Aliases for CYP2U1 Gene
Aliases for CYP2U1 Gene
External Ids for CYP2U1 Gene
- HGNC: 20582
- Entrez Gene: 113612
- Ensembl: ENSG00000155016
- OMIM: 610670
- UniProtKB: Q7Z449
Previous GeneCards Identifiers for CYP2U1 Gene
- GC04P109309
- GC04P109210
- GC04P109072
- GC04P108852
- GC04P104584
Summaries for CYP2U1 Gene
-
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. [provided by RefSeq, Jul 2008]
GeneCards Summary for CYP2U1 Gene
CYP2U1 (Cytochrome P450 Family 2 Subfamily U Member 1) is a Protein Coding gene. Diseases associated with CYP2U1 include Spastic Paraplegia 56, Autosomal Recessive and Spastic Paraplegia 46, Autosomal Recessive. Among its related pathways are Cytochrome P450 - arranged by substrate type and acetone degradation I (to methylglyoxal). Gene Ontology (GO) annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. An important paralog of this gene is CYP2D6.
UniProtKB/Swiss-Prot for CYP2U1 Gene
-
Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes.
Additional gene information for CYP2U1 Gene
- Monarch Initiative
- Search for CYP2U1 at DataMed
- Search for CYP2U1 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYP2U1 Gene
Genomics for CYP2U1 Gene
GeneHancer (GH) Regulatory Elements for CYP2U1 Gene
Promoters and enhancers for CYP2U1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around CYP2U1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the CYP2U1 gene promoter:
-
- HSF2
- YY1
- AREB6
- GATA-1
- AML1a
- POU2F1
- POU2F1a
- AP-4
- POU6F1 (c2)
- HNF-3beta
Regulatory Element Products
Genomic Locations for CYP2U1 Gene
Genomic Locations for CYP2U1 Gene
- chr4:107,931,369-107,953,461
- (GRCh38/hg38)
- Size:
- 22,093 bases
- Orientation:
- Plus strand
- chr4:108,852,525-108,874,613
- (GRCh37/hg19)
- Size:
- 22,089 bases
- Orientation:
- Plus strand
Genomic View for CYP2U1 Gene
Genes around CYP2U1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4q25 by Entrez Gene
- 4q25 by HGNC
- 4q25 by Ensembl
CYP2U1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CYP2U1 Gene
Proteins for CYP2U1 Gene
-
Protein details for CYP2U1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q7Z449-CP2U1_HUMAN
- Recommended name:
- Cytochrome P450 2U1
- Protein Accession:
- Q7Z449
- B2RMV7
- Q96EQ6
Protein attributes for CYP2U1 Gene
- Size:
- 544 amino acids
- Molecular mass:
- 61987 Da
- Cofactor:
- Name=heme; Xref=ChEBI:CHEBI:30413;
- Quaternary structure:
- No Data Available
Protein Expression for CYP2U1 Gene
Post-translational modifications for CYP2U1 Gene
Other Protein References for CYP2U1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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-
Abcam antibodies for CYP2U1
- Invitrogen Antibodies for CYP2U1 (AFLGC-CYP2U1)
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-
Santa Cruz Biotechnology (SCBT) Antibodies for CYP2U1
Protein Products
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- antibodies-online: Search results for 3 available CYP2U1 Proteins ranked by validation data
- Compare Top CYP2U1 Proteins
-
Quality Products:
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-
Abcam proteins for CYP2U1
Assay Products
- antibodies-online: Search results for 2 available CYP2U1 Elisa Kits ranked by validation data
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-
Quality Products:
No data available for DME Specific Peptides for CYP2U1 Gene
Domains & Families for CYP2U1 Gene
Gene Families for CYP2U1 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Disease related genes
- Enzymes
- Potential drug targets
- Predicted membrane proteins
Protein Domains for CYP2U1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CYP2U1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q7Z449- Family:
-
- Belongs to the cytochrome P450 family.
Function for CYP2U1 Gene
Molecular function for CYP2U1 Gene
- UniProtKB/Swiss-Prot Function:
- Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes.
- UniProtKB/Swiss-Prot CatalyticActivity:
- RH + [reduced NADPH--hemoprotein reductase] + O(2) = ROH + [oxidized NADPH--hemoprotein reductase] + H(2)O.
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=2.7 uM for arachidonic acid;
Enzyme Numbers (IUBMB) for CYP2U1 Gene
Phenotypes From GWAS Catalog for CYP2U1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004497 | monooxygenase activity | TAS | -- |
| GO:0005506 | iron ion binding | IEA | -- |
| GO:0008395 | steroid hydroxylase activity | IBA | -- |
| GO:0016491 | oxidoreductase activity | IEA | -- |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEA | -- |
Phenotypes for CYP2U1 Gene
- MGI mutant phenotypes for CYP2U1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CYP2U1:
Animal Models for CYP2U1 Gene
- MGI Knock Outs for CYP2U1:
-
- Cyp2u1 Cyp2u1<tm1b(EUCOMM)Wtsi>
Animal Model Products
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-
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-
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-
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miRNA for CYP2U1 Gene
- miRTarBase miRNAs that target CYP2U1
-
- hsa-mir-375 (MIRT019811)
- hsa-mir-155-5p (MIRT020782)
- hsa-mir-124-3p (MIRT022645)
- hsa-mir-19b-3p (MIRT031184)
- hsa-mir-19a-3p (MIRT092954)
- hsa-mir-497-3p (MIRT092955)
- hsa-mir-1468-3p (MIRT092957)
- hsa-mir-548f-5p (MIRT092958)
- hsa-mir-548g-5p (MIRT092959)
- hsa-mir-548x-5p (MIRT092960)
- hsa-mir-548aj-5p (MIRT092962)
- hsa-mir-548aw (MIRT092964)
- hsa-mir-192-3p (MIRT211016)
- hsa-mir-4711-3p (MIRT558493)
- hsa-mir-3662 (MIRT567867)
- hsa-mir-510-3p (MIRT647209)
- hsa-mir-7152-5p (MIRT647210)
- hsa-mir-3074-5p (MIRT647211)
- hsa-mir-488-3p (MIRT647212)
- hsa-mir-1200 (MIRT647213)
- hsa-mir-378a-5p (MIRT647214)
- hsa-mir-3124-3p (MIRT647215)
- hsa-mir-501-5p (MIRT647216)
- hsa-mir-500a-5p (MIRT647217)
miRNA Products
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Clone Products
- Sino Biological Human cDNA Clone for CYP2U1
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- Applied Biological Materials Clones for CYP2U1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for CYP2U1
No data available for Transcription Factor Targets and HOMER Transcription for CYP2U1 Gene
Localization for CYP2U1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CYP2U1 Gene
- Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| plasma membrane | 3 |
| mitochondrion | 1 |
- Golgi apparatus (2)
- Vesicles (2)
- Nucleoplasm (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IBA | -- |
| GO:0005783 | endoplasmic reticulum | IEA | -- |
| GO:0005789 | endoplasmic reticulum membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for CYP2U1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cytochrome P450 - arranged by substrate type | ||
| 2 | Metabolism |
.37
|
|
| 3 | superpathway of tryptophan utilization | ||
| 4 | Arachidonic acid metabolism | ||
| 5 | nicotine degradation IV | ||
Pathways by source for CYP2U1 Gene
9 BioSystems pathways for CYP2U1 Gene
8 Reactome pathways for CYP2U1 Gene
2 KEGG pathways for CYP2U1 Gene
Interacting Proteins for CYP2U1 Gene
GPS-Prot Interaction Network for CYP2U1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006082 | organic acid metabolic process | IBA | -- |
| GO:0006805 | xenobiotic metabolic process | IBA | -- |
| GO:0042738 | exogenous drug catabolic process | IBA | -- |
| GO:0055114 | oxidation-reduction process | IEA | -- |
| GO:0097267 | omega-hydroxylase P450 pathway | TAS | -- |
No data available for SIGNOR curated interactions for CYP2U1 Gene
Transcripts for CYP2U1 Gene
mRNA/cDNA for CYP2U1 Gene
- (3) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (106) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000332884 4944 bps (uc003hyp.4)
- ENST00000513302 1562 bps (uc062ywd.1)
- ENST00000508453 3125 bps (uc011cfi.3)
Unigene Clusters for CYP2U1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CYP2U1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CYP2U1
- genomics-online: gRNA clones - Search results for available CYP2U1 gene related products
- Applied Biological Materials CRISPR for CYP2U1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CYP2U1
- GenScript: Design CRISPR guide RNA sequences for CYP2U1
miRNA Products
Inhibitory RNA Products
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Clone Products
- Sino Biological Human cDNA Clone for CYP2U1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CYP2U1
- genomics-online: cdna clones - Search results for available CYP2U1 gene related products
- orf clones - Search results for available CYP2U1 gene related products
- Applied Biological Materials Clones for CYP2U1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for CYP2U1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Thymus (Hematopoietic System)
- Double Positive Thymocytes Thymus
-
Blood (Cardiovascular System)
- Double Positive Thymocytes Thymus
This gene is overexpressed in Urinary Bladder (52.9) and Gallbladder (12.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CYP2U1 Gene
NURSA nuclear receptor signaling pathways regulating expression of CYP2U1 Gene:
CYP2U1SOURCE GeneReport for Unigene cluster for CYP2U1 Gene:
Hs.109087mRNA Expression by UniProt/SwissProt for CYP2U1 Gene:
Q7Z449-CP2U1_HUMAN
Tissue specificity:
Widely expressed with stronger expression in thymus, heart and cerebellum.
Evidence on tissue expression from TISSUES for CYP2U1 Gene
- Nervous system(4.6)
Phenotype-based relationships between genes and organs from Gene ORGANizer for CYP2U1 Gene
Germ Layers:
- ectoderm
- mesoderm
Systems:
- nervous
- skeletal muscle
- skeleton
Regions:
Head and neck:
- brain
- cerebellum
- head
Limb:
- digit
- foot
- lower limb
- toe
General:
- peripheral nerve
- peripheral nervous system
Primer Products
-
OriGene qPCR primer pairs for CYP2U1
- genomics-online: primer clones - Search results for available CYP2U1 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues for CYP2U1 Gene
Orthologs for CYP2U1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CYP2U1 34 |
|
OneToOne | |
| LOC471267 33 |
|
||||
| dog (Canis familiaris) |
Mammalia | CYP2U1 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | CYP2U1 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Cyp2u1 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Cyp2u1 16 34 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CYP2U1 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | CYP2U1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | LOC422528 33 |
|
||
| CYP2U1 34 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | CYP2U1 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cyp2u1 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | cyp2u1 34 33 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | Cyp18a1 33 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT5G04330 33 |
|
- Species where no ortholog for CYP2U1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for CYP2U1 Gene
- ENSEMBL:
- Gene Tree for CYP2U1 (if available)
- TreeFam:
- Gene Tree for CYP2U1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CYP2U1: view image
Paralogs for CYP2U1 Gene
(32) SIMAP similar genes for CYP2U1 Gene using alignment to 2 proteins:
- CP2U1_HUMAN
- E9PGH5_HUMAN
Variants for CYP2U1 Gene
| SNP ID | Clin | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs141431913 | pathogenic, Spastic paraplegia 56, autosomal recessive, Spastic paraplegia 56, autosomal recessive (SPG56) [MIM:615030] | 107,950,250(+) | C/T | coding_sequence_variant, missense_variant | |
| rs142676629 | benign, Spastic paraplegia | 107,947,400(+) | G/T | coding_sequence_variant, missense_variant | |
| rs147506864 | uncertain-significance, Spastic paraplegia | 107,931,951(+) | C/T | coding_sequence_variant, missense_variant | |
| rs147612190 | benign, Spastic paraplegia | 107,932,139(+) | C/G/T | coding_sequence_variant, intron_variant, missense_variant | |
| rs148983337 | benign, Spastic paraplegia | 107,945,471(+) | A/G | coding_sequence_variant, intron_variant, missense_variant |
Residual Variation Intolerance Score:
47.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.46;
28.55% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CYP2U1 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CYP2U1 Gene
Disorders for CYP2U1 Gene
(9) MalaCards diseases for CYP2U1 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| spastic paraplegia 56, autosomal recessive |
|
|
| spastic paraplegia 46, autosomal recessive |
|
|
| spastic paraplegia 54, autosomal recessive |
|
|
| spastic paraplegia 35, autosomal recessive |
|
|
| charcot-marie-tooth disease, axonal, type 2t |
|
|
Search CYP2U1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
CP2U1_HUMAN- Spastic paraplegia 56, autosomal recessive (SPG56) [MIM:615030]: A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. Complicated forms are recognized by additional variable features including spastic quadriparesis, seizures, dementia, amyotrophy, extrapyramidal disturbance, cerebral or cerebellar atrophy, optic atrophy, and peripheral neuropathy, as well as by extra neurological manifestations. In SPG56, upper limbs are often also affected. Some SPG56 patients may have a subclinical axonal neuropathy. {ECO:0000269 PubMed:23176821}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for CYP2U1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for CYP2U1 Gene
Publications for CYP2U1 Gene
- CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids. (PMID: 14660610) Chuang SS … Korczak B (The Journal of biological chemistry 2004) 2 3 4 22 58
- Characterization and tissue distribution of a novel human cytochrome P450-CYP2U1. (PMID: 14975754) Karlgren M … Ingelman-Sundberg M (Biochemical and biophysical research communications 2004) 2 3 4 58
- A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts. (PMID: 20332099) Kalsi G … Riley BP (Human molecular genetics 2010) 3 44 58
- Membrane-bound human orphan cytochrome P450 2U1: Sequence singularities, construction of a full 3D model, and substrate docking. (PMID: 28743672) Ducassou L … André F (Biochimie 2017) 3 58
- Cytochrome P450 2U1, a very peculiar member of the human P450s family. (PMID: 28083596) Dhers L … Mansuy D (Cellular and molecular life sciences : CMLS 2017) 3 58
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- genomics-online: cdna clones - Search results for available CYP2U1 gene related products
- orf clones - Search results for available CYP2U1 gene related products
- genomics-online: gRNA clones - Search results for available CYP2U1 gene related products
- genomics-online: primer clones - Search results for available CYP2U1 gene related products
- genomics-online: shRNA clones - Search results for available CYP2U1 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CYP2U1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CYP2U1
- GeneCopoeia miRNA 3'UTR Target clone products for CYP2U1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CYP2U1
Sources for CYP2U1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt