Aliases for CXCL16 Gene
External Ids for CXCL16 Gene
Previous GeneCards Identifiers for CXCL16 Gene
GeneCards Summary for CXCL16 Gene
CXCL16 (C-X-C Motif Chemokine Ligand 16) is a Protein Coding gene. Diseases associated with CXCL16 include Xanthogranulomatous Cholecystitis. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include chemokine activity and low-density lipoprotein receptor activity.
UniProtKB/Swiss-Prot for CXCL16 Gene
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.