Aliases for CTSV Gene
External Ids for CTSV Gene
Previous HGNC Symbols for CTSV Gene
Previous GeneCards Identifiers for CTSV Gene
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]
GeneCards Summary for CTSV Gene
CTSV (Cathepsin V) is a Protein Coding gene. Diseases associated with CTSV include Acquired Hyperkeratosis and Placenta Accreta. Among its related pathways are Degradation of the extracellular matrix and Innate Immune System. Gene Ontology (GO) annotations related to this gene include cysteine-type endopeptidase activity. An important paralog of this gene is CTSL.
UniProtKB/Swiss-Prot Summary for CTSV Gene
Cysteine protease. May have an important role in corneal physiology.