Aliases for CWC22 Gene
External Ids for CWC22 Gene
Previous GeneCards Identifiers for CWC22 Gene
GeneCards Summary for CWC22 Gene
CWC22 (CWC22 Spliceosome Associated Protein Homolog) is a Protein Coding gene. Diseases associated with CWC22 include Meningeal Melanomatosis and Melanomatosis. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression. Gene Ontology (GO) annotations related to this gene include RNA binding and binding.
UniProtKB/Swiss-Prot for CWC22 Gene
Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay.