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Aliases for CXorf67 Gene

Aliases for CXorf67 Gene

  • Chromosome X Open Reading Frame 67 2 3 5
  • Uncharacterized Protein CXorf67 3

External Ids for CXorf67 Gene

Previous GeneCards Identifiers for CXorf67 Gene

  • GC0XP051167
  • GC0XP048591
  • GC0XP051149

Summaries for CXorf67 Gene

GeneCards Summary for CXorf67 Gene

CXorf67 (Chromosome X Open Reading Frame 67) is a Protein Coding gene. Diseases associated with CXorf67 include Endometrial Stromal Sarcoma and Endometrial Stromal Nodule.

Additional gene information for CXorf67 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf67 Gene

Genomics for CXorf67 Gene

GeneHancer (GH) Regulatory Elements for CXorf67 Gene

Promoters and enhancers for CXorf67 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ051456 Enhancer 0.4 ENCODE 12.9 +49.7 49716 0.7 CTCF ZNF654 RAD21 NUDT11 CXorf67 LOC100419238
GH0XJ051495 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE 0.2 +89.3 89286 2.4 MXI1 USF1 ZIC2 ZNF335 GLIS2 POLR2A PATZ1 SCRT2 L3MBTL2 NRF1 NUDT11 CXorf67
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CXorf67 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CXorf67 gene promoter:
  • RSRFC4
  • Gfi-1
  • HEN1
  • GCNF-2
  • GCNF-1
  • GCNF
  • FOXL1
  • SEF-1 (1)
  • NF-YC
  • NF-YB

Genomic Locations for CXorf67 Gene

Genomic Locations for CXorf67 Gene
1,929 bases
Plus strand
1,924 bases
Plus strand

Genomic View for CXorf67 Gene

Genes around CXorf67 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CXorf67 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CXorf67 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CXorf67 Gene

Proteins for CXorf67 Gene

  • Protein details for CXorf67 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein CXorf67
    Protein Accession:

    Protein attributes for CXorf67 Gene

    503 amino acids
    Molecular mass:
    51894 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CXorf67 Gene

Post-translational modifications for CXorf67 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CXorf67 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Boster Bio Antibodies for CXorf67

No data available for DME Specific Peptides for CXorf67 Gene

Domains & Families for CXorf67 Gene

Gene Families for CXorf67 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CXorf67 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CXorf67: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CXorf67 Gene

Function for CXorf67 Gene

Phenotypes From GWAS Catalog for CXorf67 Gene

genes like me logo Genes that share phenotypes with CXorf67: view

Animal Model Products

miRNA for CXorf67 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CXorf67 Gene

Localization for CXorf67 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CXorf67 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for CXorf67 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with CXorf67: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CXorf67 Gene

Pathways & Interactions for CXorf67 Gene

SuperPathways for CXorf67 Gene

No Data Available

Interacting Proteins for CXorf67 Gene

Gene Ontology (GO) - Biological Process for CXorf67 Gene


No data available for Pathways by source and SIGNOR curated interactions for CXorf67 Gene

Drugs & Compounds for CXorf67 Gene

No Compound Related Data Available

Transcripts for CXorf67 Gene

mRNA/cDNA for CXorf67 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(8) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CXorf67 Gene

Chromosome X open reading frame 67:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CXorf67 Gene

No ASD Table

Relevant External Links for CXorf67 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CXorf67 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CXorf67 Gene

mRNA differential expression in normal tissues according to GTEx for CXorf67 Gene

This gene is overexpressed in Testis (x17.7) and Brain - Cerebellar Hemisphere (x4.3).

Protein differential expression in normal tissues from HIPED for CXorf67 Gene

This gene is overexpressed in Fetal ovary (28.4), Lung (24.2), and Testis (9.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CXorf67 Gene

Protein tissue co-expression partners for CXorf67 Gene

NURSA nuclear receptor signaling pathways regulating expression of CXorf67 Gene:


SOURCE GeneReport for Unigene cluster for CXorf67 Gene:


Evidence on tissue expression from TISSUES for CXorf67 Gene

  • Skin(4.1)
genes like me logo Genes that share expression patterns with CXorf67: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CXorf67 Gene

Orthologs for CXorf67 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CXorf67 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CXorf67 34
  • 84 (a)
(Canis familiaris)
Mammalia CXorf67 34
  • 42 (a)
Species where no ortholog for CXorf67 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CXorf67 Gene

Gene Tree for CXorf67 (if available)
Gene Tree for CXorf67 (if available)

Paralogs for CXorf67 Gene Pseudogenes for CXorf67 Gene

genes like me logo Genes that share paralogs with CXorf67: view

No data available for Paralogs for CXorf67 Gene

Variants for CXorf67 Gene

Sequence variations from dbSNP and Humsavar for CXorf67 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1002342784 -- 51,406,932(+) C/T 5_prime_UTR_variant
rs1002745842 -- 51,406,680(+) T/C upstream_transcript_variant
rs1005187482 -- 51,405,932(+) T/C upstream_transcript_variant
rs1005239939 -- 51,406,560(+) C/T upstream_transcript_variant
rs1006910285 -- 51,407,903(+) C/T coding_sequence_variant, missense_variant

Variation tolerance for CXorf67 Gene

Gene Damage Index Score: 0.42; 9.27% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CXorf67 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CXorf67 Gene

Disorders for CXorf67 Gene

MalaCards: The human disease database

(2) MalaCards diseases for CXorf67 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
endometrial stromal sarcoma
  • endometrial stromal sarcoma, high grade
endometrial stromal nodule
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for CXorf67

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with CXorf67: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CXorf67 Gene

Publications for CXorf67 Gene

  1. Identification of a novel, recurrent MBTD1-CXorf67 fusion in low-grade endometrial stromal sarcoma. (PMID: 23959973) Dewaele B … Debiec-Rychter M (International journal of cancer 2014) 2 3 58
  2. Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation. (PMID: 20564319) Kim ST … Sun J (The Prostate 2010) 3 44 58
  3. Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. (PMID: 18264098) Gudmundsson J … Stefansson K (Nature genetics 2008) 3 44 58
  4. A draft map of the human proteome. (PMID: 24870542) Kim MS … Pandey A (Nature 2014) 3 58
  5. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H … Mohammed S (Journal of proteome research 2013) 4 58

Products for CXorf67 Gene

Sources for CXorf67 Gene

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