CYBA Gene (Protein Coding)

Cytochrome B-245 Alpha Chain

GC16M088643
GIFtS:
47
Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to... See more...

Aliases for CYBA Gene

Aliases for CYBA Gene

  • Cytochrome B-245 Alpha Chain 2 3 5
  • Superoxide-Generating NADPH Oxidase Light Chain Subunit 3 4
  • Neutrophil Cytochrome B 22 KDa Polypeptide 3 4
  • Flavocytochrome B-558 Alpha Polypeptide 2 3
  • Cytochrome B-245, Alpha Polypeptide 2 3
  • Cytochrome B(558) Alpha Chain 3 4
  • Cytochrome B558 Subunit Alpha 3 4
  • Cytochrome B-245 Light Chain 3 4
  • P22 Phagocyte B-Cytochrome 3 4
  • P22-PHOX 2 3
  • P22phox 3 4
  • Cytochrome B(558) Alpha-Subunit 3
  • Cytochrome B, Alpha Polypeptide 3
  • Cytochrome B Light Chain 3
  • P22-Phox 4
  • CYBA 5

External Ids for CYBA Gene

Previous GeneCards Identifiers for CYBA Gene

  • GC16M080145
  • GC16M089678
  • GC16M088413
  • GC16M088453
  • GC16M087237
  • GC16M088709
  • GC16M074403

Summaries for CYBA Gene

Entrez Gene Summary for CYBA Gene

  • Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells. [provided by RefSeq, Jul 2008]

GeneCards Summary for CYBA Gene

CYBA (Cytochrome B-245 Alpha Chain) is a Protein Coding gene. Diseases associated with CYBA include Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Negative and Chronic Granulomatous Disease. Among its related pathways are Signaling by GPCR and RHO GTPases Activate NADPH Oxidases. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and SH3 domain binding.

UniProtKB/Swiss-Prot Summary for CYBA Gene

  • Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Gene Wiki entry for CYBA Gene

Additional gene information for CYBA Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CYBA Gene

Genomics for CYBA Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for CYBA Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CYBA on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CYBA

Top Transcription factor binding sites by QIAGEN in the CYBA gene promoter:
  • AP-1
  • p53
  • PPAR-gamma2
  • Sp1

Genomic Locations for CYBA Gene

Genomic Locations for CYBA Gene
chr16:88,643,289-88,651,079
(GRCh38/hg38)
Size:
7,791 bases
Orientation:
Minus strand
chr16:88,709,691-88,717,560
(GRCh37/hg19)
Size:
7,870 bases
Orientation:
Minus strand

Genomic View for CYBA Gene

Genes around CYBA on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CYBA Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CYBA Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for CYBA Gene

Proteins for CYBA Gene

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  • Protein details for CYBA Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P13498-CY24A_HUMAN
    Recommended name:
    Cytochrome b-245 light chain
    Protein Accession:
    P13498
    Secondary Accessions:
    • Q14090
    • Q9BR72

    Protein attributes for CYBA Gene

    Size:
    195 amino acids
    Molecular mass:
    21013 Da
    Quaternary structure:
    • Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain). Interacts with SH3PXD2A (By similarity). Interacts with DUOX1, DUOX2 and TPO. Interacts with NOX3 and NOX4. Interacts with calprotectin (S100A8/9).

    Three dimensional structures from OCA and Proteopedia for CYBA Gene

neXtProt entry for CYBA Gene

Protein Expression for CYBA Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for CYBA Gene

  • The heme prosthetic group could be coordinated with residues of the light chain, the heavy chain, or both, and it is possible that more than one heme is present per cytochrome b-245.
  • Phosphorylation at Thr-147 enhances NADPH oxidase activity by promoting p47phox binding.
  • Ubiquitinated at Lys-149 likely by RNF145.
  • Ubiquitination at Lys149
  • Modification sites at PhosphoSitePlus

Other Protein References for CYBA Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CYBA Gene

Domains & Families for CYBA Gene

Gene Families for CYBA Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Potential drug targets
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Transporters

Protein Domains for CYBA Gene

InterPro:
Blocks:
  • Cytochrome b558 alpha-subunit
ProtoNet:

Suggested Antigen Peptide Sequences for CYBA Gene

GenScript: Design optimal peptide antigens:
  • p22-phox (CY24A_HUMAN)
  • Flavocytochrome b-558 alpha polypeptide (Q86SL0_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P13498

UniProtKB/Swiss-Prot:

CY24A_HUMAN :
  • Belongs to the p22phox family.
Family:
  • Belongs to the p22phox family.
genes like me logo Genes that share domains with CYBA: view

Function for CYBA Gene

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Molecular function for CYBA Gene

UniProtKB/Swiss-Prot Function:
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
GENATLAS Biochemistry:
cytochrome b-558,alpha polypeptide,(22kDa,membrane bound component of the NADPH oxidase system,cypb245),p22-phox,mainly expressed in neutrophiles,oxygen dependent mechanism of phagocytosis

Phenotypes From GWAS Catalog for CYBA Gene

Gene Ontology (GO) - Molecular Function for CYBA Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 3305576
GO:0009055 electron transfer activity IDA,TAS 2243141
GO:0016175 contributes_to superoxide-generating NADPH oxidase activity IEA,IMP 1763037
GO:0016491 oxidoreductase activity IEA --
GO:0017124 SH3 domain binding IPI 7938008
genes like me logo Genes that share ontologies with CYBA: view
genes like me logo Genes that share phenotypes with CYBA: view

Human Phenotype Ontology for CYBA Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for CYBA Gene

MGI Knock Outs for CYBA:
  • Cyba Cyba<tm1a(EUCOMM)Wtsi>

Animal Model Products

CRISPR Products

miRNA for CYBA Gene

miRTarBase miRNAs that target CYBA

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CYBA

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for CYBA Gene

Localization for CYBA Gene

Subcellular locations from UniProtKB/Swiss-Prot for CYBA Gene

Cell membrane. Note=As unassembled monomer may localize to the endoplasmic reticulum. {ECO:0000250 UniProtKB:Q61462}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CYBA gene
Compartment Confidence
plasma membrane 5
endoplasmic reticulum 4
cytoskeleton 3
mitochondrion 3
nucleus 3
endosome 3
cytosol 3
golgi apparatus 3
extracellular 2
peroxisome 2
lysosome 2

Gene Ontology (GO) - Cellular Components for CYBA Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001725 stress fiber IEA --
GO:0005623 cell IEA --
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
GO:0005768 endosome IEA --
genes like me logo Genes that share ontologies with CYBA: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for CYBA Gene

Pathways & Interactions for CYBA Gene

genes like me logo Genes that share pathways with CYBA: view

Pathways by source for CYBA Gene

4 GeneGo (Thomson Reuters) pathways for CYBA Gene
  • G-protein signaling RAC1 in cellular process
  • G-protein signaling_Rac2 regulation pathway
  • Immune response CCR3 signaling in eosinophils
  • Inhibitory action of Lipoxins on Superoxide production in neutrophils
1 Qiagen pathway for CYBA Gene
  • Transendothelial Migration of Leukocytes

SIGNOR curated interactions for CYBA Gene

Is activated by:

Gene Ontology (GO) - Biological Process for CYBA Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001666 response to hypoxia IEA --
GO:0001938 positive regulation of endothelial cell proliferation IEA --
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent TAS --
GO:0003106 negative regulation of glomerular filtration by angiotensin IEA --
GO:0006801 superoxide metabolic process IEA,IMP 1763037
genes like me logo Genes that share ontologies with CYBA: view

Drugs & Compounds for CYBA Gene

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(20) Drugs for CYBA Gene - From: DrugBank, PharmGKB, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Dextromethorphan Approved Pharma Target, inhibitor 166
Doxorubicin Approved, Investigational Pharma Topo II inhibitor,immunosuppresive antineoplastic antibiotic 2029
Idarubicin Approved Pharma 258
Simvastatin Approved Pharma Inhibitor, Competitive HMG-CoA reductase inhibitor 582
NADPH Experimental Pharma 0

(12) Additional Compounds for CYBA Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with CYBA: view

Transcripts for CYBA Gene

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  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for CYBA Gene

1 REFSEQ mRNAs :
11 NCBI additional mRNA sequence :
10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CYBA

Alternative Splicing Database (ASD) splice patterns (SP) for CYBA Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8
SP1: - - - - - -
SP2: - - - - -
SP3: - - - -
SP4: - -
SP5: - -
SP6:

Relevant External Links for CYBA Gene

GeneLoc Exon Structure for
CYBA

Expression for CYBA Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CYBA Gene

mRNA expression in normal human tissues for CYBA Gene
mRNA expression by BioGPS for CYBA GenemRNA expression by GTEx for CYBA Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CYBA Gene

This gene is overexpressed in Whole Blood (x19.7) and Spleen (x5.6).

Protein differential expression in normal tissues from HIPED for CYBA Gene

This gene is overexpressed in Nasal epithelium (24.0), Neutrophil (16.5), and Monocytes (10.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CYBA Gene



Protein tissue co-expression partners for CYBA Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CYBA

SOURCE GeneReport for Unigene cluster for CYBA Gene:

Hs.513803

Evidence on tissue expression from TISSUES for CYBA Gene

  • Nervous system(4.6)
  • Blood(3.6)
  • Intestine(3.6)
  • Kidney(3.3)
  • Pancreas(3.3)
  • Heart(3.3)
  • Bone marrow(3.2)
  • Spleen(3.2)
  • Muscle(3.1)
  • Lymph node(3.1)
  • Lung(3)
  • Liver(2.8)
  • Stomach(2.8)
  • Skin(2.6)
  • Adrenal gland(2.4)
  • Thyroid gland(2.3)

Phenotype-based relationships between genes and organs from Gene ORGANizer for CYBA Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • digestive
  • immune
  • integumentary
  • lymphatic
  • nervous
  • respiratory
  • skeleton
  • urinary
Regions:
Head and neck:
  • brain
  • cheek
  • ear
  • eye
  • face
  • head
  • jaw
  • lacrimal apparatus
  • lip
  • mandible
  • maxilla
  • meninges
  • middle ear
  • mouth
  • neck
  • scalp
  • sinus
  • skull
Thorax:
  • bronchus
  • chest wall
  • clavicle
  • esophagus
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
  • trachea
Abdomen:
  • intestine
  • kidney
  • large intestine
  • liver
  • small intestine
  • spleen
  • stomach
Pelvis:
  • anus
  • pelvis
  • rectum
  • ureter
  • urethra
  • urinary bladder
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • blood
  • bone marrow
  • lymph node
  • skin
  • spinal column
  • vertebrae
  • white blood cell
genes like me logo Genes that share expression patterns with CYBA: view

No data available for mRNA Expression by UniProt/SwissProt for CYBA Gene

Orthologs for CYBA Gene

This gene was present in the common ancestor of chordates.

Orthologs for CYBA Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia CYBA 30 31
  • 98.8 (n)
 OneToOne
Cow
(Bos Taurus)
 Mammalia CYBA 30 31
  • 85.51 (n)
 OneToOne
Rat
(Rattus norvegicus)
 Mammalia Cyba 30
  • 84.2 (n)
Dog
(Canis familiaris)
 Mammalia CYBA 30 31
  • 83.42 (n)
 OneToOne
Mouse
(Mus musculus)
 Mammalia Cyba 30 17 31
  • 82.81 (n)
 OneToOne
Platypus
(Ornithorhynchus anatinus)
 Mammalia CYBA 31
  • 75 (a)
 OneToOne
Oppossum
(Monodelphis domestica)
 Mammalia CYBA 31
  • 74 (a)
 OneToOne
Chicken
(Gallus gallus)
 Aves CYBA 31
  • 77 (a)
 OneToOne
Lizard
(Anolis carolinensis)
 Reptilia CYBA 31
  • 75 (a)
 OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
 Amphibia cyba 30
  • 64.88 (n)
Str.15394 30
African clawed frog
(Xenopus laevis)
 Amphibia Xl.5967 30
Zebrafish
(Danio rerio)
 Actinopterygii cyba 30 31
  • 58.67 (n)
 OneToOne
zgc66077 30
Rainbow Trout
(Oncorhynchus mykiss)
 Actinopterygii Omy.8225 30
Sea Squirt
(Ciona savignyi)
 Ascidiacea -- 31
  • 37 (a)
 OneToOne
Species where no ortholog for CYBA was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for CYBA Gene

ENSEMBL:
Gene Tree for CYBA (if available)
TreeFam:
Gene Tree for CYBA (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CYBA: view image

Paralogs for CYBA Gene

No data available for Paralogs for CYBA Gene

Variants for CYBA Gene

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  1. SNP Genotyping and Copy Number Assay

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CYBA Gene

SNP ID Clinical significance and condition Chr 16 pos Variation AA Info Type
636575 Pathogenic: not provided 88,646,781(-) G/C NONSENSE
638954 Uncertain Significance: Granulomatous disease, chronic, autosomal recessive, cytochrome b-negative 88,643,466(-) G/A MISSENSE_VARIANT
642309 Uncertain Significance: Granulomatous disease, chronic, autosomal recessive, cytochrome b-negative 88,643,414(-) G/A MISSENSE_VARIANT
643066 Uncertain Significance: Granulomatous disease, chronic, autosomal recessive, cytochrome b-negative 88,650,948(-) GCACT/G SPLICE_DONOR_VARIANT
645632 Uncertain Significance: Granulomatous disease, chronic, autosomal recessive, cytochrome b-negative 88,647,105(-) G/A MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for CYBA Gene

Structural Variations from Database of Genomic Variants (DGV) for CYBA Gene

Variant ID Type Subtype PubMed ID
esv3639554 CNV loss 21293372
nsv1113832 CNV deletion 24896259
nsv1926 CNV insertion 18451855
nsv471113 CNV loss 18288195
nsv482951 CNV loss 15286789
nsv833325 CNV loss 17160897
nsv952070 CNV deletion 24416366

Variation tolerance for CYBA Gene

Gene Damage Index Score: 4.16; 61.63% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CYBA Gene

Human Gene Mutation Database (HGMD)
CYBA
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CYBA

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CYBA Gene

Disorders for CYBA Gene

MalaCards: The human disease database

(18) MalaCards diseases for CYBA Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
granulomatous disease, chronic, autosomal recessive, cytochrome b-negative
  • cgd, autosomal recessive cytochrome b-negative
chronic granulomatous disease
  • granulomatous disease, chronic, x-linked
granulomatous disease, chronic, autosomal dominant type
  • autosomal dominant chronic granulomatous disease
diabetic polyneuropathy
  • diabetes mellitus with polyneuropathy
granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type i
  • cdg1
- elite association - COSMIC cancer census association via MalaCards
Search CYBA in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

CY24A_HUMAN
  • Granulomatous disease, chronic, cytochrome-b-negative, autosomal recessive (ARCGD) [MIM:233690]: A disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections. {ECO:0000269 PubMed:10759707, ECO:0000269 PubMed:10910929, ECO:0000269 PubMed:10914676, ECO:0000269 PubMed:1415254, ECO:0000269 PubMed:1763037, ECO:0000269 PubMed:18422995, ECO:0000269 PubMed:2243141, ECO:0000269 PubMed:23910690, ECO:0000269 PubMed:7964505, ECO:0000269 PubMed:8168815}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Genatlas disease for CYBA Gene

chronic granulomatous disease,autosomal (cypb558 deficiency)

Additional Disease Information for CYBA

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with CYBA: view

Publications for CYBA Gene

  1. Three common polymorphisms in the CYBA gene form a haplotype associated with decreased ROS generation. (PMID: 19388116) Bedard K … Krause KH (Human mutation 2009) 3 4 23 41
  2. Association of p22phox gene C242T polymorphism with coronary artery disease: a meta-analysis. (PMID: 20100625) Fang S … Jia C (Thrombosis research 2010) 3 23 41
  3. Haplotype analysis of the NADPH oxidase p22 phox gene in patients with bronchial asthma. (PMID: 18716406) Izakovicova Holla L … Znojil V (International archives of allergy and immunology 2009) 3 23 41
  4. Exercise training, NADPH oxidase p22phox gene polymorphisms, and hypertension. (PMID: 19516159) Feairheller DL … Fenty-Stewart NM (Medicine and science in sports and exercise 2009) 3 23 41
  5. Relationship between reduced nicotinamide adenine dinucleotide phosphate oxidase subunit p22phox gene polymorphism and obstructive sleep apnea-hypopnea syndrome in the Chinese Han population. (PMID: 19567155) Liu HG … Xu YJ (Chinese medical journal 2009) 3 23 41

ExternalLinks

View latest publications for CYBA gene in Mastermind

Products for CYBA Gene

  • Signalway ELISA kits for CYBA

Sources for CYBA Gene