Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CYP2G1P Gene

Aliases for CYP2G1P Gene

  • Cytochrome P450 Family 2 Subfamily G Member 1, Pseudogene 2 3 5
  • Cytochrome P450, Family 2, Subfamily G, Polypeptide 1 Pseudogene 2 3
  • CYP2GP1 3 4
  • Cytochrome P450, Subfamily IIG, Polypeptide 1, Pseudogene 3
  • Cytochrome P450, Subfamily IIG, Olfactory-Specific 3
  • Cytochrome P450 2G1 Pseudogene 4
  • CYP2G2P 3
  • CYP2G1 3

External Ids for CYP2G1P Gene

Previous HGNC Symbols for CYP2G1P Gene

  • CYP2G1

Previous GeneCards Identifiers for CYP2G1P Gene

  • GC19P046089
  • GC19P041396

Summaries for CYP2G1P Gene

GeneCards Summary for CYP2G1P Gene

CYP2G1P (Cytochrome P450 Family 2 Subfamily G Member 1, Pseudogene) is a Pseudogene. Among its related pathways are Cytochrome P450 - arranged by substrate type and nicotine degradation IV. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen.

Additional gene information for CYP2G1P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYP2G1P Gene

Genomics for CYP2G1P Gene

GeneHancer (GH) Regulatory Elements for CYP2G1P Gene

Promoters and enhancers for CYP2G1P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J040347 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 40.6 -542.2 -542242 2.2 CLOCK MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 PLD3 C19orf47 ZNF780B SNRPA HNRNPUL1 ENSG00000269843 ZNF780A CYP2G1P SUPT5H NUMBL
GH19J040796 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 29.2 -88.5 -88489 11.8 CLOCK MLX ZFP64 FEZF1 DMAP1 YY1 ZNF213 ZNF416 ZNF143 SP3 EGLN2 ENSG00000268797 ZNF780B SNRPA HNRNPUL1 CCDC97 ENSG00000269843 NUMBL ZNF546 COQ8B
GH19J040596 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 29.1 -289.1 -289130 10 CLOCK MLX FEZF1 DMAP1 YY1 ZNF213 E2F8 ZNF416 ZNF143 ZNF548 LTBP4 HNRNPUL1 SNRPA ENSG00000269843 ZNF780B CCDC97 ZNF780A AKT2 FBL COQ8B
GH19J040089 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 23 -800.3 -800298 2.4 MLX ZFP64 FEZF1 DMAP1 YY1 ZNF213 E2F8 ZNF416 ZNF143 ZNF548 ZNF780A ENSG00000269749 ENSG00000269296 SNRPA ENSG00000269843 FBL PLEKHG2 ITPKC SUPT5H CYP2G1P
GH19J041348 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 23 +460.8 460787 6.9 HDGF PKNOX1 ZFP64 ARID4B SIN3A YBX1 DMAP1 IRF4 YY1 ZNF213 TMEM91 ENSG00000255730 TGFB1 ZNF526 SNRPA ZNF574 HNRNPUL1 CCDC97 ENSG00000269843 COQ8B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CYP2G1P on UCSC Golden Path with GeneCards custom track

Genomic Locations for CYP2G1P Gene

Genomic Locations for CYP2G1P Gene
chr19:40,890,826-40,900,508
(GRCh38/hg38)
Size:
9,683 bases
Orientation:
Plus strand
chr19:41,396,731-41,406,413
(GRCh37/hg19)
Size:
9,683 bases
Orientation:
Plus strand

Genomic View for CYP2G1P Gene

Genes around CYP2G1P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CYP2G1P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CYP2G1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CYP2G1P Gene

Proteins for CYP2G1P Gene

  • Protein details for CYP2G1P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZSU1-C2G1P_HUMAN
    Recommended name:
    Putative inactive cytochrome P450 2G1
    Protein Accession:
    Q6ZSU1

    Protein attributes for CYP2G1P Gene

    Size:
    146 amino acids
    Molecular mass:
    16683 Da
    Cofactor:
    Name=heme; Xref=ChEBI:CHEBI:30413;
    Quaternary structure:
    No Data Available

neXtProt entry for CYP2G1P Gene

Post-translational modifications for CYP2G1P Gene

No Post-translational modifications

No data available for DME Specific Peptides for CYP2G1P Gene

Domains & Families for CYP2G1P Gene

Gene Families for CYP2G1P Gene

Protein Domains for CYP2G1P Gene

Suggested Antigen Peptide Sequences for CYP2G1P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZSU1

UniProtKB/Swiss-Prot:

C2G1P_HUMAN :
  • Belongs to the cytochrome P450 family.
Family:
  • Belongs to the cytochrome P450 family.
genes like me logo Genes that share domains with CYP2G1P: view

Function for CYP2G1P Gene

Phenotypes From GWAS Catalog for CYP2G1P Gene

Gene Ontology (GO) - Molecular Function for CYP2G1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005506 iron ion binding IEA --
GO:0008392 arachidonic acid epoxygenase activity IBA --
GO:0008395 steroid hydroxylase activity IBA --
GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IBA --
GO:0020037 heme binding IEA --
genes like me logo Genes that share ontologies with CYP2G1P: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CYP2G1P Gene

Localization for CYP2G1P Gene

Gene Ontology (GO) - Cellular Components for CYP2G1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA --
GO:0043231 intracellular membrane-bounded organelle IBA --
genes like me logo Genes that share ontologies with CYP2G1P: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for CYP2G1P Gene

Pathways & Interactions for CYP2G1P Gene

genes like me logo Genes that share pathways with CYP2G1P: view

Pathways by source for CYP2G1P Gene

Interacting Proteins for CYP2G1P Gene

Gene Ontology (GO) - Biological Process for CYP2G1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006082 organic acid metabolic process IBA --
GO:0006805 xenobiotic metabolic process IBA --
GO:0019373 epoxygenase P450 pathway IBA --
GO:0042738 exogenous drug catabolic process IBA --
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with CYP2G1P: view

No data available for SIGNOR curated interactions for CYP2G1P Gene

Drugs & Compounds for CYP2G1P Gene

No Compound Related Data Available

Transcripts for CYP2G1P Gene

mRNA/cDNA for CYP2G1P Gene

(2) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CYP2G1P Gene

Cytochrome P450, family 2, subfamily G, polypeptide 1 pseudogene:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CYP2G1P Gene

No ASD Table

Relevant External Links for CYP2G1P Gene

GeneLoc Exon Structure for
CYP2G1P
ECgene alternative splicing isoforms for
CYP2G1P

Expression for CYP2G1P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CYP2G1P Gene

mRNA differential expression in normal tissues according to GTEx for CYP2G1P Gene

This gene is overexpressed in Breast - Mammary Tissue (x4.5).

NURSA nuclear receptor signaling pathways regulating expression of CYP2G1P Gene:

CYP2G1P

SOURCE GeneReport for Unigene cluster for CYP2G1P Gene:

Hs.738699
genes like me logo Genes that share expression patterns with CYP2G1P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CYP2G1P Gene

Orthologs for CYP2G1P Gene

Evolution for CYP2G1P Gene

ENSEMBL:
Gene Tree for CYP2G1P (if available)
TreeFam:
Gene Tree for CYP2G1P (if available)

No data available for Orthologs for CYP2G1P Gene

Paralogs for CYP2G1P Gene

(23) SIMAP similar genes for CYP2G1P Gene using alignment to 2 proteins:

  • C2G1P_HUMAN
  • Q16411_HUMAN
genes like me logo Genes that share paralogs with CYP2G1P: view

No data available for Paralogs for CYP2G1P Gene

Variants for CYP2G1P Gene

Sequence variations from dbSNP and Humsavar for CYP2G1P Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000124646 -- 40,894,422(+) T/C intron_variant
rs1000157221 -- 40,894,734(+) G/A intron_variant
rs1000323152 -- 40,900,693(+) C/A downstream_transcript_variant
rs1000493962 -- 40,896,138(+) G/C intron_variant
rs1000673624 -- 40,900,392(+) T/C non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CYP2G1P Gene

Variant ID Type Subtype PubMed ID
nsv960838 CNV duplication 23825009
nsv1125310 OTHER inversion 24896259
nsv1066637 CNV gain 25217958
nsv1065886 CNV loss 25217958
nsv1056244 CNV gain 25217958
esv33053 CNV gain 17666407
esv2758762 CNV gain+loss 17122850
esv2718571 CNV deletion 23290073
esv2718569 CNV deletion 23290073
dgv3540n100 CNV gain 25217958
dgv3539n100 CNV loss 25217958
dgv1783n106 CNV deletion 24896259

Additional Variant Information for CYP2G1P Gene

Human Gene Mutation Database (HGMD)
CYP2G1P
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CYP2G1P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CYP2G1P Gene

Disorders for CYP2G1P Gene

Additional Disease Information for CYP2G1P

No disorders were found for CYP2G1P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CYP2G1P Gene

Publications for CYP2G1P Gene

  1. Characterization of human CYP2G genes: widespread loss-of-function mutations and genetic polymorphism. (PMID: 11186129) Sheng J … Ding X (Pharmacogenetics 2000) 2 3 4 22 58
  2. Identification of human genes related to olfactory-specific CYP2G1. (PMID: 8561797) Sheng J … Ding X (Biochemical and biophysical research communications 1996) 2 3 22 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  4. Comparative genomics search for losses of long-established genes on the human lineage. (PMID: 18085818) Zhu J … Haussler D (PLoS computational biology 2007) 3 58
  5. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. (PMID: 15128046) Nelson DR … Nebert DW (Pharmacogenetics 2004) 3 58

Products for CYP2G1P Gene

Sources for CYP2G1P Gene

Content
Loading form....