External Ids for CTSO Gene
Previous HGNC Symbols for CTSO Gene
Previous GeneCards Identifiers for CTSO Gene
The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase. [provided by RefSeq, Jul 2008]
GeneCards Summary for CTSO Gene
CTSO (Cathepsin O) is a Protein Coding gene. Diseases associated with CTSO include Orofaciodigital Syndrome V. Among its related pathways are Apoptosis Modulation and Signaling and Lysosome. Gene Ontology (GO) annotations related to this gene include cysteine-type endopeptidase activity and cysteine-type peptidase activity. An important paralog of this gene is CTSV.
UniProtKB/Swiss-Prot Summary for CTSO Gene
Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover.