Aliases for CYGB Gene
External Ids for CYGB Gene
Previous GeneCards Identifiers for CYGB Gene
This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012]
GeneCards Summary for CYGB Gene
CYGB (Cytoglobin) is a Protein Coding gene. Diseases associated with CYGB include Retinitis Pigmentosa 36 and Esophageal Diverticulosis. Among its related pathways are eNOS activation and regulation and Metabolism. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxygen binding. An important paralog of this gene is HBZ.
UniProtKB/Swiss-Prot Summary for CYGB Gene
May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.