Aliases for CTSW Gene
External Ids for CTSW Gene
Previous GeneCards Identifiers for CTSW Gene
The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq, Jul 2008]
GeneCards Summary for CTSW Gene
CTSW (Cathepsin W) is a Protein Coding gene. Diseases associated with CTSW include Autoimmune Atrophic Gastritis. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Lysosome. Gene Ontology (GO) annotations related to this gene include cysteine-type peptidase activity. An important paralog of this gene is CTSF.
UniProtKB/Swiss-Prot for CTSW Gene
May have a specific function in the mechanism or regulation of T-cell cytolytic activity.