathway. Gene Ontology (GO) annotations related to this gene include lipid binding and ARF guanyl-nucleotide exchange factor activity. An important paralog of this gene is CYTH3.
UniProtKB/Swiss-Prot for CYTH4 Gene
-
Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.
Additional gene information for CYTH4 Gene
- Monarch Initiative
- Search for CYTH4 at DataMed
- Search for CYTH4 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYTH4 Gene
Genomics for CYTH4 Gene
GeneHancer (GH) Regulatory Elements for CYTH4 Gene
Promoters and enhancers for CYTH4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CYTH4 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the CYTH4 gene promoter:
Regulatory Element Products
Genomic Locations for CYTH4 Gene
Genomic Locations for CYTH4 Gene
- chr22:37,282,027-37,315,348
- (GRCh38/hg38)
- Size:
- 33,322 bases
- Orientation:
- Plus strand
- chr22:37,678,068-37,711,389
- (GRCh37/hg19)
Genomic View for CYTH4 Gene
Genes around CYTH4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q13.1 by Entrez Gene
- 22q13.1 by HGNC
- 22q13.1 by Ensembl
CYTH4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CYTH4 Gene
Proteins for CYTH4 Gene
-
Protein details for CYTH4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UIA0-CYH4_HUMAN
- Recommended name:
- Cytohesin-4
- Protein Accession:
- Q9UIA0
- Q5R3F9
- Q9UGT6
Protein attributes for CYTH4 Gene
- Size:
- 394 amino acids
- Molecular mass:
- 45672 Da
- Quaternary structure:
- No Data Available
Protein Expression for CYTH4 Gene
Post-translational modifications for CYTH4 Gene
Other Protein References for CYTH4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CYTH4
- Novus Biologicals Antibodies for CYTH4
- Invitrogen Antibodies for CYTH4
- GeneTex CYTH4 Antibody for CYTH4
Protein Products
-
OriGene Purified Proteins for CYTH4
- Search Origene for MassSpec and Protein Over-expression Lysates for CYTH4
- Origene Custom Protein Services for CYTH4
- Search GeneTex for Proteins for CYTH4
Assay Products
No data available for DME Specific Peptides for CYTH4 Gene
Domains & Families for CYTH4 Gene
Gene Families for CYTH4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for CYTH4 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CYTH4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UIA0UniProtKB/Swiss-Prot:
CYH4_HUMAN :- Binds via its PH domain to the inositol head group of phosphatidylinositol 3,4,5-trisphosphate.
- Domain:
-
- Binds via its PH domain to the inositol head group of phosphatidylinositol 3,4,5-trisphosphate.
- Autoinhibited by its C-terminal basic region.
Function for CYTH4 Gene
Molecular function for CYTH4 Gene
- UniProtKB/Swiss-Prot Function:
- Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.
Phenotypes From GWAS Catalog for CYTH4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity | IEA | -- |
| GO:0005086 | ARF guanyl-nucleotide exchange factor activity | IDA,IEA | 10652308 |
| GO:0008289 | lipid binding | IEA | -- |
Phenotypes for CYTH4 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CYTH4
-
CRISPR Products
-
OriGene CRISPR knockouts for CYTH4
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- genomics-online: gRNA clones - Search results for 99 available Cytohesin 4 gene related products
- Overview of 99 available Cytohesin 4 gene related products
- Applied Biological Materials CRISPR for CYTH4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CYTH4
- GenScript: Design CRISPR guide RNA sequences for CYTH4
miRNA for CYTH4 Gene
- miRTarBase miRNAs that target CYTH4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CYTH4
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- genomics-online: shRNA clones - Search results for 99 available Cytohesin 4 gene related products
- Overview of 99 available Cytohesin 4 gene related products
Clone Products
- Sino Biological Human cDNA Clone for CYTH4
- VectorBuilder custom plasmid, inducible vectors for CYTH4
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CYTH4
- Applied Biological Materials Clones for CYTH4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for CYTH4
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CYTH4 Gene
Localization for CYTH4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CYTH4 Gene
- Cell membrane; Peripheral membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytosol | 5 |
| golgi apparatus | 4 |
| mitochondrion | 2 |
| nucleus | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005886 | plasma membrane | IDA,IEA | 17398095 |
| GO:0016020 | membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CYTH4 Gene
Pathways & Interactions for CYTH4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Vesicle-mediated transport | ||
| 2 | Endocytosis | ||
| 3 | Phospholipase D signaling pathway | ||
| 4 | Golgi-to-ER retrograde transport | ||
| 5 | Intra-Golgi traffic | ||
Pathways by source for CYTH4 Gene
4 Reactome pathways for CYTH4 Gene
2 KEGG pathways for CYTH4 Gene
Interacting Proteins for CYTH4 Gene
Selected Interacting proteins:
Q9UIA0-CYH4_HUMAN
ENSP00000248901
for CYTH4 Gene via
IID
UniProtKB
STRING
GPS-Prot Interaction Network for CYTH4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0032012 | regulation of ARF protein signal transduction | IEA | -- |
| GO:0065009 | regulation of molecular function | IEA | -- |
No data available for SIGNOR curated interactions for CYTH4 Gene
Drugs & Compounds for CYTH4 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Guanosine triphosphate | Experimental | Pharma | 0 |
Transcripts for CYTH4 Gene
mRNA/cDNA for CYTH4 Gene
- (129) Selected AceView cDNA sequences:
- (10) Additional mRNA sequences :
- (4) REFSEQ mRNAs :
- (11) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000248901 3206 bps (uc003arf.4)
- ENST00000402997 633 bps (uc062dwz.1)
- ENST00000405206 636 bps (uc062dxa.1)
- ENST00000439667 725 bps (uc062dxe.1)
- ENST00000446506 569 bps (uc062dxh.1)
CRISPR Products
-
OriGene CRISPR knockouts for CYTH4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CYTH4
- genomics-online: gRNA clones - Search results for 99 available Cytohesin 4 gene related products
- Overview of 99 available Cytohesin 4 gene related products
- Applied Biological Materials CRISPR for CYTH4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CYTH4
- GenScript: Design CRISPR guide RNA sequences for CYTH4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CYTH4
- Browse OriGene Inhibitory RNA Products For CYTH4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CYTH4
- genomics-online: shRNA clones - Search results for 99 available Cytohesin 4 gene related products
- Overview of 99 available Cytohesin 4 gene related products
Clone Products
- Sino Biological Human cDNA Clone for CYTH4
- VectorBuilder custom plasmid, inducible vectors for CYTH4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CYTH4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CYTH4
- Applied Biological Materials Clones for CYTH4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - |
| ExUns: | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c |
|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||
| SP2: | - | ||||||||
| SP3: | |||||||||
| SP4: | |||||||||
| SP5: | |||||||||
| SP6: | |||||||||
| SP7: | |||||||||
| SP8: | |||||||||
| SP9: |
Expression for CYTH4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Plasmacytoid Dendritic cells Peripheral Blood
- Bone (Muscoskeletal System)
-
Thymus (Hematopoietic System)
mRNA differential expression in normal tissues according to GTEx for CYTH4 Gene
This gene is overexpressed in Whole Blood (x32.9) and Spleen (x4.2).
This gene is overexpressed in CD8 Tcells (17.3), Pancreas (9.9), Blymphocyte (9.2), Peripheral blood mononuclear cells (7.9), Monocytes (6.7), Spleen (6.3), and NK cells (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CYTH4 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CYTH4 Gene:
CYTH4SOURCE GeneReport for Unigene cluster for CYTH4 Gene:
Hs.170944mRNA Expression by UniProt/SwissProt for CYTH4 Gene:
Q9UIA0-CYH4_HUMAN
Tissue specificity:
Expressed predominantly in peripheral blood leukocytes.
Evidence on tissue expression from TISSUES for CYTH4 Gene
- Blood(4.5)
- Nervous system(4.4)
- Liver(4.1)
- Adrenal gland(2.6)
Primer Products
-
OriGene qPCR primer pairs and template standards for CYTH4
-
OriGene qPCR primer pairs for CYTH4
- genomics-online: primer clones - Search results for 99 available Cytohesin 4 gene related products
- Overview of 99 available Cytohesin 4 gene related products
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CYTH4 Gene
Orthologs for CYTH4 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CYTH4 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | CYTH4 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | CYTH4 34 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| rat (Rattus norvegicus) |
Mammalia | Cyth4 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Cyth4 16 34 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CYTH4 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CYTH4 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | CYTH4 34 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | cyth4b 34 33 |
|
OneToMany | |
| cyth4a 34 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | step 34 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | grp-1 34 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SEC7 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.8851 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany |
- Species where no ortholog for CYTH4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Evolution for CYTH4 Gene
- ENSEMBL:
- Gene Tree for CYTH4 (if available)
- TreeFam:
- Gene Tree for CYTH4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CYTH4: view image
Paralogs for CYTH4 Gene
Paralogs for CYTH4 Gene
(8) SIMAP similar genes for CYTH4 Gene using alignment to 7 proteins:
- CYH4_HUMAN
- B1AHH4_HUMAN
- B1AHH5_HUMAN
- B1AHH6_HUMAN
- H0Y724_HUMAN
- L8E9K5_HUMAN
- Q8WWE8_HUMAN
Variants for CYTH4 Gene
| SNP ID | Clin | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000099098 | -- | 37,280,948(+) | A/G | upstream_transcript_variant | |
| rs1000163646 | -- | 37,311,794(+) | A/G | downstream_transcript_variant, genic_downstream_transcript_variant, intron_variant | |
| rs1000265954 | -- | 37,306,969(+) | G/A | intron_variant | |
| rs1000313886 | -- | 37,295,196(+) | C/A | intron_variant | |
| rs1000326184 | -- | 37,281,001(+) | G/A | upstream_transcript_variant |
Residual Variation Intolerance Score:
16.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.47;
54.98% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CYTH4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CYTH4
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CYTH4 Gene
Disorders for CYTH4 Gene
Additional Disease Information for CYTH4
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for CYTH4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CYTH4 Gene
Publications for CYTH4 Gene
- The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane. (PMID: 17398095) Hofmann I … Munro S (Current biology : CB 2007) 3 4 22 58
- Similarities in function and gene structure of cytohesin-4 and cytohesin-1, guanine nucleotide-exchange proteins for ADP-ribosylation factors. (PMID: 10652308) Ogasawara M … Vaughan M (The Journal of biological chemistry 2000) 3 4 22 58
- The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I … O'Brien KP (Nature 1999) 2 3 4 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
Products for CYTH4 Gene
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- VectorBuilder custom plasmid, inducible vectors for CYTH4
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 61 available Cytohesin 4 Antibodies ranked by validation data
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- antibodies-online: Search results for available Cytohesin 4 related products ranked by validation data
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- Compare Top Cytohesin 4 Proteins
- GeneTex CYTH4 Antibody for CYTH4
- Search GeneTex for Proteins for CYTH4
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- genomics-online: cdna clones - Search results for 99 available Cytohesin 4 gene related products
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Sources for CYTH4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
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- (13) InterPro
- (14) ProtoNet
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- (16) MGI
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- (21) IntAct
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- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
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- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
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- (52) HUGE
- (53) IMGT
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- (55) miRBase
- (56) DME
- (57) OriGene
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- (60) TGDB
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- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
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- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
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- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
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- (145) dbSUPER
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- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
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- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
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- (168) Boster Bio