Aliases for CXCR5 Gene
- C-X-C Motif Chemokine Receptor 5 2 3 5
- MDR15 2 3 4
- Burkitt Lymphoma Receptor 1, GTP Binding Protein (Chemokine (C-X-C Motif) Receptor 5) 2 3
- Burkitt Lymphoma Receptor 1, GTP-Binding Protein 2 3
- Chemokine (C-X-C Motif) Receptor 5 2 3
- C-X-C Chemokine Receptor Type 5 3 4
- Monocyte-Derived Receptor 15 3 4
External Ids for CXCR5 Gene
Previous HGNC Symbols for CXCR5 Gene
Previous GeneCards Identifiers for CXCR5 Gene
This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
GeneCards Summary for CXCR5 Gene
CXCR5 (C-X-C Motif Chemokine Receptor 5) is a Protein Coding gene. Diseases associated with CXCR5 include Intraocular Lymphoma and Lymphoma. Among its related pathways are Peptide ligand-binding receptors and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and C-X-C chemokine receptor activity. An important paralog of this gene is CXCR3.
UniProtKB/Swiss-Prot Summary for CXCR5 Gene
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.