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Aliases for CYP4Z2P Gene

Aliases for CYP4Z2P Gene

  • Cytochrome P450 Family 4 Subfamily Z Member 2, Pseudogene 2 3 5
  • Cytochrome P450, Family 4, Subfamily Z, Polypeptide 2, Pseudogene 2 3
  • Cytochrome P450 4Z2 Pseudogene 3

External Ids for CYP4Z2P Gene

Previous GeneCards Identifiers for CYP4Z2P Gene

  • GC01M046695
  • GC01M046678
  • GC01M046693
  • GC01M047035
  • GC01M047309
  • GC01M045439

Summaries for CYP4Z2P Gene

GeneCards Summary for CYP4Z2P Gene

CYP4Z2P (Cytochrome P450 Family 4 Subfamily Z Member 2, Pseudogene) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen.

Additional gene information for CYP4Z2P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYP4Z2P Gene

Genomics for CYP4Z2P Gene

GeneHancer (GH) Regulatory Elements for CYP4Z2P Gene

Promoters and enhancers for CYP4Z2P Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J046903 Enhancer 0.6 ENCODE 0.7 -3.2 -3249 0.2 SMARCE1 ZNF687 FOXA2 DPF2 MNT FOXA1 SP1 ZNF217 CTBP1 CREB1 CYP4Z2P GC01P046925
GH01J046857 Enhancer 0.5 Ensembl 0.3 +42.6 42647 0.6 ATF1 MTA1 PHF20 GABPB1 LOC100533627 CYP4Z2P GC01M046749
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CYP4Z2P on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CYP4Z2P gene promoter:
  • LHX3b
  • Lhx3a
  • Pax-5
  • Gfi-1
  • AML1a
  • RORalpha1
  • Arnt
  • E47
  • Tal-1beta

Genomic Locations for CYP4Z2P Gene

Genomic Locations for CYP4Z2P Gene
57,381 bases
Minus strand
57,381 bases
Minus strand

Genomic View for CYP4Z2P Gene

Genes around CYP4Z2P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CYP4Z2P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CYP4Z2P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CYP4Z2P Gene

Proteins for CYP4Z2P Gene

  • Protein details for CYP4Z2P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative inactive cytochrome P450 family member 4Z2
    Protein Accession:
    Secondary Accessions:
    • Q66ZJ5

    Protein attributes for CYP4Z2P Gene

    340 amino acids
    Molecular mass:
    40159 Da
    Name=heme; Xref=ChEBI:CHEBI:30413;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CYP4Z2P Gene


neXtProt entry for CYP4Z2P Gene

Post-translational modifications for CYP4Z2P Gene

No Post-translational modifications

No data available for DME Specific Peptides for CYP4Z2P Gene

Domains & Families for CYP4Z2P Gene

Gene Families for CYP4Z2P Gene

Protein Domains for CYP4Z2P Gene


Suggested Antigen Peptide Sequences for CYP4Z2P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the cytochrome P450 family.
  • Belongs to the cytochrome P450 family.
genes like me logo Genes that share domains with CYP4Z2P: view

Function for CYP4Z2P Gene

Phenotypes From GWAS Catalog for CYP4Z2P Gene

Gene Ontology (GO) - Molecular Function for CYP4Z2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005506 iron ion binding IEA --
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA --
GO:0020037 heme binding IEA --
genes like me logo Genes that share ontologies with CYP4Z2P: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CYP4Z2P Gene

Localization for CYP4Z2P Gene

Subcellular locations from UniProtKB/Swiss-Prot for CYP4Z2P Gene

Membrane; Single-pass type II membrane protein.

Gene Ontology (GO) - Cellular Components for CYP4Z2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CYP4Z2P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for CYP4Z2P Gene

Pathways & Interactions for CYP4Z2P Gene

SuperPathways for CYP4Z2P Gene

No Data Available

Interacting Proteins for CYP4Z2P Gene

Selected Interacting proteins: Q8N1L4-CP4Z2_HUMAN for CYP4Z2P Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for CYP4Z2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with CYP4Z2P: view

No data available for Pathways by source and SIGNOR curated interactions for CYP4Z2P Gene

Drugs & Compounds for CYP4Z2P Gene

No Compound Related Data Available

Transcripts for CYP4Z2P Gene

mRNA/cDNA for CYP4Z2P Gene

(2) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CYP4Z2P Gene

Cytochrome P450, family 4, subfamily Z, polypeptide 2 pseudogene:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CYP4Z2P Gene

No ASD Table

Relevant External Links for CYP4Z2P Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CYP4Z2P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CYP4Z2P Gene

mRNA differential expression in normal tissues according to GTEx for CYP4Z2P Gene

This gene is overexpressed in Breast - Mammary Tissue (x16.1).

NURSA nuclear receptor signaling pathways regulating expression of CYP4Z2P Gene:


SOURCE GeneReport for Unigene cluster for CYP4Z2P Gene:


mRNA Expression by UniProt/SwissProt for CYP4Z2P Gene:

Tissue specificity: Detected at low levels in mammary gland and mammary carcinoma.
genes like me logo Genes that share expression patterns with CYP4Z2P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CYP4Z2P Gene

Orthologs for CYP4Z2P Gene

Evolution for CYP4Z2P Gene

Gene Tree for CYP4Z2P (if available)
Gene Tree for CYP4Z2P (if available)

No data available for Orthologs for CYP4Z2P Gene

Paralogs for CYP4Z2P Gene

(13) SIMAP similar genes for CYP4Z2P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CYP4Z2P: view

No data available for Paralogs for CYP4Z2P Gene

Variants for CYP4Z2P Gene

Sequence variations from dbSNP and Humsavar for CYP4Z2P Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000049269 -- 46,900,827(-) C/T upstream_transcript_variant
rs1000106740 -- 46,852,885(-) A/G intron_variant
rs1000118682 -- 46,846,511(-) G/A/C intron_variant
rs1000137628 -- 46,890,231(-) T/C intron_variant
rs1000200991 -- 46,873,645(-) C/ intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CYP4Z2P Gene

Variant ID Type Subtype PubMed ID
dgv160n100 CNV gain 25217958
esv2670875 CNV deletion 23128226
esv2763300 CNV gain 21179565
esv3585938 CNV gain 21293372
esv3585941 CNV loss 21293372
esv3585942 CNV loss 21293372
esv3585943 CNV gain 21293372
nsv1009338 CNV gain 25217958
nsv525401 CNV loss 19592680
nsv945927 CNV duplication 23825009

Additional Variant Information for CYP4Z2P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CYP4Z2P Gene

Disorders for CYP4Z2P Gene

Additional Disease Information for CYP4Z2P

No disorders were found for CYP4Z2P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CYP4Z2P Gene

Publications for CYP4Z2P Gene

  1. Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma. (PMID: 15059886) Rieger MA … Weigle B (Cancer research 2004) 2 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. The competing endogenous RNA network of CYP4Z1 and pseudogene CYP4Z2P exerts an anti-apoptotic function in breast cancer. (PMID: 28236635) Li C … Xi T (FEBS letters 2017) 3 58
  4. The 3'UTR of the pseudogene CYP4Z2P promotes tumor angiogenesis in breast cancer by acting as a ceRNA for CYP4Z1. (PMID: 25701119) Zheng L … Xi T (Breast cancer research and treatment 2015) 3 58
  5. An atlas of genetic influences on human blood metabolites. (PMID: 24816252) Shin SY … Soranzo N (Nature genetics 2014) 3 58

Products for CYP4Z2P Gene

Sources for CYP4Z2P Gene

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